Search Results - "Nakasone, Junko"

Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice by Kina-Tanada, Mika, Sakanashi, Mayuko, Tanimoto, Akihide, Kaname, Tadashi, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Uchida, Taro, Nakasone, Junko, Kozuka, Chisayo, Ishida, Masayoshi, Kubota, Haruaki, Taira, Yuji, Totsuka, Yuichi, Kina, Shin-ichiro, Sunakawa, Hajime, Omura, Junichi, Satoh, Kimio, Shimokawa, Hiroaki, Yanagihara, Nobuyuki, Maeda, Shiro, Ohya, Yusuke, Matsushita, Masayuki, Masuzaki, Hiroaki, Arasaki, Akira, Tsutsui, Masato

“…Aims/hypothesis Nitric oxide (NO) is synthesised not only from l -arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate…”
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Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects by Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Sakanashi, Mayuko, Hamadate, Naobumi, Uchida, Taro, Kina-Tanada, Mika, Kubota, Haruaki, Nakasone, Junko, Sakanashi, Matao, Ueda, Shinichiro, Masuzaki, Hiroaki, Ishiuchi, Shogo, Ohya, Yusuke, Tsutsui, Masato

“…Recent epidemiological studies have demonstrated that coffee drinking is associated with reduced mortality of cardiovascular disease. However, its precise…”
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Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo by Noguchi, Katsuhiko, Hamadate, Naobumi, Matsuzaki, Toshihiro, Sakanashi, Mayuko, Nakasone, Junko, Uchida, Taro, Arakaki, Kumiko, Kubota, Haruaki, Ishiuchi, Shogo, Masuzaki, Hiroaki, Sugahara, Kazuhiro, Ohya, Yusuke, Sakanashi, Matao, Tsutsui, Masato

“…An elevation of oxidized forms of tetrahydrobiopterin (BH(4)), especially dihydrobiopterin (BH(2)), has been reported in the setting of oxidative stress, such…”
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Long-Term Treatment With San’o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism by Sakanashi, Mayuko, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Nakasone, Junko, Sakanashi, Makiko, Uchida, Taro, Kina-Tanada, Mika, Kubota, Haruaki, Arakaki, Kumiko, Tanimoto, Akihide, Yanagihara, Nobuyuki, Sakanashi, Matao, Ohya, Yusuke, Masuzaki, Hiroaki, Ishiuchi, Shogo, Sugahara, Kazuhiro, Tsutsui, Masato

“…Background: Hormone replacement therapy has failed to reduce ischemic cardiovascular events in climacteric women. To explore alternative therapy, we examined…”
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Improvement of impaired endothelial function by tetrahydrobiopterin in stroke-prone spontaneously hypertensive rats by Noguchi, Katsuhiko, Hamadate, Naobumi, Matsuzaki, Toshihiro, Sakanashi, Mayuko, Nakasone, Junko, Sakanashi, Makiko, Tsutsui, Masato, Sakanashi, Matao

“…To investigate the role of tetrahydrobiopterin (BH4), an essential cofactor of nitric oxide synthase, in endothelial function in a model of genetic…”
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Effect of Decreased Levels of Intrinsic Tetrahydrobiopterin on Endothelial Function in Anesthetized Rats by Hamadate, Naobumi, Noguchi, Katsuhiko, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Nakasone, Junko, Sakanashi, Matao

“…Tetrahydrobiopterin (BH4) deficiency has been suggested to be an important factor in vascular endothelial dysfunction. In this study, we investigated the…”
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Beneficial effect of tetrahydrobiopterin on ischemia-reperfusion injury in isolated perfused rat hearts by Yamashiro, Satoshi, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Miyagi, Kanako, Nakasone, Junko, Sakanashi, Mayuko, Koja, Kageharu, Sakanashi, Matao

“…Objective: It has recently been proposed that nitric oxide synthase, in the presence of suboptimal levels of tetrahydrobiopterin, an essential cofactor of this…”
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Cardioprotective effects of extracts from Psidium guajava L and Limonium wrightii, Okinawan medicinal plants, against ischemia-reperfusion injury in perfused rat hearts by Yamashiro, Satoshi, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Miyagi, Kanako, Nakasone, Junko, Sakanashi, Mayuko, Sakanashi, Makoko, Kukita, Ichiro, Aniya, Yoko, Sakanashi, Matao

“…The aim of this study was to determine whether the medicinal herbs growing in Okinawa and possessing a radical-scavenging activity would exert cardioprotective…”
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Abstract 12185: Complete Disruption of All Nitric Oxide Synthases Markedly Reduces Cerebral Infarct Size After Middle Cerebral Artery Occlusion in Mice by Tsutsui, Masato, Haruaki, Kubota, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Hattori, Fumiya, Sakanashi, Mayuko, Kina-Tanada, Mika, Ishida, Masayoshi, Nakasone, Junko, Shimokawa, Hiroaki, Ohya, Yusuke, Sugahara, Kazuhiro, Kakinohana, Manabu

“…BackgroundThe role of each nitric oxide synthase (NOS) isoform in cerebral infarction has been studied in individual NOS isoform-deficient mice. It has been…”
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Abstract 13493: Complete Disruption of All Nitric Oxide Synthase Genes Markedly Reduces Cerebral Infarct Size after Middle Cerebral Artery Occlusion in Mice by Tsutsui, Masato, Kubota, Haruaki, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Hattori, Fumiya, Sakanashi, Mayuko, Kina-Tanada, Mika, Uchida, Taro, Nakasone, Junko, Shimokawa, Hiroaki, Ohya, Yusuke, Sugahara, Kazuhiro, Kakinohana, Manabu

“…Abstract only Background: The role of each nitric oxide synthase (NOS) isoform in the pathogenesis of cerebral infarction has been studied in individual NOS…”
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Abstract 12584: Combined Treatment With Irbesartan and Amlodipine Potently Prevents Acute Myocardial Infarction in Subtotally Nephrectomized Triple Nitric Oxide Synthases-Deficient Mice by Tsutsui, Masato, Uchida, Taro, Furuno, Yumi, Tanimoto, Akihide, Kina-Tanada, Mika, Kubota, Haruaki, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Nakasone, Junko, Ohya, Yusuke, Yanagihara, Nobuyuki, Shimokawa, Hiroaki, Tamura, Masahito, Otsuji, Yutaka

“…BackgroundSince there are few experimentally useful models that develop acute myocardial infarction (AMI), research and development of therapeutic strategies…”
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Development of an experimentally useful model of acute myocardial infarction: 2/3 nephrectomized triple nitric oxide synthases-deficient mouse by Uchida, Taro, Furuno, Yumi, Tanimoto, Akihide, Toyohira, Yumiko, Arakaki, Kumiko, Kina-Tanada, Mika, Kubota, Haruaki, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Nakasone, Junko, Igarashi, Tomonori, Ueno, Susumu, Matsushita, Masayuki, Ishiuchi, Shogo, Masuzaki, Hiroaki, Ohya, Yusuke, Yanagihara, Nobuyuki, Shimokawa, Hiroaki, Otsuji, Yutaka, Tamura, Masahito, Tsutsui, Masato

“…Abstract We investigated the effect of subtotal nephrectomy on the incidence of acute myocardial infarction (AMI) in mice deficient in all three nitric oxide…”
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Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats by Noguchi, Katsuhiko, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Nakasone, Junko, Sakanashi, Makiko, Koyama, Tomoyuki, Hamadate, Naobumi, Sakanashi, Matao

“…Haemodynamic effects of saline-extracted venom from nematocysts isolated from Chiropsalmus quadrigatus (Habu-kurage) were studied in anaesthetized rats…”
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Abstract 18357: Hypertension in Mice Lacking 3-Mercaptopyruvate Sulfurtransferase by Tsutsui, Masato, Totsuka, Yuichi, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Nakasone, Junko, Kuniyoshi, Yukio

“…BackgroundHydrogen sulfide (H2S) is synthesized by three distinct H2S synthase isoforms, including cystathionine gamma-lyase (CSE), cystathionine beta-synthase…”
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Abstract 17585: Long-term Dietary Nitrite and Nitrate Deficiency Causes Metabolic Syndrome in Mice by Tsutsui, Masato, Kina-Tanada, Mika, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Ishida, Masayoshi, Nakasone, Junko, Shimokawa, Hiroaki, Ohya, Yusuke, Arasaki, Akira

“…BackgroundNitric oxide (NO) is formed not only from L-arginine by a family of NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate…”
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Effect of blood hemoglobin concentration on depressor response to ACh in anesthetized dogs by Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Koyama, Tomoyuki, Nakasone, Junko, Sakanashi, Matao

“…Although in vitro inactivation of nitric oxide by hemoglobin (Hgb) has been well described, the possibility that blood Hgb concentration could regulate nitric…”
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Responsiveness of aorta isolated from non-diabetic and diabetic rats in different concentrations of extracellular calcium by Nakasone, Junko, Higuchi, Makie, Miyagi, Kanako, Sakanashi, Matao

“…Contractile responses of aortas isolated from non-diabetic and 6-week streptozotocin-induced diabetic rats to α-adrenoceptor agonists and KCl were examined in…”
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Haemodynamic effects of the crude venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rabbits by Koyama, Tomoyuki, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Sakanashi, Mayuko, Nakasone, Junko, Miyagi, Kanako, Sakanashi, Makiko, Sakanashi, Matao

“…Haemodynamic effects of saline-extracted venom from nematocysts isolated from tentacles of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) were…”
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PROSTACYCLIN CAUSES SPLENIC DILATION AND HAEMATOLOGICAL CHANGE IN DOGS by Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Ojiri, Yoshihiko, Sakanashi, Mayuko, Nakasone, Junko, Sakanashi, Matao

“…SUMMARY 1 The effect of vasodilators on spleen volume and the blood storage function is not yet well elucidated. To this end, in the present study the effects…”
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Responsiveness of diabetic rat aorta to KCl, and alpha-adrenergic agents by Nakasone, Junko, Higuchi, Makie, Iha, Rieko, Sakanashi, Matao

“…The sensitivity and efficacy of 6-week streptozotocin-induced diabetic rat aorta to KCl, norepinephrine and clonidine were examined. The developed isometric…”
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