Search Results - "Nakashiro, Koh‐ichi"

MicroRNA‐361‐3p is a potent therapeutic target for oral squamous cell carcinoma by Ogawa, Himiko, Nakashiro, Koh‐ichi, Tokuzen, Norihiko, Kuribayashi, Nobuyuki, Goda, Hiroyuki, Uchida, Daisuke

“…MicroRNAs (miRNAs) can act not only as tumor suppressor genes but also as oncogenes. Oncogenic miRNAs (oncomiRs) could therefore provide opportunities for the…”
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Possible Role of miR-375-3p in Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma by Saika, Masato, Nakashiro, Koh-Ichi, Tokuzen, Norihiko, Shirai, Hiroyuki, Uchida, Daisuke

“…No clinically useful predictors of latent cervical lymph node metastasis (LNM) in early oral squamous cell carcinoma (OSCC) are available. In this study, we…”
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Determination of the origin of oral squamous cell carcinoma by microarray analysis: Squamous epithelium or minor salivary gland? by Kinouchi, Makoto, Izumi, Sayaka, Nakashiro, Koh‐ichi, Haruyama, Yasuo, Kobashi, Gen, Uchida, Daisuke, Hasegawa, Tomonori, Kawamata, Hitoshi

“…More than 90% of oral cancers are histopathologically squamous cell carcinomas (SCCs). According to clinical behavior and histopathological features, we…”
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KRT13 and UPK1B for differential diagnosis between metastatic lung carcinoma from oral squamous cell carcinoma and lung squamous cell carcinoma by Goda, Hiroyuki, Nakashiro, Koh-ichi, Sano, Yoshifumi, Adachi, Tomoko, Tokuzen, Norihiko, Kuribayashi, Nobuyuki, Hino, Satoshi, Uchida, Daisuke

“…Oral squamous cell carcinomas unusually show distant metastasis to the lung after primary treatment, which can be difficult to differentiate from primary…”
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MicroRNA-1289 Functions as a Novel Tumor Suppressor in Oral Squamous Cell Carcinoma by Nakashiro, Koh-ichi, Tokuzen, Norihiko, Saika, Masato, Shirai, Hiroyuki, Kuribayashi, Nobuyuki, Goda, Hiroyuki, Uchida, Daisuke

“…Recently, numerous tumor-suppressive microRNAs (TS-miRs) have been identified in human malignancies. Here, we attempted to identify novel TS-miRs in oral…”
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Serum CXCL13 as a Novel Biomarker in Oral Squamous Cell Carcinoma by Tojo, Shin, Nakashiro, Koh‐ichi, Kuribayashi, Nobuyuki, Uchida, Daisuke

“…Background Despite its low sensitivity (approximately 30%), squamous cell carcinoma (SCC) antigen is commonly utilized as a serum tumor marker for oral SCC…”
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Inverse correlation between the number of CXCR3+ macrophages and the severity of inflammatory lesions in Sjögren's syndrome salivary glands: A pilot study by Aota, Keiko, Yamanoi, Tomoko, Kani, Koichi, Nakashiro, Koh‐ichi, Ishimaru, Naozumi, Azuma, Masayuki

“…Background Mechanisms underlying immune cells’ recruitment and activation into the inflammatory lesions of lip salivary glands (LSGs) from primary Sjögren's…”
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Prognostic significance of interleukin-8 and CD163-positive cell-infiltration in tumor tissues in patients with oral squamous cell carcinoma by Fujita, Yohei, Okamoto, Masato, Goda, Hiroyuki, Tano, Tomoyuki, Nakashiro, Koh-ichi, Sugita, Atsuro, Fujita, Tomonobu, Koido, Shigeo, Homma, Sadamu, Kawakami, Yutaka, Hamakawa, Hiroyuki

“…We investigated whether serum interleukin (IL)-8 reflects the tumor microenvironment and has prognostic value in patients with oral squamous cell carcinoma…”
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Human papillomavirus‑16 infection and p16 expression in oral squamous cell carcinoma by Tokuzen, Norihiko, Nakashiro, Koh-Ichi, Tojo, Shin, Goda, Hiroyuki, Kuribayashi, Nobuyuki, Uchida, Daisuke

“…Human papillomavirus (HPV) is a possible carcinogenetic factor in oral squamous cell carcinoma (OSCC). Previous studies have reported the prevalence of HPV in…”
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Therapeutic potential of targeting cell division cycle associated 5 for oral squamous cell carcinoma by Tokuzen, Norihiko, Nakashiro, Koh-ichi, Tanaka, Hiroshi, Iwamoto, Kazuki, Hamakawa, Hiroyuki

“…Molecularly targeted drugs are used in the treatment of a variety of malignant tumors, but this approach to developing novel therapies for oral squamous cell…”
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Paclitaxel Potentiates the Anticancer Effect of Cetuximab by Enhancing Antibody-Dependent Cellular Cytotoxicity on Oral Squamous Cell Carcinoma Cells In Vitro by Sawatani, Yuta, Komiyama, Yuske, Nakashiro, Koh-Ichi, Uchida, Daisuke, Fukumoto, Chonji, Shimura, Michiko, Hasegawa, Tomonori, Kamimura, Ryouta, Hitomi-Koide, Masayo, Hyodo, Toshiki, Kawamata, Hitoshi

“…Administration of cetuximab (C-mab) in combination with paclitaxel (PTX) has been used for patients with head and neck squamous cell carcinoma (SCC)…”
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Conditional deletion of Stat3 promotes neurogenesis and inhibits astrogliogenesis in neural stem cells by Cao, Fang, Hata, Ryuji, Zhu, Pengxiang, Nakashiro, Koh-ichi, Sakanaka, Masahiro

“…Although signal transducer and activator of transcription 3 (Stat3) plays crucial roles in the determination of neural stem cell (NSC) fate, Stat3 has multiple…”
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The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells by Sakaue, Tomohisa, Sakakibara, Iori, Uesugi, Takahiro, Fujisaki, Ayako, Nakashiro, Koh-ichi, Hamakawa, Hiroyuki, Kubota, Eiji, Joh, Takashi, Imai, Yuuki, Izutani, Hironori, Higashiyama, Shigeki

“…Vascular endothelial cell growth factor receptor 2 (VEGFR2) is an essential receptor for the homeostasis of endothelial cells. In this study, we showed that…”
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Whole Exome Sequencing of SMO , BRAF , PTCH1 and GNAS in Odontogenic Diseases by Shimura, Michiko, Nakashiro, Koh-Ichi, Sawatani, Yuta, Hasegawa, Tomonori, Kamimura, Ryota, Izumi, Sayaka, Komiyama, Yuske, Fukumoto, Chonji, Yagisawa, Shuma, Yaguchi, Erika, Hitomi-Koide, Masayo, Hyodo, Toshiki, Uchida, Daisuke, Kawamata, Hitoshi

“…Odontogenic diseases are diagnosed based on clinical course, imaging, and histopathology. However, a definitive diagnosis is not always possible. We analyzed…”
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Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system by Fukuda, Shinji, Nishida-Fukuda, Hisayo, Nanba, Daisuke, Nakashiro, Koh-ichi, Nakayama, Hironao, Kubota, Hiroyuki, Higashiyama, Shigeki

“…Epithelial cell plasticity is controlled by extracellular cues, but the underlying mechanisms remain to be fully understood. Epidermal growth factor (EGF) and…”
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Prognostic impact of preoperative serum interleukin-6 levels in patients with early-stage oral squamous cell carcinoma, defined by sentinel node biopsy by Goda, Hiroyuki, Okamoto, Masato, Nakashiro, Koh-Ichi, Hino, Satoshi, Murase, Ryuichi, Hamakawa, Hiroyuki

“…Failure to detect recurrence and lymph node metastasis early represents a fundamental barrier to the improvement of survival rate in early stage oral squamous…”
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Ribonucleotide reductase M2 is a promising molecular target for the treatment of oral squamous cell carcinoma by IWAMOTO, KAZUKI, NAKASHIRO, KOH-ICHI, TANAKA, HIROSHI, TOKUZEN, NORIHIKO, HAMAKAWA, HIROYUKI

“…In our previous study, ribonucleotide reductase M2 (RRM2) was identified as a cancer-related gene commonly overexpressed in human oral squamous cell carcinoma…”
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Distinct Regulation of CXCL10 Production by Cytokines in Human Salivary Gland Ductal and Acinar Cells by Aota, Keiko, Kani, Koichi, Yamanoi, Tomoko, Nakashiro, Koh-ichi, Ishimaru, Naozumi, Azuma, Masayuki

“…CXCL10, a CXC chemokine induced by interferon-gamma [IFN-γ], has been observed in a wide variety of chronic inflammatory disorders and autoimmune conditions…”
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Up‐regulation of DNA‐dependent protein kinase correlates with radiation resistance in oral squamous cell carcinoma by Shintani, Satoru, Mihara, Mariko, Li, Chunnan, Nakahara, Yuuji, Hino, Satoshi, Nakashiro, Koh‐ichi, Hamakawa, Hiroyuki

“…DNA‐PK is a nuclear protein with serine/threonine kinase activity and forms a complex consisting of the DNA‐PKcs and a heterodimer of Ku70 and Ku80 proteins…”
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Pathophysiology of lung injury induced by common bile duct ligation in mice by Shikata, Fumiaki, Sakaue, Tomohisa, Nakashiro, Koh-ichi, Okazaki, Mikio, Kurata, Mie, Okamura, Toru, Okura, Masahiro, Ryugo, Masahiro, Nakamura, Yuki, Yasugi, Takumi, Higashiyama, Shigeki, Izutani, Hironori

“…Liver dysfunction and cirrhosis affect vasculature in several organ systems and cause impairment of organ functions, thereby increasing morbidity and…”
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