Search Results - "Nakao, Syuhei"

Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs by Nakao, Syuhei, Mabuchi, Miyuki, Shimizu, Tadashi, Itoh, Yoshihiro, Takeuchi, Yuko, Ueda, Masahiro, Mizuno, Hiroaki, Shigi, Naoko, Ohshio, Ikumi, Jinguji, Kentaro, Ueda, Yuko, Yamamoto, Masatatsu, Furukawa, Tatsuhiko, Aoki, Shunji, Tsujikawa, Kazutake, Tanaka, Akito

“…A series of 1-aryl-3,4-substituted-1H-pyrazol-5-ol derivatives was synthesized and evaluated as prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors to obtain a…”
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Newly synthesized anticancer drug HUHS1015 is effective on malignant pleural mesothelioma by Kaku, Yoshiko, Nagaya, Hisao, Tsuchiya, Ayako, Kanno, Takeshi, Gotoh, Akinobu, Tanaka, Akito, Shimizu, Tadashi, Nakao, Syuhei, Tabata, Chiharu, Nakano, Takashi, Nishizaki, Tomoyuki

“…The newly synthesized naftopidil analogue HUHS1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO‐211H, NCI‐H28, NCI‐H2052, and…”
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Effects of Newly Synthesized DCP-LA-Phospholipids on Protein Kinase C and Protein Phosphatases by Kanno, Takeshi, Tsuchiya, Ayako, Shimizu, Tadashi, Nakao, Syuhei, Tanaka, Akito, Nishizaki, Tomoyuki

“…Background/Aims: The linoleic acid derivative DCP-LA selectively activates PKCε and inhibits protein phosphatase 1 (PP1). In the present study, we have newly…”
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DCP-LA-Phosphatidylinositol and Its Enantiomer Exhibit Different Bioactivities by Tsuchiya, Ayako, Kanno, Takeshi, Shimizu, Tadashi, Nakao, Syuhei, Tanaka, Akito, Nishizaki, Tomoyuki

“…Background/Aims: The present study was conducted to understand biochemical and biological characteristics of the phosphatidylinositol (PI) derivative…”
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Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor by Nakao, Syuhei, Mabuchi, Miyuki, Wang, Shenglan, Kogure, Yoko, Shimizu, Tadashi, Noguchi, Koichi, Tanaka, Akito, Dai, Yi

“…[Display omitted] A series of 31 resveratrol derivatives was designed, synthesized and evaluated for activation and inhibition of the TRPA1 channel. Most acted…”
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Early postoperative physical therapy for improving short-term gross motor outcome in infants with cyanotic and acyanotic congenital heart disease by Haseba, Sumihito, Sakakima, Harutoshi, Nakao, Syuhei, Ohira, Misaki, Yanagi, Shigefumi, Imoto, Yutaka, Yoshida, Akira, Shimodozono, Megumi

“…Purpose: We analysed the gross motor recovery of infants and toddlers with cyanotic and acyanotic congenital heart disease (CHD) who received early…”
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Combined effects of repeated sauna therapy and exercise training on cardiac function and physical activity in patients with chronic heart failure by Haseba, Sumihito, Sakakima, Harutoshi, Kubozono, Takuro, Nakao, Syuhei, Ikeda, Satoshi

“…Purpose: We investigated the combined effects of repeated sauna therapy and exercise training on subjective symptoms, cardiac function, daily activities and…”
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Identification of HUHS190, a human naftopidil metabolite, as a novel anti-bladder cancer drug by Shimizu, Tadashi, Yamaguchi, Keiko, Yamamoto, Momoka, Kurioka, Rina, Kino, Yukari, Matsunaga, Wataru, Nakao, Syuhei, Fukuhara, Hiroshi, Tanaka, Akito, Gotoh, Akinobu, Mabuchi, Miyuki

“…[Display omitted] We carried out structure-activity relationship study on anti-cancer effects of naftopidil (1) and its metabolites, resulted in identification…”
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Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model by Mabuchi, Miyuki, Ueda, Masahiro, Yoshida, Yuri, Horiike, Kota, Yamaoka, Kenta, Nakao, Syuhei, Shimizu, Tadashi, Ueda, Yuko, Tsujikawa, Kazutake, Tanaka, Akito

“…The inhibitory activities of docetaxel at a wide range of doses (0.1-10 mg/kg; subcutaneously (s.c.), once/week) in nude mice bearing a human prostate cancer…”
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A novel PP2A enhancer induces caspase-independent apoptosis of MKN28 gastric cancer cells with high MEK activity by Tsuchiya, Ayako, Kanno, Takeshi, Shimizu, Tadashi, Nakao, Syuhei, Tanaka, Akito, Tabata, Chiharu, Nakano, Takashi, Nishizaki, Tomoyuki

“…Abstract The newly synthesized phosphatidylinositol (PI) derivative 1,2- O -bis-[8-{2-(2-pentyl-cyclopropylmethyl)-cyclopropyl}-octanoyl]- sn…”
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Improving the bioavailability and anticancer effect of the PCA-1/ALKBH3 inhibitor HUHS015 using sodium salt by Mabuchi, Miyuki, Shimizu, Tadashi, Ueda, Masahiro, Sasakawa, Yuka, Nakao, Syuhei, Ueda, Yuko, Kawamura, Akio, Tsujikawa, Kazutake, Tanaka, Akito

“…Prostate cancer antigen (PCA)-1/AlkB homologue 3 (ALKBH3) has been identified as a clinically significant factor and siRNA of PCA-1 inhibits DU145…”
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Newly synthesized anticancer drug HUHS 1015 is effective on malignant pleural mesothelioma by Kaku, Yoshiko, Nagaya, Hisao, Tsuchiya, Ayako, Kanno, Takeshi, Gotoh, Akinobu, Tanaka, Akito, Shimizu, Tadashi, Nakao, Syuhei, Tabata, Chiharu, Nakano, Takashi, Nishizaki, Tomoyuki

“…The newly synthesized naftopidil analogue HUHS 1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO ‐211H, NCI ‐H28, NCI ‐H2052, and…”
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Broadband circularly polarized cavity-backed antenna by Joseph, R, Nakao, S, Fukusako, T

“…The design and experimental investigation of a circularly polarized antenna with circular slot for broadband characteristics is proposed. The horizontal and…”
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