Search Results - "Nakao, Mika"
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A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes
Published in International journal of molecular sciences (31-10-2019)“…Insulin-stimulated glucose uptake is mediated by translocation of the glucose transporter GLUT4 to the plasma membrane in adipocytes and skeletal muscle cells…”
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2
The guanine nucleotide exchange factor FLJ00068 activates Rac1 in adipocyte insulin signaling
Published in FEBS letters (01-12-2020)“…Insulin stimulates glucose uptake via the translocation of the glucose transporter GLUT4 to the plasma membrane in adipocytes. Several lines of evidence…”
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Successful Control of Hypercalcemia with Sorafenib, Evocalcet, and Denosumab Combination Therapy for Recurrent Parathyroid Carcinoma
Published in Internal Medicine (15-11-2022)“…Parathyroid carcinoma (PC) is a rare type of endocrine cancer. Recurrence and metastasis are common after surgery, and refractory hypercalcemia often leads to…”
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4
A Low Crizotinib Concentration in the Cerebrospinal Fluid Causes Ineffective Treatment of Anaplastic Lymphoma Kinase-positive Non-small Cell Lung Cancer with Carcinomatous Meningitis
Published in Internal Medicine (01-03-2019)“…The central nervous system is a common site of relapse in patients receiving crizotinib, which is presumed to be associated with the low concentration of…”
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5
Lipoid Pneumonia Caused by Esophageal Achalasia
Published in Internal Medicine (01-02-2024)“…A 59-year-old man presented with esophageal achalasia complicated by lipoid pneumonia. Dysphagia and diffuse ground-glass shadows on computed tomography led to…”
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6
Disseminated Nocardiosis Initially Manifesting as Visual Field Defects
Published in Internal Medicine (15-02-2019)Get full text
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7
Comparative Analysis of the Attitudes toward Palliative Care between Medical Oncologists and Pulmonologists
Published in Internal Medicine (15-09-2021)“…Objective In Japan, both medical oncologists and pulmonologists treat lung cancer patients; however, the difference in their attitude toward palliative care…”
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Reproducible abscopal effect in a patient with lung cancer who underwent whole‐brain irradiation and atezolizumab administration
Published in Thoracic cancer (01-03-2021)“…Due to the emergence of immune checkpoint inhibitors, the abscopal effect has gained more attention. We report a case of extracranial abscopal effect after…”
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9
Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
Published in Internal Medicine (15-07-2019)“…A 43-year-old man with malignant lymphoma who had been treated with the cyclosphamide, vincrstine, procarbazine, and prednisolone (C-MOPP) regimen was admitted…”
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10
Ability of the Glasgow Prognostic Score to predict the tolerability and efficacy of platinum-combination chemotherapy among elderly patients with advanced non-small cell lung cancer
Published in The Journal of Medical Investigation (2021)“…Background : Although platinum-combination chemotherapy is widely used to treat advanced non-small cell lung cancer (NSCLC), not all elderly patients benefit…”
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11
Prognosis of frail older patients treated with intubation and artificial ventilation for respiratory failure
Published in The Journal of Medical Investigation (2023)“…Background:Older patients with severe respiratory failure have higher mortality rates and are more likely to experience impairments in activities of daily…”
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Translational and Randomized Study of 5-HT3 Receptor Antagonists for Evaluation of Chemotherapy-induced Nausea and Vomiting Related Biomarkers
Published in The Journal of Medical Investigation (2019)“…Purpose We assessed the efficacy of palonosetron (PAL) in comparison to granisetron (GRA) for the treatment of CINV using the self-assessment questionnaires…”
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13
An 83‐year‐old patient with RET fusion‐positive non‐small cell lung cancer experiencing severe hepatic disorder due to selpercatinib administration
Published in Respirology case reports (01-05-2023)“…An 83‐year‐old woman with RET fusion‐positive advanced lung adenocarcinoma was administered selpercatinib 320 mg/day. Despite the shrinking of the tumour,…”
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14
Comparative postoperative outcomes of GGN-dominant vs single lesion lung adenocarcinomas
Published in Journal of cardiothoracic surgery (22-06-2020)“…Abstract Background Multiple synchronous ground glass nodules (GGNs) are known to be malignant, however, they tend to progress slowly. Multiple synchronous…”
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15
Prospective clinical trial evaluating vulnerability and chemotherapy risk using geriatric assessment tools in older patients with lung cancer
Published in Geriatrics & gerontology international (01-11-2019)“…Aim In Japan, the number of older patients with cancer has been increasing. Assessment of performance status, cognitive function and social background is…”
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An endobronchial hamartoma observed using narrow band imaging under saline injection: A case report
Published in Respirology case reports (01-07-2022)“…A light blue line (LBL) was observed along the edge of a lesion using narrow band imaging under saline injection during bronchoscopy in an 82‐year‐old patient…”
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17
Comparison of Ultra-Magnifying Endocytoscopic and Hematoxylin-Eosin-Stained Images of Lung Specimens
Published in Diagnostics (Basel) (01-03-2023)“…Endocytoscopy enables real-time observation of lesions at ultra-magnification. In the gastrointestinal and respiratory fields, endocytoscopic images are…”
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A phase II study of atezolizumab with bevacizumab, carboplatin, and paclitaxel for patients with EGFR-mutated NSCLC after TKI treatment failure (NEJ043 study)
Published in European journal of cancer (1990) (01-01-2024)“…Treatment options for patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) after EGFR-tyrosine kinase inhibitor…”
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ERCC1 Is a Predictive Biomarker for Non-small Cell Lung Cancer But Is Antibody-dependent
Published in Anticancer research (01-05-2021)“…To predict the efficacy of platinum-containing chemotherapy, ERCC1 expression levels were investigated. Studies have shown changes in the performance of…”
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MO1-2 Subgroup analysis of atezo + bev + carbo + pac for previously treated patients with EGFRm NSCLC (NEJ043)
Published in Annals of oncology (01-11-2023)Get full text
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