Search Results - "Nakamura, Takaaki"

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase by FURUTA, Yousuke, KOMENO, Takashi, NAKAMURA, Takaaki

“…Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is an anti-viral agent that selectively and potently inhibits the RNA-dependent RNA polymerase…”
Get full text

A case of central diabetes insipidus due to neurophysin II gene abnormality diagnosed based on a family history of nocturnal enuresis by Sugawara, Lucia, Nakamura, Takaaki, Ishizuka, Yoshitaka, Maegawa, Hiroshi

“…The etiology of central diabetes insipidus (DI) is classified into (1) idiopathic, (2) familial, and (3) secondary. Of these, familial central diabetes…”
Get full text

Spectral Properties of Nonlinear Schrödinger Equation on a Ring by Nakamura, Takaaki, Cheon, Taksu

“…The stationary states of nonlinear Schrodinger equation on a ring with a defect is numerically analyzed. Unconventional connection conditions are imposed on…”
Get full text

Potentiated antitumor effects of APS001F/5-FC combined with anti-PD-1 antibody in a CT26 syngeneic mouse model by Shioya, Koichiro, Matsumura, Tomio, Seki, Yuji, Shimizu, Hitomi, Nakamura, Takaaki, Taniguchi, Shun'ichiro

“…APS001F is a strain of Bifidobacterium longum genetically engineered to express cytosine deaminase that converts 5-fluorocytosine (5-FC) to 5-fluorouracil. In…”
Get full text

Peculiar Unpleasant Dysgeusia as the Sole Initial Symptom of Guillain-Barré Syndrome by Nakamura, Takaaki, Tsukita, Kenichi, Suzuki, Asako, Watanabe, Genya, Harada, Ryuhei, Kawasaki, Emiko, Chiba, Tetsuya, Sugaya, Ryo, Suzuki, Yasushi

“…Dysgeusia is rare in Guillain-Barré syndrome, particularly as the initial symptom. We herein report the case of a 59-year-old woman who presented with only…”
Get full text

Early neurosyphilis presenting with multiple cranial nerve palsies: A case report of management by combined penicillin-corticosteroid treatment by Komamura, Hiroshi, Nakamura, Takaaki, Kobayashi, Junpei, Harada, Ryuhei, Endo, Kaoru, Ogura, Masaki, Higuchi, Jun

“…Early neurosyphilis commonly appears in basilar meninges, and its meningeal inflammation can spread to neighboring cranial nerves, resulting in some cranial…”
Get full text

T-cell Lymphoma Presenting Neutrophilic Inflammation in the Cerebrospinal Fluid by Nakamura, Takaaki, Takai, Yoshiki, Kaneko, Kimihiko, Kuroda, Hiroshi, Misu, Tatsuro, Asanuma, Kiyotaka, Saito, Ryoko, Aoki, Masashi

“…A 66-year-old woman presented with upper abdominal pain and weakness in the limbs. She had bilateral uveitis and gastric ulcers. A neurological examination…”
Get full text

Dysregulation of SNX1-retromer axis in pharmacogenetic models of Parkinson’s disease by Yoshida, Shun, Hasegawa, Takafumi, Nakamura, Takaaki, Sato, Kazuki, Sugeno, Naoto, Ishiyama, Shun, Sekiguchi, Kiyotoshi, Tobita, Muneshige, Takeda, Atsushi, Aoki, Masashi

“…Since the identification of vacuolar protein sorting (VPS) 35, as a causative molecule for familial Parkinson’s disease (PD), retromer-mediated endosomal…”
Get full text

Possible modulation of the amplitude and frequency of resting parkinsonian tremor by touching the trapezius muscle by Hasegawa, Takafumi, Ishiyama, Shun, Nakamura, Takaaki

“…The pathophysiological mechanism of resting tremor in Parkinson's disease remains obscure. Spinal/peripheral mechanisms may modulate oscillatory activity from…”
Get full text

Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial by Uzu, Takashi, Araki, Shin-Ichi, Kashiwagi, Atsunori, Haneda, Masakazu, Koya, Daisuke, Yokoyama, Hiroki, Kida, Yasuo, Ikebuchi, Motoyoshi, Nakamura, Takaaki, Nishimura, Masataka, Takahara, Noriko, Obata, Toshiyuki, Omichi, Nobuyuki, Sakamoto, Katsuhiko, Shingu, Ryosuke, Taki, Hideki, Nagai, Yoshio, Tokuda, Hiroaki, Kitada, Munehiro, Misawa, Miwa, Nishiyama, Akira, Kobori, Hiroyuki, Maegawa, Hiroshi

“…In patients with diabetes, albuminuria is a risk marker of end-stage renal disease and cardiovascular events. An increased renin-angiotensin system activity…”
Get full text

18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies by Ezura, Michinori, Kikuchi, Akio, Okamura, Nobuyuki, Ishiki, Aiko, Hasegawa, Takafumi, Harada, Ryuichi, Watanuki, Shoichi, Funaki, Yoshihito, Hiraoka, Kotaro, Baba, Toru, Sugeno, Naoto, Yoshida, Shun, Kobayashi, Junpei, Kobayashi, Michiko, Tano, Ohito, Ishiyama, Shun, Nakamura, Takaaki, Nakashima, Ichiro, Mugikura, Shunji, Iwata, Ren, Taki, Yasuyuki, Furukawa, Katsutoshi, Arai, Hiroyuki, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Takeda, Atsushi, Aoki, Masashi

“…Introduction: We aimed to determine whether in vivo tau deposits and monoamine oxidase B (MAO-B) detection using 18 F-THK5351 positron emission tomography…”
Get full text

Atypical macroglossia caused by multiple myeloma‐associated systemic amyloidosis with severe lingual movement disorder and tongue sclerosis by Murakami, Yumi, Watanabe, Genya, Yuki, Tsubasa, Sugaya, Ryo, Harigae, Souske, Nakamura, Takaaki, Kawasaki, Emiko, Tsukita, Kenichi, Watanabe, Mai, Harashima, Shogo, Suzuki, Hiroyoshi, Suzuki, Yasushi

“…A 70‐year‐old man presented with dysphagia and difficulty in moving the tongue. Macroscopic findings showed features resembling mild tongue atrophy. We…”
Get full text

A rare case of extramedullary-intradural hemangioblastoma in the thoracic spine by Taniguchi, Shoichi, Ogikubo, Osamu, Nakamura, Takaaki, Yamagishi, Itsuro, Hayakawa, Kazuo, Otsuka, Takanobu, Katoh, Tetsuji

“…STUDY DESIGN.: Case report. OBJECTIVE.: To present a rare case of extramedullary-intradural hemangioblastoma in the thoracic spine and to review the literature…”
Get full text

Lack of cross‐resistance to FF‐10501, an inhibitor of inosine‐5′‐monophosphate dehydrogenase, in azacitidine‐resistant cell lines selected from SKM‐1 and MOLM‐13 leukemia cell lines by Murase, Motohiko, Iwamura, Hiroyuki, Komatsu, Kensuke, Saito, Motoki, Maekawa, Toshihiko, Nakamura, Takaaki, Yokokawa, Takuya, Shimada, Yasuhiro

“…Resistance to azacitidine is a major issue in the treatments of myelodysplastic syndrome and acute myeloid leukemia, and previous studies suggest that changes…”
Get full text

Combined Expression of Pancreatic Duodenal Homeobox 1 and Islet Factor 1 Induces Immature Enterocytes to Produce Insulin by KOJIMA, Hideto, NAKAMURA, Takaaki, YASUDA, Hitoshi, KOJIMA, Itaru, SENO, Masaharu, WONG, Norman C. W, KIKKAWA, Ryuichi, KASHIWAGI, Atsunori, FUJITA, Yukihiro, KISHI, Akio, FUJIMIYA, Mineko, YAMADA, Syu, KUDO, Motoi, NISHIO, Yoshihiko, MAEGAWA, Hiroshi, HANEDA, Masakazu

“…Combined Expression of Pancreatic Duodenal Homeobox 1 and Islet Factor 1 Induces Immature Enterocytes to Produce Insulin Hideto Kojima 1 , Takaaki Nakamura 2 ,…”
Get full text

Insulin Activates CCAAT/Enhancer Binding Proteins and Proinflammatory Gene Expression through the Phosphatidylinositol 3-Kinase Pathway in Vascular Smooth Muscle Cells by Sekine, Osamu, Nishio, Yoshihiko, Egawa, Katsuya, Nakamura, Takaaki, Maegawa, Hiroshi, Kashiwagi, Atsunori

“…Phosphatidylinositol 3-kinase (PI3K) is a key molecule mediating signals of insulin in vascular smooth muscle cells (VSMCs). To examine the effect of chronic…”
Get full text

Protein-tyrosine Phosphatase 1B as New Activator for Hepatic Lipogenesis via Sterol Regulatory Element-binding Protein-1 Gene Expression by Shimizu, Shinya, Ugi, Satoshi, Maegawa, Hiroshi, Egawa, Katsuya, Nishio, Yoshihiko, Yoshizaki, Takeshi, Shi, Kun, Nagai, Yoshio, Morino, Katsutaro, Nemoto, Ken-ichi, Nakamura, Takaaki, Bryer-Ash, Michael, Kashiwagi, Atsunori

“…Like hyperglycemia, postprandial (diet-induced) hypertriglyceridemia is thought to play crucial roles in the pathogenesis of insulin resistant/metabolic…”
Get full text

Effects of Glucose and Insulin on Rat Apolipoprotein A-I Gene Expression by Murao, K, Wada, Y, Nakamura, T, Taylor, A H, Mooradian, A D, Wong, N C

“…We have examined the regulation of apolipoprotein A-I (apoA-I) gene expression in response to glucose and insulin. In Hep G2 cells, endogenous apoA-I mRNA was…”
Get full text

Regulation of ATP-sensitive Potassium Channel Subunit Kir6.2 Expression in Rat Intestinal Insulin-producing Progenitor Cells by Hashimoto, Tetsuya, Nakamura, Takaaki, Maegawa, Hiroshi, Nishio, Yoshihiko, Egawa, Katsuya, Kashiwagi, Atsunori

“…We have reported that the combined expression of Pdx-1 (pancreatic duodenal homeobox 1) and Isl-1 (islet 1) enables immature rat enterocytes (IEC-6) to produce…”
Get full text

Protein-Tyrosine Phosphatase 1B Associates with Insulin Receptor and Negatively Regulates Insulin Signaling without Receptor Internalization by Shi, Kun, Egawa, Katsuya, Maegawa, Hiroshi, Nakamura, Takaaki, Ugi, Satoshi, Nishio, Yoshihiko, Kashiwagi, Atsunori

“…Phosphorylated platelet-derived growth factor (PDGF) receptor becomes internalized and then is dephosphorylated by protein-tyrosine phosphatase (PTP) 1B at the…”
Get full text