Search Results - "Nakamura, Tânia Ueda"
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Terpenes from Copaifera Demonstrated in Vitro Antiparasitic and Synergic Activity
Published in Journal of medicinal chemistry (12-04-2012)“…To discover new possible therapies for Chagas' disease, we evaluated against all Trypanosoma cruzi life stages the in vitro trypanocidal and synergistic…”
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Antiproliferative Activity and Ultrastructural Changes in Promastigote and Amastigote forms of Leishmania amazonensis Caused by Limonene‐Acylthiosemicarbazide Hybrids
Published in Chemistry & biodiversity (01-07-2023)“…Leishmaniasis is a tropical zoonotic disease. It is found in 98 countries, with an estimated 1.3 million people being affected annually. During the life cycle,…”
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Hybrid materials for bone tissue engineering from biomimetic growth of hydroxiapatite on cellulose nanowhiskers
Published in Carbohydrate polymers (05-11-2016)“…•Cellulose nanowhiskers (CNWs) are used to drive hydroxyapatite (HAp) growth.•Negatively charged surface groups, sulfate and phosphate, have positive effect on…”
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Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Chronic UVB exposure promotes oxidative stress, directly causes molecular damage, and induces aging-related signal transduction, leading to skin photoaging…”
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5
Multifunctional Nanoparticles as High-Efficient Targeted Hypericin System for Theranostic Melanoma
Published in Polymers (30-12-2022)“…Biotin, spermine, and folic acid were covalently linked to the F127 copolymer to obtain a new drug delivery system designed for HY-loaded PDT treatment against…”
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Activity and Cell-Death Pathway in Leishmania infantum Induced by Sugiol: Vectorization Using Yeast Cell Wall Particles Obtained From Saccharomyces cerevisiae
Published in Frontiers in cellular and infection microbiology (14-06-2019)“…Visceral leishmaniasis, caused by , is a neglected tropical disease, to which efforts in the innovation of effective and affordable treatments remain limited,…”
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Proanthocyanidin Polymer-Rich Fraction of Stryphnodendron adstringens Promotes in Vitro and in Vivo Cancer Cell Death via Oxidative Stress
Published in Frontiers in pharmacology (03-07-2018)“…Cervical cancer is the fourth most common cancer that affects women, mainly through human papilloma virus (HPV) infection with high-risk HPV16 and HPV18. The…”
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Effect of elatol, isolated from red seaweed Laurencia dendroidea, on Leishmania amazonensis
Published in Marine drugs (29-10-2010)“…In the present study, we investigated the antileishmanial activity of sesquiterpene elatol, the major constituent of the Brazilian red seaweed Laurencia…”
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In Vitro and In Vivo Trypanocidal Synergistic Activity of N-Butyl-1-(4-Dimethylamino)Phenyl-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxamide Associated with Benznidazole
Published in Antimicrobial Agents and Chemotherapy (2012)“…American trypanosomiasis, or Chagas' disease, is caused by Trypanosoma cruzi and affects around 15 million people throughout the American continent. The…”
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Evaluation of the antiproliferative activity of the leaves from Arctium lappa by a bioassay-guided fractionation
Published in Molecules (Basel, Switzerland) (14-02-2012)“…Arctium lappa L. (Asteraceae) is used in folk medicine around the World, and shows several kinds of biological activity, particularly in vitro antitumor…”
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Tanacetum vulgare: antiherpes virus activity of crude extract and the purified compound parthenolide
Published in Phytotherapy research (01-06-2009)“…The present study demonstrated that the ethyl acetate extract and the isolated compound, parthenolide, from aerial parts of Tanacetum vulgare L. (Asteraceae),…”
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Vitamin K3 induces antiproliferative effect in cervical epithelial cells transformed by HPV 16 (SiHa cells) through the increase in reactive oxygen species production
Published in Archives of gynecology and obstetrics (01-10-2016)“…Purpose Cervical cancer is characterized as an important public health problem. According to latest estimates, cancer of the cervix is the fourth most common…”
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13
Activity of Piperaceae extracts and fractions in the control of Phytomonas serpens
Published in Ciência rural (01-01-2020)“…Protozoa of the genus Phytomonas are harmful parasites to several agricultural crops of economic importance. Due to their recognized biological activity, crude…”
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Chemical Composition and Antimicrobial Properties of Piper ovatum Vahl
Published in Molecules (Basel, Switzerland) (16-03-2009)“…The chemical composition of the essential oil obtained from the leaves of Piperovatum Vahl by hydrodistillation was analyzed by GC-MS. The main constituents…”
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Antiproliferative effect of apocynin in cervical epithelial cells infected by HPV 16 involves change of ROS production and cell cycle
Published in Medicinal chemistry research (01-11-2017)“…The cervical cancer is characterized as a public health problem. The human papillomavirus, especially the high-risk types 16 and 18, is present in 99.7% of…”
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Structure–activity relationship of (−) mammea A/BB derivatives against Leishmania amazonensis
Published in Biomedicine & pharmacotherapy (01-11-2008)“…Abstract To study the structure–activity relationship of coumarin (−) mammea A/BB isolated from the CH2 Cl2 extract of Calophyllum brasiliense leaves, we…”
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Functional mesoporous silica decorated with Ag nanoparticles as chemo-photothermal agents
Published in Microporous and mesoporous materials (01-08-2022)“…This work reports the synthesis, characterization, and evaluation of the photothermal effect of silica-based mesoporous materials (SBA-15), functionalized and…”
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Design and Optimization of Stimuli-responsive Emulsion-filled Gel for Topical Delivery of Copaiba Oil-resin
Published in Journal of pharmaceutical sciences (01-02-2022)“…This study presents a phytotherapeutic emulsion-filled gel design composed of Pluronic® F127, Carbopol® C934P, and high level of copaiba oil-resin (PHY-ECO)…”
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Structural, thermal, optical properties and cytotoxicity of PMMA/ZnO fibers and films: Potential application in tissue engineering
Published in Applied surface science (01-11-2016)“…[Display omitted] •Films and fibers of PMMA/ZnO nanocomposite were prepared.•ZnO NPs incorporated into PMMA fibers reduces their diameter and beads…”
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Ionized alkaline water reduces injury in BALB/c mice infected with Leishmania amazonensis
Published in PloS one (06-07-2023)“…Ionized water has been reported to contribute to the tissue repair process and wound healing. Water purifiers can generate ionized water by means of activated…”
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