Search Results - "Nakamura, Kouki"

Short chain fatty acids produced by Cutibacterium acnes inhibit biofilm formation by Staphylococcus epidermidis by Nakamura, Kouki, O’Neill, Alan M., Williams, Michael R., Cau, Laura, Nakatsuji, Teruaki, Horswill, Alexander R., Gallo, Richard L.

“…Biofilm formation by bacterial pathogens is associated with numerous human diseases and can confer resistance to both antibiotics and host defenses. Many…”
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Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma by Takahashi, Takehiro, Asano, Yoshihide, Sugawara, Koji, Yamashita, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Ichimura, Yohei, Toyama, Tetsuo, Taniguchi, Takashi, Akamata, Kaname, Noda, Shinji, Yoshizaki, Ayumi, Tsuruta, Daisuke, Trojanowska, Maria, Sato, Shinichi

“…Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disorder characterized by vasculopathy and fibrosis in the skin and internal organs, most…”
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Relativistic resistive magneto-hydrodynamics code for high-energy heavy-ion collisions by Nakamura, Kouki, Miyoshi, Takahiro, Nonaka, Chiho, Takahashi, Hiroyuki R.

“…We construct a relativistic resistive magneto-hydrodynamic (RRMHD) numerical simulation code for high-energy heavy-ion collisions as a first designed code in…”
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Contribution of Soluble Forms of Programmed Death 1 and Programmed Death Ligand 2 to Disease Severity and Progression in Systemic Sclerosis by Fukasawa, Takemichi, Yoshizaki, Ayumi, Ebata, Satoshi, Nakamura, Kouki, Saigusa, Ryosuke, Miura, Syunsuke, Yamashita, Takashi, Hirabayashi, Megumi, Ichimura, Yohei, Taniguchi, Takashi, Asano, Yoshihide, Shimizu, Hisashi, Kazoe, Yutaka, Mawatari, Kazuma, Kitamori, Takehiko, Sato, Shinichi

“…Objective To determine the function and serum levels of soluble forms of programmed death 1 (sPD‐1) and one of its ligands, soluble PD ligand 2 (sPD‐L2), in…”
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Charge-dependent anisotropic flow in relativistic resistive magneto-hydrodynamic expansion by Nakamura, Kouki, Miyoshi, Takahiro, Nonaka, Chiho, Takahashi, Hiroyuki

“…We construct a dynamical model for high-energy heavy-ion collisions based on the relativistic resistive magneto-hydrodynamic framework. Using the code, we…”
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Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis by Noda, Shinji, Asano, Yoshihide, Nishimura, Satoshi, Taniguchi, Takashi, Fujiu, Katsuhito, Manabe, Ichiro, Nakamura, Kouki, Yamashita, Takashi, Saigusa, Ryosuke, Akamata, Kaname, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Tsuruta, Daisuke, Trojanowska, Maria, Nagai, Ryozo, Sato, Shinichi

“…Systemic sclerosis (SSc) is manifested by fibrosis, vasculopathy and immune dysregulation. So far, a unifying hypothesis underpinning these pathological events…”
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Lap Joint of 6061 Aluminum Alloy Sheet and DP590 Steel Sheet by Magnetic Pulse Welding and Characterization of Its Interfacial Microstructure by Itoi, Takaomi, Inoue, Shoichi, Nakamura, Kouki, Kitta, Syunichi, Okagawa, Keigo

“…Lap joint sheets of 6061-T6/SPCC and 6061-T6/DP590 (Dual phase) steel were fabricated by magnetic pulse welding (MPW). Strong lap joints were achieved at…”
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Altered Properties of Endothelial Cells and Mesenchymal Stem Cells Underlying the Development of Scleroderma‐like Vasculopathy in KLF5+/−;Fli‐1+/− Mice by Nakamura, Kouki, Taniguchi, Takashi, Hirabayashi, Megumi, Yamashita, Takashi, Saigusa, Ryosuke, Miura, Shunsuke, Takahashi, Takehiro, Toyama, Tetsuo, Ichimura, Yohei, Yoshizaki, Ayumi, Trojanowska, Maria, Fujiu, Katsuhito, Nagai, Ryozo, Sato, Shinichi, Asano, Yoshihide

“…Objective In prevous studies, we established a new animal model, KLF5+/−;Fli‐1+/− mice, in which fundamental pathologic features of systemic sclerosis (SSc)…”
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CXCL13 produced by macrophages due to Fli1 deficiency may contribute to the development of tissue fibrosis, vasculopathy and immune activation in systemic sclerosis by Taniguchi, Takashi, Miyagawa, Takuya, Toyama, Satoshi, Yamashita, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Ichimura, Yohei, Takahashi, Takehiro, Toyama, Tetsuo, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide

“…CXCL13, a chemokine for B cells, follicular T cells, T helper 17 cells, and regulatory T cells, is reported to contribute to the development of systemic…”
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Fli1 deficiency induces endothelial adipsin expression, contributing to the onset of pulmonary arterial hypertension in systemic sclerosis by Miyagawa, Takuya, Taniguchi, Takashi, Saigusa, Ryosuke, Fukayama, Maiko, Takahashi, Takehiro, Yamashita, Takashi, Hirabayashi, Megumi, Miura, Shunsuke, Nakamura, Kouki, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide

“…Abstract Objectives Adipsin, or complement factor D, is a serine proteinase catalysing complement factor C3 breakdown, leading to the production of opsonin…”
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Systemic Sclerosis Dermal Fibroblasts Suppress Th1 Cytokine Production via Galectin-9 Overproduction due to Fli1 Deficiency by Saigusa, Ryosuke, Asano, Yoshihide, Nakamura, Kouki, Hirabayashi, Megumi, Miura, Shunsuke, Yamashita, Takashi, Taniguchi, Takashi, Ichimura, Yohei, Takahashi, Takehiro, Yoshizaki, Ayumi, Miyagaki, Tomomitsu, Sugaya, Makoto, Sato, Shinichi

“…Dermal fibroblasts promote skin-localized transdifferentiation of regulatory T cells to T helper (Th) type 2-like cells in systemic sclerosis (SSc). However,…”
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Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma by Miura, Shunsuke, Watanabe, Yusuke, Saigusa, Ryosuke, Yamashita, Takashi, Nakamura, Kouki, Hirabayashi, Megumi, Miyagawa, Takuya, Yoshizaki, Ayumi, Trojanowska, Maria, Sato, Shinichi, Asano, Yoshihide

“…Aldehyde dehydrogenase 1 family member A1 (RALDH1)-producing dermal dendritic cells (DCs), a conventional DC subset regulating skin fibrosis, are decreased in…”
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Glycyrrhizin Ameliorates Fibrosis, Vasculopathy, and Inflammation in Animal Models of Systemic Sclerosis by Yamashita, Takashi, Asano, Yoshihide, Taniguchi, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Miura, Shunsuke, Toyama, Tetsuo, Takahashi, Takehiro, Ichimura, Yohei, Yoshizaki, Ayumi, Trojanowska, Maria, Sato, Shinichi

“…Systemic sclerosis (SSc) is a multisystem inflammatory and vascular disease resulting in extensive tissue fibrosis. Glycyrrhizin, clinically used for chronic…”
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Fli1 Deficiency Induces CXCL6 Expression in Dermal Fibroblasts and Endothelial Cells, Contributing to the Development of Fibrosis and Vasculopathy in Systemic Sclerosis by Taniguchi, Takashi, Asano, Yoshihide, Nakamura, Kouki, Yamashita, Takashi, Saigusa, Ryosuke, Ichimura, Yohei, Takahashi, Takehiro, Toyama, Tetsuo, Yoshizaki, Ayumi, Sato, Shinichi

“…CXCL6, a chemokine with proangiogenic property, is reported to be involved in vasculopathy associated with systemic sclerosis (SSc). We investigated the…”
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A potential contribution of decreased galectin‐7 expression in stratified epithelia to the development of cutaneous and oesophageal manifestations in systemic sclerosis by Saigusa, Ryosuke, Yamashita, Takashi, Miura, Shunsuke, Hirabayashi, Megumi, Nakamura, Kouki, Miyagawa, Takuya, Fukui, Yuki, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide

“…Backgrounds Stratified epithelia have caught much attention as potential contributors to the development of dermal and oesophageal fibrosis in systemic…”
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Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells by Saigusa, Ryosuke, Asano, Yoshihide, Taniguchi, Takashi, Hirabayashi, Megumi, Nakamura, Kouki, Miura, Shunsuke, Yamashita, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Yoshizaki, Ayumi, Trojanowska, Maria, Sato, Shinichi

“…Friend leukemia virus integration 1 (Fli1) deficiency, a predisposing factor of systemic sclerosis (SSc), induces SSc-like phenotypes in various cell types. A…”
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Serum vasohibin‐1 levels: A potential marker of dermal and pulmonary fibrosis in systemic sclerosis by Fukui, Yuki, Nakamura, Kouki, Hirabayashi, Megumi, Miyagawa, Takuya, Toyama, Satoshi, Omatsu, Jun, Awaji, Kentaro, Ikawa, Tetsuya, Norimatsu, Yuta, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide

“…Vasohibin‐1 (VASH‐1) is a potent anti‐angiogenic factor mainly produced by endothelial cells. In addition, VASH‐1 prevents TGF‐β–dependent activation of renal…”
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Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis by Akamata, Kaname, Asano, Yoshihide, Taniguchi, Takashi, Yamashita, Takashi, Saigusa, Ryosuke, Nakamura, Kouki, Noda, Shinji, Aozasa, Naohiko, Toyama, Tetsuo, Takahashi, Takehiro, Ichimura, Yohei, Sumida, Hayakazu, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi

“…Chemerin is a member of adipocytokines with a chemoattractant effect on plasmacytoid dendritic cells and macrophages and pro-angiogenic properties. We…”
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Degree of Alignment Between Japanese Patients and Physicians on Alopecia Areata Disease Severity and Treatment Satisfaction: A Real-World Survey by Nakamura, Kouki, Kamei, Kazumasa, Austin, Jenny, Marwaha, Simran, Piercy, James, Anderson, Peter, Sakaki-Yumoto, Masayo, Ohyama, Manabu

“…Introduction Alopecia areata (AA) is characterized by non-scarring scalp and/or body hair loss and can negatively impact patient mental health. Data are…”
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The impact of transcription factor Fli1 deficiency on the regulation of angiogenesis by Toyama, Tetsuo, Asano, Yoshihide, Miyagawa, Takuya, Nakamura, Kouki, Hirabayashi, Megumi, Yamashita, Takashi, Saigusa, Ryosuke, Miura, Shunsuke, Ichimura, Yohei, Takahashi, Takehiro, Taniguchi, Takashi, Yoshizaki, Ayumi, Sato, Shinichi

“…The insufficiency of Friend leukaemia virus integration 1 (Fli1), a member of the Ets family transcription factors, is implicated in the pathogenesis of…”
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