Search Results - "Nakamoto, Meagan"

Nonspecific Binding of RNA to PARP1 and PARP2 Does Not Lead to Catalytic Activation by Nakamoto, Meagan Y, Rudolph, Johannes, Wuttke, Deborah S, Luger, Karolin

“…Poly­(ADP-ribose) polymerases 1 and 2 (PARP1 and PARP2, respectively), upon binding damaged DNA, become activated to add long chains of poly­(ADP-ribose) (PAR)…”
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hnRNPK recognition of the B motif of Xist and other biological RNAs by Nakamoto, Meagan Y, Lammer, Nickolaus C, Batey, Robert T, Wuttke, Deborah S

“…Heterogeneous nuclear ribonuclear protein K (hnRNPK) is an abundant RNA-binding protein crucial for a wide variety of biological processes. While its binding…”
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Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation by Carter, Ava C, Xu, Jin, Nakamoto, Meagan Y, Wei, Yuning, Zarnegar, Brian J, Shi, Quanming, Broughton, James P, Ransom, Ryan C, Salhotra, Ankit, Nagaraja, Surya D, Li, Rui, Dou, Diana R, Yost, Kathryn E, Cho, Seung-Woo, Mistry, Anil, Longaker, Michael T, Khavari, Paul A, Batey, Robert T, Wuttke, Deborah S, Chang, Howard Y

“…The lncRNA mediates X chromosome inactivation (XCI). Here we show that Spen, an -binding repressor protein essential for XCI , binds to ancient retroviral RNA,…”
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Structural and Functional Effects of Cu Metalloprotein-Driven Silver Nanoparticle Dissolution by Martinolich, Andrew J, Park, Grace, Nakamoto, Meagan Y, Gate, Rachel E, Wheeler, Korin E

“…Interactions of a model Cu-metalloprotein, azurin, with 10–100 nm silver nanoparticles (NPs) were examined to elucidate the role of oxidative dissolution and…”
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Non-specific binding of RNA to PARP1 and PARP2 does not lead to catalytic activation by Nakamoto, Meagan Y., Rudolph, Johannes, Wuttke, Deborah S., Luger, Karolin

“…Poly-(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2), upon binding damaged DNA, become activated to add long chains of poly-(ADP-ribose) (PAR) to themselves…”
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Molecular Recognition Underlying X Chromosome Inactivation: Interactions Between hnRnpk and Spen with Different Regions of Xist by Nakamoto, Meagan Y

“…X chromosome inactivation (XCI) is a developmental process in which mammalian females transcriptionally silence one of their two X chromosomes to achieve gene…”
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Abstract 2780: Unique pharmacodynamic properties conferred by differential binding to BTK, pirtobrutinib vs covalent inhibitors by Ballard, Joshua A., Ebata, Kevin, Randeria, Hetal S., Tinline, Garrett, Lee, Thomas, Hanson, Lauren M., Latham, John A., Cedervall, E. Peder, Chong, Jenny, Valle, Kyle B. Del, Collins, Bernard C., Morales, Tony H., Benedict, Thomas C., Schureck, Marc A., Bender, Ethan T., Mendoza, Christopher, Molina, David, Nakamoto, Meagan, Shiah, Hsiao-Chiao, Xu, Hao, Espada, Alfonso, Cano, Leticia, Allerston, Charles K., Schnier, Paul, Brandhuber, Barbara J.

“…Abstract Covalent Bruton tyrosine kinase inhibitors (cBTKi) have transformed the treatment of B cell malignancies. Despite the efficacy of cBTKi, treatment…”
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