Search Results - "Nakamaru, Kazuhiko"
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Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression
Published in Circulation research (14-10-2005)“…Vascular smooth muscle cell (VSMC) proliferation is a critical event in the development and progression of vascular diseases, including atherosclerosis. We…”
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AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells
Published in Biochemical and biophysical research communications (11-03-2005)“…The liver is one of the major target organs of insulin in which the expression of insulin receptor is abundant. We analyzed the effect of AICAR, an AMPK…”
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A Case of ACTH-Independent Macronodular Adrenal Hyperplasia: Simultaneous Expression of Several Aberrant Hormone Receptors in the Adrenal Gland
Published in ENDOCRINE JOURNAL (2003)“…ACTH-independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of Cushing’s syndrome. Recently, aberrant expression of adrenal receptors for various…”
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Regulation of the Insulin Gene Transcription by Glucose
Published in ENDOCRINE JOURNAL (2002)“…BETA cells in the pancreatic islet synthesize and secrete insulin, the key hormone involved in glucose homeostasis. Impaired insulin secretion and/or impaired…”
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Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells
Published in Biochemical and biophysical research communications (03-01-2003)“…Pancreatic β-cells exposed to hyperglycemia produce reactive oxygen species (ROS). Because β-cells are sensitive to oxidative stress, excessive ROS may cause…”
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Possible Involvement of AMPK in AICAR-Induced Down-Regulation of Insulin Receptor Expression in HepG2 Cells
Published in Diabetes (New York, N.Y.) (01-06-2005)Get full text
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Preclinical Cushing's syndrome resulting from black adrenal adenoma. A case report
Published in Hormone research (01-01-2004)“…A 59-year-old Japanese woman, admitted for the treatment of diabetes mellitus and hypertension, was incidentally discovered to have a solid mass of 1.4 cm in…”
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