Search Results - "Nakajima, Masato"

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis by Nagahashi, Masayuki, Yamada, Akimitsu, Katsuta, Eriko, Aoyagi, Tomoyoshi, Huang, Wei-Ching, Terracina, Krista P, Hait, Nitai C, Allegood, Jeremy C, Tsuchida, Junko, Yuza, Kizuki, Nakajima, Masato, Abe, Manabu, Sakimura, Kenji, Milstien, Sheldon, Wakai, Toshifumi, Spiegel, Sarah, Takabe, Kazuaki

“…Although obesity with associated inflammation is now recognized as a risk factor for breast cancer and distant metastases, the functional basis for these…”
Get full text

Scanning ion conductance microscopy for visualizing the three-dimensional surface topography of cells and tissues by Nakajima, Masato, Mizutani, Yusuke, Iwata, Futoshi, Ushiki, Tatsuo

“…Scanning ion conductance microscopy (SICM), which belongs to the family of scanning probe microscopy, regulates the tip-sample distance by monitoring the ion…”
Get full text

Scanning ion conductance microscopy of isolated metaphase chromosomes in a liquid environment by Ushiki, Tatsuo, Ishizaki, Kimihiro, Mizutani, Yusuke, Nakajima, Masato, Iwata, Futoshi

“…Scanning probe microscopy (SPM) uses a probing tip which scans over a sample surface for obtaining information on the sample surface characteristics. Among…”
Get full text

The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases by Nagahashi, Masayuki, Yuza, Kizuki, Hirose, Yuki, Nakajima, Masato, Ramanathan, Rajesh, Hait, Nitai C., Hylemon, Phillip B., Zhou, Huiping, Takabe, Kazuaki, Wakai, Toshifumi

“…Based on research carried out over the last decade, it has become increasingly evident that bile acids act not only as detergents, but also as important…”
Get full text

Activin a Receptor Type 2A Mutation Affects the Tumor Biology of Microsatellite Instability-High Gastric Cancer by Yuza, Kizuki, Nagahashi, Masayuki, Ichikawa, Hiroshi, Hanyu, Takaaki, Nakajima, Masato, Shimada, Yoshifumi, Ishikawa, Takashi, Sakata, Jun, Takeuchi, Shiho, Okuda, Shujiro, Matsuda, Yasunobu, Abe, Manabu, Sakimura, Kenji, Takabe, Kazuaki, Wakai, Toshifumi

“…Background Activin A receptor type 2A ( ACVR2A ) is one of the most frequently mutated genes in microsatellite instability-high (MSI-H) gastric cancer…”
Get full text

In vitro regulation of circadian phosphorylation rhythm of cyanobacterial clock protein KaiC by KaiA and KaiB by Nakajima, Masato, Ito, Hiroshi, Kondo, Takao

“…Biochemical circadian oscillation of KaiC phosphorylation, by mixing three Kai proteins and ATP, has been proven to be the central oscillator of the…”
Get full text

Reconstitution of Circadian Oscillation of Cyanobacterial KaiC Phosphorylation in Vitro by Nakajima, Masato, Imai, Keiko, Ito, Hiroshi, Nishiwaki, Taeko, Murayama, Yoriko, Iwasaki, Hideo, Oyama, Tokitaka, Kondo, Takao

“…Kai proteins globally regulate circadian gene expression of cyanobacteria. The KaiC phosphorylation cycle, which persists even without transcription or…”
Get full text

Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer by Yuza, Kizuki, Nagahashi, Masayuki, Shimada, Yoshifumi, Nakano, Mae, Tajima, Yosuke, Kameyama, Hitoshi, Nakajima, Masato, Takabe, Kazuaki, Wakai, Toshifumi

“…Colitis-associated cancer (CAC) is the most serious complication of inflammatory bowel disease. Sphingosine-1-phosphate (S1P) is a bioactive lipid mediator…”
Get full text

The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications by Nakajima, Masato, Nagahashi, Masayuki, Rashid, Omar M, Takabe, Kazuaki, Wakai, Toshifumi

“…Elucidating the interaction between cancer and non-cancer cells, such as blood vessels, immune cells, and other stromal cells, in the tumor microenvironment is…”
Get full text

Cyanobacterial Circadian Pacemaker: Kai Protein Complex Dynamics in the KaiC Phosphorylation Cycle In Vitro by Kageyama, Hakuto, Nishiwaki, Taeko, Nakajima, Masato, Iwasaki, Hideo, Oyama, Tokitaka, Kondo, Takao

“…KaiA, KaiB, and KaiC are essential proteins of the circadian clock in the cyanobacterium Synechococcus elongatus PCC 7942. The phosphorylation cycle of KaiC…”
Get full text

Association between oral candidiasis and bacterial pneumonia: A retrospective study by Nakajima, Masato, Umezaki, Yojiro, Takeda, Satoshi, Yamaguchi, Masahiro, Suzuki, Nao, Yoneda, Masahiro, Hirofuji, Takao, Sekitani, Hiroko, Yamashita, Yuichi, Morita, Hiromitsu

“…Objective To investigate associated risk factors for oral candidiasis in elderly patients hospitalized in a community‐based acute‐care hospital with no dental…”
Get full text

Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression by Yuza, Kizuki, Nakajima, Masato, Nagahashi, Masayuki, Tsuchida, Junko, Hirose, Yuki, Miura, Kohei, Tajima, Yosuke, Abe, Manabu, Sakimura, Kenji, Takabe, Kazuaki, Wakai, Toshifumi

“…Pancreatic cancer is a disease with poor prognosis, and development of new treatments is necessary. Sphingosine-1-phosphate (S1P), a bioactive lipid mediator…”
Get full text

CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock by Isojima, Yasushi, Nakajima, Masato, Ukai, Hideki, Fujishima, Hiroshi, Yamada, Rikuhiro G, Masumoto, Koh-hei, Kiuchi, Reiko, Ishida, Mayumi, Ukai-Tadenuma, Maki, Minami, Yoichi, Kito, Ryotaku, Nakao, Kazuki, Kishimoto, Wataru, Yoo, Seung-Hee, Shimomura, Kazuhiro, Takao, Toshifumi, Takano, Atsuko, Kojima, Toshio, Nagai, Katsuya, Sakaki, Yoshiyuki, Takahashi, Joseph S, Ueda, Hiroki R

“…A striking feature of the circadian clock is its flexible yet robust response to various environmental conditions. To analyze the biochemical processes…”
Get full text

Reduction of translation rate stabilizes circadian rhythm and reduces the magnitude of phase shift by Nakajima, Masato, Koinuma, Satoshi, Shigeyoshi, Yasufumi

“…In the intracellular environment, the circadian oscillator is exposed to molecular noise. Nevertheless, cellular rhythms are robust and show almost constant…”
Get full text

A KaiC-Associating SasA-RpaA Two-Component Regulatory System as a Major Circadian Timing Mediator in Cyanobacteria by Takai, Naoki, Nakajima, Masato, Oyama, Tokitaka, Kito, Ryotaku, Sugita, Chieko, Sugita, Mamoru, Kondo, Takao, Iwasaki, Hideo

“…KaiA, KaiB, and KaiC clock proteins from cyanobacteria and ATP are sufficient to reconstitute the KaiC phosphorylation rhythm in vitro, whereas almost all gene…”
Get full text

Spontaneous Renal Artery Dissection in a Man with Previous Spontaneous Superior Mesenteric Artery Dissection by Yokoyama, Yujiro, Nakajima, Masato

“…Both spontaneous superior mesenteric artery dissection (SMAD) and spontaneous renal artery dissection (SRAD) are very rare conditions. Their etiologies and…”
Get full text

Autonomous synchronization of the circadian KaiC phosphorylation rhythm by Oyama, Tokitaka, Kondo, Takao, Ito, Hiroshi, Kageyama, Hakuto, Mutsuda, Michinori, Nakajima, Masato

“…The cyanobacterial circadian oscillator can be reconstituted in vitro by mixing three purified clock proteins, KaiA, KaiB and KaiC, with ATP. The KaiC…”
Get full text

Swelling and Salt Formation in Ibuprofen and Tranexamic Acid-Containing Tablets during High-Temperature Storage by Kawano, Yuto, Tanaka, Yoshiharu, Hata, Nanami, Yoshiike, Yuki, Nakajima, Masato, Yonemochi, Etsuo, Ishihara, Nobuhiro

“…Ibuprofen (IBP)- and Tranexamic acid (TXA)-containing tablets are known to swell when stored at high temperatures, but the mechanism of swelling is unknown. In…”
Get full text

Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients by Nagahashi, Masayuki, Ling, YiWei, Toshikawa, Chie, Hayashida, Tetsu, Kitagawa, Yuko, Futamura, Manabu, Kuwayama, Takashi, Nakamura, Seigo, Yamauchi, Hideko, Yamauchi, Teruo, Kaneko, Koji, Kanbayashi, Chizuko, Sato, Nobuaki, Tsuchida, Junko, Moro, Kazuki, Nakajima, Masato, Shimada, Yoshifumi, Ichikawa, Hiroshi, Lyle, Stephen, Miyoshi, Yasuo, Takabe, Kazuaki, Okuda, Shujiro, Wakai, Toshifumi

“…Background Next-generation sequencing (NGS) has enabled comprehensive genomic profiling to identify gene alterations that play important roles in cancer…”
Get full text

KaiA-Stimulated KaiC Phosphorylation in Circadian Timing Loops in Cyanobacteria by Iwasaki, Hideo, Nishiwaki, Taeko, Kitayama, Yohko, Nakajima, Masato, Kondo, Takao

“…Cyanobacterial clock proteins KaiA and KaiC are proposed as positive and negative regulators in the autoregulatory circadian kaiBC expression, respectively…”
Get full text