Search Results - "Nakaike, S"

Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis by Takaoka, A., Arai, I., Sugimoto, M., Honma, Y., Futaki, N., Nakamura, A., Nakaike, S.

“…:  Pruritus is an important symptom in atopic dermatitis (AD), but the major pruritogen have not been identified. NC/Nga mice, spontaneously develop an…”
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Induction of scratching behaviour and dermatitis in various strains of mice cohabiting with NC/Nga mice with chronic dermatitis by Hashimoto, Y., Arai, I., Takano, N., Tanaka, M., Nakaike, S.

“…Summary Background  NC/Nga (NC) mice with similar pathological and behavioural features as seen in human atopic dermatitis are used as a model of the disease…”
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Role of COX-1 and COX-2 on skin PGs biosynthesis by mechanical scratching in mice by Sugimoto, M., Arai, I., Futaki, N., Hashimoto, Y., Honma, Y., Nakaike, S.

“…We examined the involvement of cyclooxygenase (COX)-1 and COX-2 on mechanical scratching-induced prostaglandins (PGs) production in the skin of mice. The…”
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Scratching behavior in spontaneous- or allergic contact-induced dermatitis in NC/Nga mice by Takahashi, N., Arai, Iwao, Honma, Y., Hashimoto, Y., Harada, M., Futaki, N., Sugimoto, M., Nakaike, S.

“…:  NC/Nga mice have pathological and behavioral features similar to those seen in human atopic dermatitis. There are two known dermatitis models in NC/Nga…”
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Cyclooxygenase-1 inhibition delays recovery of the cutaneous barrier disruption caused by mechanical scratching in mice by Honma, Y., Arai, I., Futaki, N., Hashimoto, Y., Sugimoto, M., Sakurai, T., Nakaike, S.

“…Summary Background  Atopic dermatitis is a chronic inflammatory disease characterized by severe pruritus, and cutaneous barrier disruption by scratching…”
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Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus by Yoshida, S, Maeda, M, Kaku, S, Ikeya, H, Yamada, K, Nakaike, S

“…It has been pointed out that hyperphosphorylation of microtubule-associated protein tau caused by stress might participate in the early stages of Alzheimer's…”
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Role of prostaglandins on mechanical scratching-induced cutaneous barrier disruption in mice by Futaki, N., Arai, I., Sugimoto, M., Honma, Y., Hashimoto, Y., Sakurai, T., Nakanishi, Y., Tanaka, M., Nakaike, S.

“…:  The role of prostaglandins (PGs) on mechanical scratching‐induced cutaneous barrier disruption in mice was investigated by comparing the observed effects of…”
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Increased scratching counts depend on a decrease in ability of cutaneous prostaglandin D2 biosynthesis in NC/Nga mice with atopic dermatitis by Sugimoto, M., Arai, I., Futaki, N., Hashimoto, Y., Honma, Y., Nakaike, S.

“…:  Spontaneous and 2,4,6‐trinitrochlorobenzene (TNCB)‐induced dermatitis models using NC/Nga mice have been recognized as animal models of atopic dermatitis…”
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Increased scratching counts depend on a decrease in ability of cutaneous prostaglandin D 2 biosynthesis in NC/Nga mice with atopic dermatitis by Sugimoto, M., Arai, I., Futaki, N., Hashimoto, Y., Honma, Y., Nakaike, S.

“…Spontaneous and 2,4,6‐trinitrochlorobenzene (TNCB)‐induced dermatitis models using NC/Nga mice have been recognized as animal models of atopic dermatitis. We…”
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A Critical Role for Mouse CXC Chemokine(s) in Pulmonary Neutrophilia During Th Type 1-Dependent Airway Inflammation by Takaoka, Akiko, Tanaka, Yoshitaka, Tsuji, Takemasa, Jinushi, Takafumi, Hoshino, Akihiko, Asakura, Yumiko, Mita, Yasuo, Watanabe, Kazuhito, Nakaike, Shiro, Togashi, Yuji, Koda, Toshiaki, Matsushima, Kouji, Nishimura, Takashi

“…Ag-specific Th1 and Th2 cells have been demonstrated to play a critical role in the induction of allergic diseases. Here we have investigated the precise…”
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Side Chain-Dependent Binding of Antitumor Indoloquinoxaline Derivatives to DNA: Comparative Spectroscopic and Viscometric Measurements by HIRATA, Kazumi, ARAYA, Jyunko, NAKAIKE, Shiro, KITAMURA, Kunihiro, ISHIDA, Toshimasa

“…NCA0424 (1) and its side chain positional isomer, NCA0465 (2), are indoloquinoxaline derivatives with potent antitumor activity. To investigate the effect of…”
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DNA-binding characterization of a novel anti-tumour benzo[a]phenazine derivative NC-182: spectroscopic and viscometric studies by Tarui, M, Doi, M, Ishida, T, Inoue, M, Nakaike, S, Kitamura, K

“…NC-182 is a novel anti-tumour compound having a benzo[a]phenazine ring. Fluorescence, absorption and c.d. spectroscopy, as well as viscometric titrations, were…”
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High-pressure synthesis and magnetic properties of C14-TbMn2 by Endo, S., Nakaike, S., Ishizuka, M., Ono, F.

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Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis by Takaoka, Akiko, Arai, Iwao, Sugimoto, Masanori, Yamaguchi, Akie, Tanaka, Makoto, Nakaike, Shiro

“…To search for the pruritogen of atopic dermatitis, a characteristic symptom in atopic dermatitis patients, we examined interleukin-31 (IL-31) mRNA expression…”
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KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line by Sugimoto, M, Inoue, T, Yamashita, M, Takeshita, K, Nakaike, S

“…KE-758, an active metabolite of KE-298, is a novel sulfhydryl antirheumatic drug. We analyzed the effect of KE-758 on tumor necrosis factor (TNF)-alpha and…”
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High-pressure effects in SiAsTe amorphous chalcogenide glasses fabricated under microgravity environment by Shams-Kolahi, Wahid, Endo, Shoichi, Kobayashi, Yuki, Honda, A., Nakaike, S., Toma, T., Hambach, M., Takeshima, S., Okamoto, Hiroaki, Hamakawa, Yoshihiro

“…The effect of high pressure on electrical properties has been investigated for two sets of Si 9As 14Te 21 ternary chalcogenide amorphous semiconductor samples,…”
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Scratching of their skin by NC/Nga mice leads to development of dermatitis by Hashimoto, Yuki, Arai, Iwao, Nakanishi, Yutaka, Sakurai, Takanobu, Nakamura, Atsushi, Nakaike, Shiro

“…Effects of scratching behavior on dermatitis, transepidermal water loss (TEWL) and serum IgE concentrations were examined in NC/Nga (NC) mice with toenails…”
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Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma by Hoshino, Akihiko, Tanaka, Yoshitaka, Akiba, Hisaya, Asakura, Yumiko, Mita, Yasuo, Sakurai, Takanobu, Takaoka, Akiko, Nakaike, Shiro, Ishii, Naoto, Sugamura, Kazuo, Yagita, Hideo, Okumura, Ko

“…Bronchial asthma is characterized by massive infiltration of eosinophils and airway hyperreactivity (AHR), which are caused by overproduction of Th2 cytokines…”
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Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury by OMURA, Tomohiro, TANAKA, Yu, NAKAIKE, Shiro, OKUYAMA, Shigeru, HARDER, Phi David R, ROMAN, Richard J, MIYATA, Noriyuki, KOIZUMI, Chie, SAKURAI, Takanobu, FUKASAWA, Misako, HACHIUMA, Kenji, MINAGAWA, Toshiya, SUSUMU, Teruo, YOSHIDA, Shigeru

“…Arachidonic acid that is released following cerebral ischemia can be metabolized to 20-hydroxyeicosatetraenoic acid (20-HETE). 20-HETE is a potent…”
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Prostaglandin D 2 and prostaglandin E 2 accelerate the recovery of cutaneous barrier disruption induced by mechanical scratching in mice by Honma, Yusuke, Arai, Iwao, Hashimoto, Yuki, Futaki, Nobuko, Sugimoto, Masanori, Tanaka, Makoto, Nakaike, Shiro

“…The role of prostaglandins in mechanical scratching-induced cutaneous barrier disruption in mice was investigated. Skin prostaglandins contents were measured…”
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