Search Results - "Nakahara, Jin"
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Visualization of Myelin for the Diagnosis and Treatment Monitoring of Multiple Sclerosis
Published in Advances in experimental medicine and biology (2019)“…Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) affecting more than two million people worldwide. As the exact etiology…”
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Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2016)“…ObjectiveTo elucidate the common and distinct clinical features of immune-mediated necrotising myopathy (IMNM), also known as necrotising autoimmune myopathy…”
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3
Electroconvulsive Therapy for Parkinson's Disease: A Systematic Review and Meta‐Analysis
Published in Movement disorders (01-01-2021)“…Background Electroconvulsive therapy (ECT) is a well‐established treatment for psychiatric disorders, including depression and psychosis. ECT has been reported…”
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The Early Onset of Levodopa-induced Dyskinesia in a Patient with Multiple System Atrophy
Published in Internal Medicine (01-09-2024)“…Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by Parkinsonism, cerebellar ataxia, and autonomic dysfunction. While less frequent…”
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Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
Published in Nature neuroscience (01-09-2020)“…The chemogenetic technology designer receptors exclusively activated by designer drugs (DREADDs) afford remotely reversible control of cellular signaling,…”
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Maiden voyage: induced pluripotent stem cell-based drug screening for amyotrophic lateral sclerosis
Published in Brain (London, England : 1878) (05-01-2023)“…Using patient-derived induced pluripotent stem cells, neurodegenerative disease phenotypes have been recapitulated and their pathogenesis analysed leading to…”
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Anemia in female patients with myasthenia gravis
Published in PloS one (06-09-2022)“…Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder, and is more common in women than in men. Anemia is also more common in women. The…”
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Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice
Published in Brain research (01-10-2022)“…[Display omitted] •No infarct was detected in mice without SD during experimental ischemia.•The infarct size tended to be larger in repeated SD-occurred…”
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Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice
Published in International journal of molecular sciences (09-11-2022)“…Goreisan, a traditional Japanese Kampo medicine, is often used to treat headaches, including migraines; however, the underlying mechanisms remain unknown…”
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Neuroimaging pattern and pathophysiology of cerebellar stroke-like lesions in MELAS with m.3243A>G mutation: a case report
Published in BMC neurology (01-05-2020)“…Stroke-like episodes (SLEs) in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with m.3243A > G mutation usually…”
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Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study
Published in Journal of headache and pain (09-03-2023)“…Background Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) are a favourable option for patients with migraine who experience distressful…”
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Clinically feasible novel magnetic resonance imaging modality for the visualization of myelin in the central nervous system
Published in Clinical & experimental neuroimmunology (01-08-2016)“…We have successfully developed a new magnetic resonance imaging modality named “q‐space Myelin Map” to visualize myelin within the central nervous system. The…”
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13
Painless Thyroiditis Presenting with Headache
Published in Internal Medicine (15-08-2021)“…Although headache attributed to hypothyroidism is coded within The International Classification of Headache Disorders, 3rd edition, an association between…”
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Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant
Published in Scientific reports (10-07-2020)“…Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia,…”
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Sustained Effects of CGRP Blockade on Cortical Spreading Depolarization-Induced Alterations in Facial Heat Pain Threshold, Light Aversiveness, and Locomotive Activity in the Light Environment
Published in International journal of molecular sciences (09-11-2022)“…A migraine is clinically characterized by repeated headache attacks that entail considerable disability. Many patients with migraines experience postdrome, the…”
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Calcitonin Gene-Related Peptide mRNA Synthesis in Trigeminal Ganglion Neurons after Cortical Spreading Depolarization
Published in International journal of molecular sciences (01-07-2023)“…Migraine is a debilitating neurovascular disorder characterized by recurrent headache attacks of moderate to severe intensity. Calcitonin gene-related peptide…”
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Primary Progressive Multiple Sclerosis
Published in Brain and nerve = Shinkei kenkyū no shinpo (01-05-2021)“…Primary progressive multiple sclerosis (PPMS) is a chronic inflammatory disease of the central nervous system that leads to demyelination and…”
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Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons
Published in Journal of cerebral blood flow and metabolism (01-10-2021)“…A variety of brain cells participates in neurovascular coupling by transmitting and modulating vasoactive signals. The present study aimed to probe cell…”
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Polyradiculoneuropathy induced by immune checkpoint inhibitors: a case series and review of the literature
Published in Journal of neurology (01-02-2021)“…Objective The purpose of the present study is to report the clinical characteristics of polyradiculoneuropathy induced by immune checkpoint inhibitors (ICIs)…”
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Cerebral Venous Thrombosis Mimicking Limbic Encephalitis
Published in Internal Medicine (01-05-2024)“…Cerebral venous thrombosis (CVT) is challenging to diagnose, as it presents with variable symptoms. We encountered a complicated case of CVT that mimicked…”
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