Brazilian consensus on the diagnosis and treatment of extremities soft tissue sarcomas

Introduction Soft tissue sarcomas (STSs) are rare tumors and constitute only 1% of all tumors in adults. Indeed, due to their rarity, most cases in Brazil are not treated according to primary international guidelines. Methods This consensus addresses the treatment of STSs in the extremities. It was...

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Bibliographic Details
Published in:	Journal of surgical oncology Vol. 121; no. 5; pp. 743 - 758
Main Authors:	Spencer, Ranyell M. S. S. B., Camargo, Veridiana P., Silva, Maria L. G., Pinto, Fabio F. E., Costa, Felipe D'Almeida, Cequeira, Wagner S., Munhoz, Rodrigo R., Mello, Celso A., Schmerling, Rafael A., Filho, Waldec J. D., Coelho, Tharcisio M., Ambrosio, Alexandre V. A., Leite, Elton T. T., Hanna, Samir A., Nakagawa, Sueli A., Baptista, Andre M., Pinheiro, Rodrigo N., Oliveira, Jadivan L., Araújo, Marcelo Sá, Araujo, Raphael L. C., Laporte, Gustavo A., Almeida Quadros, Claudio, Oliveira, Alexandre F., Lopes, Ademar
Format:	Journal Article Conference Proceeding
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-04-2020
Subjects:	Biopsy Brazil Cancer therapies Chemotherapy, Adjuvant Extremities - pathology Extremities - surgery Gastrointestinal cancer Humans Lymph Nodes - pathology multidisciplinary sarcoma Neoplasm Metastasis - diagnosis Neoplasm Metastasis - therapy Neoplasm Staging Oncology Palliative Care Postoperative Complications - therapy Radiotherapy, Adjuvant Risk Factors Sarcoma Sarcoma - diagnostic imaging Sarcoma - pathology Sarcoma - therapy sarcoma consensus sarcoma reference cancer centers Soft Tissue Neoplasms - diagnostic imaging Soft Tissue Neoplasms - pathology Soft Tissue Neoplasms - therapy soft tissue sarcomas Tumors Brazil soft tissue sarcomas multidisciplinary sarcoma sarcoma reference cancer centers sarcoma consensus
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Summary:	Introduction Soft tissue sarcomas (STSs) are rare tumors and constitute only 1% of all tumors in adults. Indeed, due to their rarity, most cases in Brazil are not treated according to primary international guidelines. Methods This consensus addresses the treatment of STSs in the extremities. It was made by workgroups from Brazilian Societies of Surgical Oncology, Orthopaedics, Clinical Oncology, Pathology, Radiology and Diagnostic Imaging, and Radiation Oncology. The workgroups based their arguments on the best level of evidence in the literature and recommendations were made according to diagnosis, staging, and treatment of STSs. A meeting was held with all the invited experts and the topics were presented individually with the definition of the degree of recommendation, based on the levels of evidence in the literature. Results Risk factors and epidemiology were described as well as the pathological aspects and imaging. All recommendations are described with the degree of recommendation and levels of evidence. Conclusion Recommendations based on the best literature regional aspects were made to guide professionals who treat STS. Separate consensus on specific treatments for retroperitoneal, visceral, trunk, head and neck sarcomas, and gastrointestinal stromal tumor, are not contemplated into this consensus.
Bibliography:	ObjectType-News-1 content type line 25 ObjectType-Feature-4 ObjectType-Conference-2 SourceType-Conference Papers & Proceedings-1 ObjectType-Article-3
ISSN:	0022-4790 1096-9098
DOI:	10.1002/jso.25847