Search Results - "Najmi, A. K."

Okadaic acid-induced Tau phosphorylation in rat brain: Role of NMDA receptor by Kamat, P.K, Rai, S, Swarnkar, S, Shukla, R, Ali, S, Najmi, A.K, Nath, C

“…Highlights ► Intracerebroventricular (ICV) administration of OKA causes memory impairment in rats. ► The OKA induces decrease in PP-2A activity which leads to…”
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Rosuvastatin ameliorates cognitive impairment in rats fed with high-salt and cholesterol diet via inhibiting acetylcholinesterase activity and amyloid beta peptide aggregation by Husain, I, Akhtar, M, Abdin, M Zainul, Islamuddin, M, Shaharyar, M, Najmi, A K

“…Amyloid beta (Aβ) peptide aggregation and cholinergic neurodegeneration are involved in the development of cognitive impairment. Therefore, in this article, we…”
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Differential effect of p38 and MK2 kinase inhibitors on the inflammatory and toxicity biomarkers in vitro by Singh, R K, Diwan, M, Dastidar, S G, Najmi, A K

“…Many inflammatory responses including chemotaxis, production of nitric oxide, and modulation of pro-inflammatory cytokines in immunological cells are mediated…”
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Effect of zinc in animal models of anxiety, depression and psychosis by Joshi, M, Akhtar, M, Najmi, A K, Khuroo, A H, Goswami, D

“…The role of zinc (Zn) in anxiety, depression and psychosis was studied in rodents. Zn was administered at doses of 15 and 20 mg/kg intraperitoneally for 7…”
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Protective Effect of Irbesartan an Angiotensin (AT1) Receptor Antagonist in Unpredictable Chronic Mild Stress Induced Depression in Mice by Ayyub, M, Najmi, A K, Akhtar, M

“…Oxidative stress and alternation of renin-angiotensin system has been implicated in the pathophysiology of various cardio vascular, endocrine including mood…”
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Antidepressant Effect of Thymoquinone in Animal Models of Depression by Aquib, M, Najmi, A K, Akhtar, M

“…The present study was carried out to determine the role of thymoquinone (TQ) in modulating the levels of neurotransmitter and reducing the oxidative stress in…”
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Synthesis, in-Silico studies and biological evaluation of pyrimidine based thiazolidinedione derivatives as potential anti-diabetic agent by Amin, Shaista, Sheikh, Khursheed A, Iqubal, Ashif, Ahmed Khan, Mohammad, Shaquiquzzaman, M., Tasneem, Sharba, Khanna, Suruchi, Najmi, A.K., Akhter, Mymoona, Haque, Anzarul, Anwer, Tarique, Mumtaz Alam, M.

“…[Display omitted] •A novel series of pyrimidine-thiazolidinedione derivatives was synthesized.•In-silico molecular docking and ADME evaluation using…”
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A review on synthetic procedures and applications of phosphorus oxychloride (POCl3) in the last biennial period (2018-19) by Amin, Shaista, Alam, M. Mumtaz, Akhter, Mymoona, Najmi, A. K., Siddiqui, Nadeem, Husain, Asif, Shaquiquzzaman, M.

“…Phosphorus oxychloride, POCl 3 , an important phosphorus compound, has diverse applications in synthetic chemistry. It plays an important role in chlorination,…”
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Monoterpene phenolic compound thymol prevents high fat diet induced obesity in murine model by Haque, Mohammad Rafiul, Ansari, S. H., Najmi, A. K., Ahmad, Mohammed Afroz

“…Abstract Context: Obesity has become a worldwide health problem. Most of the synthetic anti-obesity drugs have failed to manage the obesity due to either…”
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Neuropharmacological safety evaluation of jigrine: A polyherbal hepatoprotective formulation by Najmi, A K, Pillai, K K, Pal, S N, Akhtar, M, Mujeeb, M, Aftab, A

“…Jigrine is a herbal hepatoprotective formulation containing aqueous extracts of 14 medicinal plants. Present study was designed to evaluate per se…”
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Protective Effect of Guggulipid in High Fat Diet and Middle Cerebral Artery Occlusion (MCAO) Induced Ischemic Cerebral Injury in Rats by Ahmad, M A, Najmi, A K, Mujeeb, M, Akhtar, M

“…The role of guggulipid was evaluated in high fat diet and middle cerebral artery occlusion (MCAO) induced ischemic cerebral dysfunctions in rats of either sex…”
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Effect of Sarcosine (a Glycine Transport 1 Inhibitor) and Risperidone (an Atypical antipsychotic Drug) on MK-801 Induced Learning and Memory Deficits in Rats by Kumar, V, Ahmad, M A, Najmi, A K, Akhtar, M

“…The present study was carried out to evaluate whether the combined administration of sarcosine with risperidone possess any advantageous effects on…”
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A prospective research study of anti-glaucoma drugs prescribing, utilization pattern and adverse drug reaction recording in a university hospital by Alaei, M, Najmi, A K, Kausar, H, Akhtar, M

“…This study was carried out to evaluate the drug prescribing, utilization pattern and adverse drug reactions recording associated with drugs prescribed to…”
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Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats by Hass, C, Panda, B P, Khanam, R, Najmi, A K, Akhtar, M

“…Myocardial infarction is an alarming health issue, needs great attention. The present study investigated the role of histamine-H3 receptor (H3R) agonist imetit…”
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Fabrication and evaluation of polymeric films for transdermal delivery of pinacidil by Aqil, M, Ali, A, Sultana, Y, Najmi, A K

“…The objective of the present work was to fabricate Eudragit RL 100-polyvinyl acetate films and evaluate their potential for transdermal drug delivery in a…”
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Transdermal drug delivery systems of a beta blocker: design, in vitro, and in vivo characterization by Aqil, M, Sultana, Yasmin, Ali, Asgar, Dubey, Kiran, Najmi, A K, Pillai, K K

“…The matrix type transdermal drug delivery systems (TDDS) of metoprolol were prepared by film casting technique using a fabricated stainless steel film casting…”
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Modulation of conditioned avoidance response and quetiapine-induced metabolic syndrome by rosuvastatin and CDP-choline in rats by Shafique, Ahmad, Pillai, K K, Hasan, Abdi Sayed Aliul, Najmi, A K

“…Sir, Metabolic syndrome diabetes mellitus, lipid abnormalities, and weight gain have increasingly been recognized with the use of the newer, atypical…”
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Silymarin, a flavonoid antioxidant, protects streptozotocin-induced lipid peroxidation and β-Cell damage in rat pancreas by Sharma, Manju, Anwer, Tarique, Pillai, K K, Haque, Syed Ehtaishamul, Najmi, A K, Sultana, Yasmin

“…The present study is aimed at finding the influence of silymarin (a flavonoid) (25 mg/kg & 50 mg/kg) in streptozotocin (STZ)-induced diabetic rats. Type 2…”
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Bisphosphonates: Future perspective for neurological disorders by Zameer, Saima, Najmi, Abul Kalam, Vohora, Divya, Akhtar, Mohd

“…Neurodegenerative disorders and osteoporosis share some common underlying pathological features including calcium overload, accumulation of toxic chemicals,…”
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Are us Private Payers' Medical Policies Influenced by Cochrane Evidence? by Singh, A, Hussain, S, Najmi, AK

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