Search Results - "Najmanová, Iveta"

The pharmacokinetics of flavanones by Najmanová, Iveta, Vopršalová, Marie, Saso, Luciano, Mladěnka, Přemysl

“…The intake of flavanones, the predominant flavonoid in the Citrus genus in human diets is variable but considerable. It is thus unsurprising that they have…”
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A Mixture of Phenolic Metabolites of Quercetin Can Decrease Elevated Blood Pressure of Spontaneously Hypertensive Rats Even in Low Doses by Najmanová, Iveta, Pourová, Jana, Mladěnka, Přemysl

“…Quercetin is proven to decrease arterial blood pressure when given orally. Its bioavailability is, however, low and, therefore, its metabolites could rather be…”
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Membrane and soluble endoglin role in cardiovascular and metabolic disorders related to metabolic syndrome by Vicen, Matej, Igreja Sá, Ivone Cristina, Tripská, Katarína, Vitverová, Barbora, Najmanová, Iveta, Eissazadeh, Samira, Micuda, Stanislav, Nachtigal, Petr

“…Membrane endoglin (Eng, CD105) is a transmembrane glycoprotein essential for the proper function of vascular endothelium. It might be cleaved by matrix…”
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Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats by Najmanová, Iveta, Pourová, Jana, Vopršalová, Marie, Pilařová, Veronika, Semecký, Vladimír, Nováková, Lucie, Mladěnka, Přemysl

“…Scope A number of studies have suggested that higher flavonoid intake is associated with lower cardiovascular mortality. The direct vasodilatory potential of…”
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Regulation and role of endoglin in cholesterol‐induced endothelial and vascular dysfunction in vivo and in vitro by Vicen, Matej, Vitverova, Barbora, Havelek, Radim, Blazickova, Katerina, Machacek, Miloslav, Rathouska, Jana, Najmanová, Iveta, Dolezelova, Eva, Prasnicka, Alena, Sternak, Magdalena, Bernabeu, Carmelo, Nachtigal, Petr

“…ABSTRACTOur objective was to investigate the effect of cholesterol [hypercholesterolemia and 7‐ketocholesterol (7K)] on endoglin (Eng) expression and…”
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Simultaneous determination of quercetin and its metabolites in rat plasma by using ultra-high performance liquid chromatography tandem mass spectrometry by Pilařová, Veronika, Plachká, Kateřina, Chrenková, Lucia, Najmanová, Iveta, Mladěnka, Přemysl, Švec, František, Novák, Ondřej, Nováková, Lucie

“…Fast, selective, and sensitive ultra-high performance liquid chromatography method with tandem mass spectrometry detection for the determination of quercetin…”
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Two flavonoid metabolites, 3,4-dihydroxyphenylacetic acid and 4-methylcatechol, relax arteries ex vivo and decrease blood pressure in vivo by Pourová, Jana, Najmanová, Iveta, Vopršalová, Marie, Migkos, Thomas, Pilařová, Veronika, Applová, Lenka, Nováková, Lucie, Mladěnka, Přemysl

“…The flavonoid quercetin reduces arterial blood pressure in animals and humans but the mechanisms remains elusive. The aim of this study was to test the…”
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Aqueous injection of quercetin: An approach for confirmation of its direct in vivo cardiovascular effects by Porcu, Elena Piera, Cossu, Massimo, Rassu, Giovanna, Giunchedi, Paolo, Cerri, Guido, Pourová, Jana, Najmanová, Iveta, Migkos, Thomas, Pilařová, Veronika, Nováková, Lucie, Mladěnka, Přemysl, Gavini, Elisabetta

“…[Display omitted] Potential positive effects of flavonol quercetin on humans were suggested by many studies. However, it is not clear if these effects are…”
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Cardiovascular effects of coumarins besides their antioxidant activity by Najmanová, Iveta, Doseděl, Martin, Hrdina, Radomír, Anzenbacher, Pavel, Filipský, Tomáš, Říha, Michal, Mladěnka, Přemysl

“…Coumarins are a large group of substances, primarily of plant origin. Like their more intensively examined congeners flavonoids, many of them are antioxidants…”
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Long term effects of soluble endoglin and mild hypercholesterolemia in mice hearts by Vitverova, Barbora, Najmanova, Iveta, Vicen, Matej, Tripska, Katarina, Sa, Ivone Cristina Igreja, Hyspler, Radek, Pericacho, Miguel, Nachtigal, Petr

“…Soluble endoglin (sEng) released into the circulation was suggested to be related to cardiovascular based pathologies. It was demonstrated that a combination…”
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Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver by Igreja Sá, Ivone Cristina, Tripska, Katarina, Hroch, Milos, Hyspler, Radomir, Ticha, Alena, Lastuvkova, Hana, Schreiberova, Jolana, Dolezelova, Eva, Eissazadeh, Samira, Vitverova, Barbora, Najmanova, Iveta, Vasinova, Martina, Pericacho, Miguel, Micuda, Stanislav, Nachtigal, Petr

“…Nonalcoholic steatohepatitis (NASH) is characterized by hepatic steatosis with inflammation and fibrosis. Membrane endoglin (Eng) expression is shown to…”
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Vasodilatory activity of human quercitin metabolites by Najmanová, Iveta, Vopršálová, Marie, Mladenka, Premysl

“…A large number of studies confirmed antihypertensive effect of quercetin. However, due to its low bioavailability, the mechanism of action has been remaining…”
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Food and Nutrition Poster Prize Winner P66 - Vasodilatory activity of human quercitin metabolites by Najmanová, Iveta, Vopršálová, Marie, Mladenka, Premysl

“…A large number of studies confirmed antihypertensive effect of quercetin. However, due to its low bioavailability, the mechanism of action has been remaining…”
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Preventive Beneficial Effect of an Aqueous Extract of Phyllanthus amarus Schum. and Thonn. (Euphorbiaceae) on DOCA-Salt–Induced Hypertension, Cardiac Hypertrophy and Dysfunction, and Endothelial Dysfunction in Rats by Yao, N'guessan Alain, Niazi, Zahid Rasul, Najmanová, Iveta, Kamagaté, Mamadou, Said, Amissi, Chabert, Philippe, Auger, Cyril, Die-Kakou, Henri, Schini-Kerth, Valérie

“…This study investigated the preventive effect of an aqueous extract of the whole plant of Phyllanthus amarus (AEPA) on blood pressure, cardiac, and endothelial…”
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O10 Beneficial effect of Phyllanthus amarus (Euphorbiaceae) on DOCA-salt-induced left ventricle cardiac hypertrophy and endothelial dysfunction in rats by Yao, Alain N’guessan, Rasul, Zahid, Najmanová, Iveta, Kamagaté, Mamadou, Said, Amissi, Chabert, Philippe, Auger, Cyril, Die-Kakou, Henri, Schini-Kerth, Valérie

“…Phyllanthus amarus is used in African traditional medicine to treat cardiovascular disorders such as hypertension. This study has evaluated the effect of an…”
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O31 Can colonic metabolites be responsible for the hypotensive effect of orally given quercetin? by Mladenka, Premysl, Najmanova, Iveta, Pourova, Jana, Migkos, Thomas, Vopršalová, Marie

“…Epidemiologic data suggest protective effects of higher flavonoid intake on cardiovascular diseases. Some human and animal studies reported a decrease in…”
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Soluble endoglin and hypercholesterolemia aggravate endothelial and vessel wall dysfunction in mouse aorta by Vitverova, Barbora, Blazickova, Katerina, Najmanova, Iveta, Vicen, Matej, Hyšpler, Radek, Dolezelova, Eva, Nemeckova, Ivana, Tebbens, Jurjen Duintjer, Bernabeu, Carmelo, Pericacho, Miguel, Nachtigal, Petr

“…Increased plasma levels of soluble endoglin (sEng) were detected in patients with endothelial dysfunction-related disorders and hypercholesterolemia. In this…”
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Soluble endoglin participate on the development of endothelial dysfunction: Or not? by Nachtigal, Petr, Blazickova, Katerina, Rathouska, Jana, Najmanova, Iveta, Vitverova, Barbora, Vicen, Matej, Dolezelova, Eva, Nemeckova, Ivana, Chlopicki, Stefan

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Soluble Endoglin Combined with Hypercholesterolemia Affects Vascular and Endothelial Function in Mice by Nachtigal, Petr, Vitverova, Barbora, Vicen, Matej, Najmanova, Iveta, Dolezelova, Eva, Bernabeu, Carmelo, Pericacho, Miguel

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