Search Results - "Najm, Saima"

Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis by Saima, Anjum, Irfan, Mobashar, Aisha, Jahan, Shah, Najm, Saima, Nafidi, Hiba-Allah, Bin Jardan, Yousef A, Bourhia, Mohammed

“…Apigenin is a phytochemical obtained from Its role in interstitial cystitis is not yet known. The present study is aimed at understanding the uroprotective and…”
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Schiff-Based Metal Complexes of Lamotrigine: Design, Synthesis, Characterization, and Biological Evaluation by Najm, Saima, Naureen, Humaira, Sultana, Kishwar, Anwar, Fareeha, Khan, Muhammad Mubbashir, Nadeem, Humaira, Saeed, Muhammad

“…In the current study, a series of Schiff base derivatives of lamotrigine are complexed with zinc, copper, silver, and tin and characterized by spectroscopic…”
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In-vivo anti-epileptic study of newly synthesized pregabalin derivatives based on docking studies by Asbat, Ayesha, Saleem, Farooq, Najm, Saima, Iqbal, Javed, Syed, Muhammad Ali, Azeem, Muhammad, Asbat, Syeda Javeria, Shoukat, Sadia

“…OBJECTIVEThe goal of the present study is to examine pretreatment with Schiff bases and derivatives of pregabalin along with their metal (Zn and Cu) complexes…”
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Synthesis, characterization, computational, anticancer and anti-inflammatory studies of pregabalin esters and their complexes with heavy metals by Asbat, Ayesha, Saleem, Farooq, Najm, Saima, Iqbal, Javed, Syed, Muhammad Ali, Ahmad, Sarfraz, Hanif, Sana, Azeem, Muhammad

“…•Novel series of ester derivatives and metal complexes of Pregabalin were designed andsynthesized.•Molecular docking studies were performed based on docking…”
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The anti-cancer potential of 2,4,6 tris-methyphenylamino1,3,5-triazine compound against mammary glands cancer: Via down-regulating the hormonal, inflammatory mediators, and oxidative stress by Mehmood, Yumna, Anwar, Fareeha, Saleem, Uzma, Hira, Sundas, Ahmad, Bashir, Bashir, Manal, Imtiaz, Muhammad Tayyab, Najm, Saima, Ismail, Tariq

“…Breast cancer is caused by abnormal growth of the cells and progressed due to the over-expression of estrogen (ER) and progesterone (PR). The current study was…”
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Metal complexes of pregabalin: Design, synthesis, characterization and biological evaluation by Asbat, Ayesha, Najm, Saima, Khan, Muhammad Mubbashir, Iqbal, Javed, Syed, Muhammad Ali, Khurshid, Sameera, Saleem, Farooq, Hanif, Sana

“…•Novel series of schiff base derivatives of pregabalin were designed and synthesized.•Molecular docking studies were performed; on the basis of docking score…”
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In-silico computational analysis of [6-(2, 3-Dichlorophenyl)-1, 2, 4-Triazine-3, 5-Diamine] metal complexes on voltage gated sodium channel and dihydrofolate reductase enzyme by Najm, Saima, Naureen, Humaira, Sultana, Kishwar, Anwar, Fareeha, Rehman, Sarah, Arshad, Shumaila, Khan, Muhammad Mubbashir

“…Epilepsy is the disease associated with seizures and convulsions. Various antiepileptic drugs have been used widely to treat these disorders. Lamotrigine…”
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Uroprotective Potential of Campesterol in Cyclophosphamide Induced Interstitial Cystitis; Molecular Docking Studies by Javed, Joham, Anjum, Irfan, Najm, Saima, Ali, Naila, Nasir Hayat Malik, Muhammad, Jahan, Shah, Dawoud, Turki M., Nafidi, Hiba‐Allah, Bourhia, Mohammed

“…Cyclophosphamide (CYP) is commonly used to treat cancer of the ovaries, breast, lymph, and blood system and produces interstitial cystitis (IC) via its…”
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Caftaric Acid Ameliorates Oxidative Stress, Inflammation, and Bladder Overactivity in Rats Having Interstitial Cystitis: An In Silico Study by Saima, Anjum, Irfan, Najm, Saima, Barkat, Kashif, Nafidi, Hiba-Allah, Bin Jardan, Yousef A., Bourhia, Mohammed

“…Interstitial cystitis (IC) is the principal unwanted effect associated with the use of cyclophosphamide (CYP). It results in increased oxidative stress,…”
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Evaluation of Sulfonamide Derivatives of Dagenan Chloride as Lipoxygenase and α-Glucosidase Inhibitors by Abbasi, Muhammad A, Najm, Saima, Rehman, Aziz-ur, Rasool, Shahid, Khan, Khalid M, Ashraf, Muhammad, Nasar, Rumana, Alam, Umber

“…Purpose: To study the enzyme inhibition activity of various sulfonamides derived from dagenan chloride. Methods: The synthesis of…”
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