Search Results - "Najjar, S M"

Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2 by Patel, P. R., Ramakrishnan, S. K., Kaw, M. K., Raphael, C. K., Ghosh, S., Marino, J. S., Heinrich, G., Lee, S. J., Bourey, R. E., Hill, J. W., Jung, D. Y., Morgan, D. A., Kim, J. K., Rahmouni, S. K., Najjar, S. M.

“…Aims/hypothesis The carcino-embryonic antigen-related cell adhesion molecule (CEACAM)2 is produced in many feeding control centres in the brain, but not in…”
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Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity by Haram, Per Magnus, Kemi, Ole J., Lee, Sang Jun, Bendheim, Marianne Ø., Al-Share, Qusay Y., Waldum, Helge L., Gilligan, Lori J., Koch, Lauren G., Britton, Steven L., Najjar, Sonia M., Wisløff, Ulrik

“…Aims The recent development of a rat model that closely resembles the metabolic syndrome allows to study the mechanisms of amelioration of the syndrome by…”
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Redefined Nomenclature for Members of the Carcinoembryonic Antigen Family by Beauchemin, N, Draber, P, Dveksler, G, Gold, P, Gray-Owen, S, Grunert, F, Hammarström, S, Holmes, K V, Karlsson, A, Kuroki, M, Lin, S H, Lucka, L, Najjar, S M, Neumaier, M, Obrink, B, Shively, J E, Skubitz, K M, Stanners, C P, Thomas, P, Thompson, J A, Virji, M, von Kleist, S, Wagener, C, Watt, S, Zimmermann, W

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Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1 by Huang, S, Kaw, M, Harris, M.T, Ebraheim, N, McInerney, M.F, Najjar, S.M, Lecka-Czernik, B

“…Abstract Type 2 diabetes is associated with normal-to-higher bone mineral density (BMD) and increased rate of fracture. Hyperinsulinemia and hyperglycemia may…”
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Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT by PALIOGIANNI, F, RAPTIS, A, AHUJA, S. S, NAJJAR, S. M, BOUMPAS, D. T

“…IL-2 gene transcription is affected by several nuclear proteins. We asked whether dexamethasone (Dex) and cyclosporin A (CsA) inhibit IL-2 gene transcription…”
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Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genes by Han, E, Phan, D, Lo, P, Poy, M N, Behringer, R, Najjar, S M, Lin, S H

“…The intercellular adhesion molecule CEACAM1, also known as C-CAM1 (where CAM is cell-adhesion molecule), can function as a tumour suppressor in several…”
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pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms by NAJJAR, S. M, ACCILI, D, PHILIPPE, N, JERNBERG, J, MARGOLIS, R, TAYLOR, S. I

“…The insulin receptor possesses tyrosine kinase activity which is thought to mediate the biological effects of insulin upon target cells. pp120 is a…”
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CEACAM1 regulates insulin clearance in liver by Najjar, Sonia M, Poy, Matthew N, Yang, Yan, Rezaei, Khadijeh, Fernström, Mats A, Lee, Abraham D, Kido, Yoshiaki, Erickson, Sandra K

“…We hypothesized that insulin stimulates phosphorylation of CEACAM1 which in turn leads to upregulation of receptor-mediated insulin endocytosis and degradation…”
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Erratum to: Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2 by Patel, P. R., Ramakrishnan, S. K., Kaw, M. K., Raphael, C. K., Ghosh, S., Marino, J. S., Heinrich, G., Lee, S. J., Bourey, R. E., Hill, J. W., Jung, D. Y., Morgan, D. A., Kim, J. K., Rahmouni, K., Najjar, S. M.

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Identification of Sp2 as a transcriptional repressor of carcinoembryonic antigen-related cell adhesion molecule 1 in tumorigenesis by PHAN, Dillon, CHENG, Chien-Jui, GALFIONE, Matthew, VAKAR-LOPEZ, Funda, TUNSTEAD, James, THOMPSON, Nancy E, BURGESS, Richard R, NAJJAR, Sonia M, YU-LEE, Li-Yuan, LIN, Sue-Hwa

“…Down-regulation of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) tumor suppressor gene expression is common in several malignancies…”
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Modifications of RNA Processing Modulate the Expression of Hemoglobin Genes by Kollia, Panagoula, Fibach, Eitan, Najjar, Sonia M., Schechter, Alan N., Noguchi, Constance Tom

“…The developmental changes in hemoglobin gene expression known as ``switching'' involve both the sequential activation and silencing of the individual globin…”
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Frequency of tracheobronchial foreign bodies in children and adolescents by Siddiqui, M A, Banjar, A H, Al-Najjar, S M, Al-Fattani, M M, Aly, M F

“…The problem of foreign body aspiration in the community has been studied and compared with other reports. We have retrospectively studied patients who had…”
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12411 Trends In Metabolic Dysfunction-associated Steatotic Liver Disease(MASLD) By Race/ethnicity: Data From NHANES 1988 To 2018 by Shaheen, M, Schrode, K, Pan, D, Najjar, S M, Friedman, T C

“…Disclosure: M. Shaheen: None. K. Schrode: None. D. Pan: None. S.M. Najjar: None. T.C. Friedman: None. Societies of the liver recommended replacing the term…”
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Molecular cloning of pp120/ECTO-ATPase, an endogenous substrate of the insulin receptor kinase by Najjar, S M, Philippe, N, Taylor, S I, Accili, D

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Sucrase-alpha-dextrinase in diabetic BioBreed rats: reversible alteration of subunit structure by Najjar, S M, Hampp, L T, Rabkin, R, Gray, G M

“…BioBreed (BB) Wistar rats develop diabetes mellitus, which closely resembles the human disease, in 50% of progeny. Intestinal sucrase-alpha-dextrinase, a…”
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pp120, a Substrate of the Insulin Receptor Tyrosine Kinase, Is Associated with Phosphatase Activity by Najjar, Sonia M.

“…pp120, a plasma membrane glycoprotein, is phosphorylated on Tyr488by the insulin receptor tyrosine kinase. This requires basal phosphorylation on Ser503by…”
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The Differential Effects of pp120 (Ceacam 1) on the Mitogenic Action of Insulin and Insulin-Like Growth Factor 1 Are Regulated by the Nonconserved Tyrosine 1316 in the Insulin Receptor by Soni, Payal, Lakkis, Montaha, Poy, Matthew N., Fernström, Mats A., Najjar, Sonia M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Insulin-Stimulated Phosphorylation of Recombinant pp120/HA4, an Endogenous Substrate of the Insulin Receptor Tyrosine Kinase by Najjar, Sonia M, Philippe, Neuberet, Suzuki, Yoshifumi, Ignacio, Gladys A, Formisano, Pietro, Accili, Domenico, Taylor, Simeon I

“…Insulin binding to the alpha-subunit of its receptor stimulates the receptor tyrosine kinase to phosphorylate the beta-subunit and several endogenous protein…”
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Altered intestinal and renal brush border amino-oligopeptidase structure in diabetes and metabolic acidosis: normal and biobreed (BB) rats by Najjar, S M, Hampp, L T, Rabkin, R, Gray, G M

“…Amino-oligopeptidase (AOP, aminopeptidase N), a major glycoprotein hydrolase in intestinal and kidney brush border membranes, plays a crucial role in digesting…”
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Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase by Formisano, P, Najjar, S M, Gross, C N, Philippe, N, Oriente, F, Kern-Buell, C L, Accili, D, Gorden, P

“…pp120/HA4 is a hepatocyte membrane glycoprotein phosphorylated by the insulin receptor tyrosine kinase. In this study, we have investigated the role of…”
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