Search Results - "Najib, Dally"
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Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
Published in Nature medicine (01-03-2021)“…Multiple myeloma (MM) is a neoplastic plasma-cell disorder characterized by clonal proliferation of malignant plasma cells. Despite extensive research, disease…”
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Safety and efficacy of the BNT162b mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-03-2022)“…Patients with chronic lymphocytic leukemia (CLL) have a suboptimal humoral response to vaccination. Recently, BNT162b2, an mRNA COVID-19 vaccine with a high…”
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The role of blood inflammatory markers in the preoperative diagnosis of acute appendicitis
Published in International journal of laboratory hematology (01-02-2024)“…Introduction Acute appendicitis (AA) requires a prompt diagnosis. According to postoperative pathological results, a significant number of appendectomies are…”
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Willingness and concerns of transfusion-dependent hematological patients toward the option of home transfusion therapy
Published in Palliative medicine (01-05-2021)“…Background: One of the main obstacles of providing home-based palliative care to transfusion-dependent hematology patients is the lack of home transfusions…”
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Efficacy and safety of Apixaban in the treatment of cerebral venous sinus thrombosis: a multi-center study
Published in Frontiers in neurology (16-05-2024)“…Information regarding the safety and efficacy of specific direct oral anticoagulants (DOAC) in the treatment of cerebral sinus and venous thrombosis (CSVT) is…”
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A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity
Published in PloS one (02-01-2019)“…Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The therapeutic approach to CLL includes chemotherapeutic regimens…”
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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K
Published in Annals of hematology (01-08-2021)“…Resistance remains the major clinical challenge for the therapy of Philadelphia chromosome–positive (Ph+) leukemia. With the exception of ponatinib, all…”
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Polatuzumab-based regimen or CAR T cell for patients with refractory/relapsed DLBCL—a matched cohort analysis
Published in Annals of hematology (01-04-2022)“…Polatuzumab (Pola)-based regimens and chimeric antigen receptor T (CAR T) cells provide superior outcome compared to conventional chemoimmunotherapy in…”
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A new risk model to predict time to first treatment in chronic lymphocytic leukemia based on heavy chain immunoparesis and summated free light chain
Published in European journal of haematology (01-10-2019)“…Background Chronic lymphocytic leukemia (CLL) is frequently accompanied by immune dysregulation. Aims In this multicenter prospective study, we investigated…”
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Clinical Significance and Outcome in Patients with Asymptomatic Versus Symptomatic Subsegmental Pulmonary Embolism
Published in Journal of clinical medicine (18-02-2023)“…The clinical significance and optimal therapy of patients with subsegmental pulmonary embolism (SSPE) remain controversial. We used the data in the RIETE…”
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Differentiating ischemic from non-ischemic chest pain using white blood cell-surface inflammatory and coagulation markers
Published in Journal of thrombosis and thrombolysis (01-08-2012)“…Chest pain is one of the most common complaints seen in emergency departments (ED), up to 5–8 % of all ED visits. About 50–60 % of chest pain patients…”
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Predictive factors of bleeding and thrombosis during induction therapy in acute promyelocytic leukemia—a single center experience in 34 patients
Published in Thrombosis research (2005)“…In this retrospective study, the hemorrhagic and thrombotic events are reported at presentation and during induction in 34 consecutive acute promyelocytic…”
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Efficacy of a third BNT162b2 mRNA COVID-19 vaccine dose in patients with CLL who failed standard 2-dose vaccination
Published in Blood (03-02-2022)“…Patients with chronic lymphocytic leukemia (CLL) have an impaired antibody response to coronavirus disease 2019 (COVID-19) vaccination. Here, we evaluated the…”
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The Impact of BMI on the Outcome of Lymphoma Treatment
Published in Blood (15-11-2022)Get full text
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Insights into direct anticoagulants
Published in Blood coagulation & fibrinolysis (01-07-2015)“…For the past five decades, vitamin K antagonists (VKA) have been the only class of oral anticoagulants available for treating or preventing venous and arterial…”
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A New Take on a Resource-Based Model of Quality of Life in Hemato-Oncological Patients: Demographic, Personal, and Social Factors
Published in Journal of clinical psychology in medical settings (01-12-2019)“…This study tests a new comprehensive model accounting for the role of demographic, personal, and social factors in quality of life (QOL) among a sample of…”
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Can Blood Inflammatory Markers Identify Pregnant Women with Preeclampsia? Still a Controversial Issue
Published in The Israel Medical Association journal (01-09-2024)“…Preeclampsia is a unique vascular disease during pregnancy that generally appears after 20 of weeks gestation or until 6 weeks after delivery. Left…”
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Ethnic disparities in presentation but not outcome in multiple myeloma patients: a multicenter retrospective study in Northern Israel
Published in Leukemia & lymphoma (01-12-2023)“…Several studies showed ethnic disparities in multiple myeloma (MM) incidence and prognosis. In order to compare prognosis and overall survival between…”
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Can an Anemic Patient Be a Partner to Treatment Decision-Making?
Published in The Israel Medical Association journal (01-11-2023)Get full text
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