Search Results - "Najar, Mehdi"

The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings by Merimi, Makram, El-Majzoub, Rania, Lagneaux, Laurence, Moussa Agha, Douâa, Bouhtit, Fatima, Meuleman, Nathalie, Fahmi, Hassan, Lewalle, Philippe, Fayyad-Kazan, Mohammad, Najar, Mehdi

“…Graphical Abstract The road map of MSC review. In recent decades, research on the therapeutic potential of progenitor cells has advanced considerably. Among…”
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The Medicinal Potential of Mesenchymal Stem/Stromal Cells in Immuno- and Cancer Therapy by Najar, Mehdi, Fahmi, Hassan, Merimi, Makram

“…Cancer is a highly lethal disease that causes millions of deaths worldwide, thus representing a major public health challenge [...]…”
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New Anti-Leukemic Effect of Carvacrol and Thymol Combination through Synergistic Induction of Different Cell Death Pathways by Bouhtit, Fatima, Najar, Mehdi, Moussa Agha, Douâa, Melki, Rahma, Najimi, Mustapha, Sadki, Khalid, Boukhatem, Noureddine, Bron, Dominique, Meuleman, Nathalie, Hamal, Abdellah, Lagneaux, Laurence, Lewalle, Philippe, Merimi, Makram

“…Acute myeloid leukemia (AML) is a cancer of the myeloid lineage of blood cells, and treatment for AML is lengthy and can be very expensive. Medicinal plants…”
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Mesenchymal Stromal Cell-Based Therapy: New Perspectives and Challenges by Najar, Mehdi, Bouhtit, Fatima, Melki, Rahma, Afif, Hassan, Hamal, Abdellah, Fahmi, Hassan, Merimi, Makram, Lagneaux, Laurence

“…Stem cells have been the focus of intense research opening up new possibilities for the treatment of various diseases. Mesenchymal stromal cells (MSCs) are…”
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Mitochondrial remodeling in hepatic differentiation and dedifferentiation by Wanet, Anaïs, Remacle, Noémie, Najar, Mehdi, Sokal, Etienne, Arnould, Thierry, Najimi, Mustapha, Renard, Patricia

“…Mitochondrial biogenesis and metabolism have recently emerged as important actors of stemness and differentiation. On the one hand, the differentiation of stem…”
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Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia by Fayyad-Kazan, Hussein, Bitar, Nizar, Najar, Mehdi, Lewalle, Philippe, Fayyad-Kazan, Mohammad, Badran, Rabih, Hamade, Eva, Daher, Ahmad, Hussein, Nader, ElDirani, Rim, Berri, Fadwa, Vanhamme, Luc, Burny, Arsène, Martiat, Philippe, Rouas, Redouane, Badran, Bassam

“…MicroRNAs (miRNAs) are small (19-22-nt) single-stranded noncoding RNA molecules whose deregulation of expression can contribute to human disease including the…”
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Mesenchymal Stromal Cells and Toll-Like Receptor Priming: A Critical Review by Najar, Mehdi, Krayem, Mohammad, Meuleman, Nathalie, Bron, Dominique, Lagneaux, Laurence

“…Mesenchymal Stromal Cells (MSCs) are potential cellular candidates for several immunotherapy purposes. Their multilineage potential and immunomodulatory…”
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Therapeutic Mesenchymal Stem/Stromal Cells: Value, Challenges and Optimization by Najar, Mehdi, Melki, Rahma, Khalife, Ferial, Lagneaux, Laurence, Bouhtit, Fatima, Moussa Agha, Douaa, Fahmi, Hassan, Lewalle, Philippe, Fayyad-Kazan, Mohammad, Merimi, Makram

“…Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular environments suitable for tissue repair and regeneration. Among…”
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Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton’s Jelly and bone marrow sources by Najar, Mehdi, Raicevic, Gordana, Boufker, Hicham Id, Kazan, Hussein Fayyad, Bruyn, Cécile De, Meuleman, Nathalie, Bron, Dominique, Toungouz, Michel, Lagneaux, Laurence

“…Due to their immunomodulatory properties, adipose tissue (AT) and Wharton’s Jelly (WJ) constitute valuable alternatives to BM as sources of MSCs for managing…”
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Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging by Merimi, Makram, Buyl, Karolien, Daassi, Dhouha, Rodrigues, Robim M., Melki, Rahma, Lewalle, Philippe, Vanhaecke, Tamara, Fahmi, Hassan, Rogiers, Vera, Lagneaux, Laurence, De Kock, Joery, Najar, Mehdi

“…Adult human subcutaneous adipose tissue (AT) harbors a rich population of mesenchymal stromal cells (MSCs) that are of interest for tissue repair. For this…”
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Immune regulation and therapeutic application of T regulatory cells in liver diseases by Ajith, Ananya, Merimi, Makram, Arki, Mandana Kazem, Hossein-Khannazer, Nikoo, Najar, Mehdi, Vosough, Massoud, Sokal, Etienne Marc, Najimi, Mustapha

“…CD4 CD25 FOXP3 T regulatory cells (Tregs) are a subset of the immunomodulatory cell population that can inhibit both innate and adaptive immunity by various…”
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Identification of Acute Myeloid Leukemia Bone Marrow Circulating MicroRNAs by Moussa Agha, Douâa, Rouas, Redouane, Najar, Mehdi, Bouhtit, Fatima, Naamane, Najib, Fayyad-Kazan, Hussein, Bron, Dominique, Meuleman, Nathalie, Lewalle, Philippe, Merimi, Makram

“…In addition to their roles in different biological processes, microRNAs in the tumor microenvironment appear to be potential diagnostic and prognostic…”
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Inflammation modifies the pattern and the function of Toll-like receptors expressed by human mesenchymal stromal cells by Raicevic, Gordana, Rouas, Redouane, Najar, Mehdi, Stordeur, Patrick, Id Boufker, Hicham, Bron, Dominique, Martiat, Philippe, Goldman, Michel, Nevessignsky, Michel T, Lagneaux, Laurence

“…Abstract Mesenchymal stromal cells (MSC) are involved in tissue repair and in the regulation of immune responses. MSC express Toll-like receptors (TLR) known…”
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Mesenchymal Stromal Cell Immunology for Efficient and Safe Treatment of Osteoarthritis by Najar, Mehdi, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Fahmi, Hassan

“…Mesenchymal stem cell (MSC) therapy represents a promising approach for the treatment of osteoarthritis (OA). MSCs can be readily isolated from multiple…”
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Immuno-comparative screening of adult-derived human liver stem/progenitor cells for immune-inflammatory-associated molecules by Merimi, Makram, Lagneaux, Laurence, Lombard, Catherine A., Agha, Douâa Moussa, Bron, Dominique, Lewalle, Philippe, Meuleman, Nathalie, Najimi, Mustapha, Sokal, Etienne M., Najar, Mehdi

“…Objective One of the main challenges in liver cell therapy is the replacement of damaged cells and the induction of a tolerogenic microenvironment to promote…”
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The immunogenic profile and immunomodulatory function of mesenchymal stromal / stem cells in the presence of Ptychotis verticillata by Najar, Mehdi, Bouhtit, Fatima, Rahmani, Saida, Bouali, Abderrahim, Melki, Rahma, Najimi, Mustapha, Lewalle, Philippe, Merimi, Makram

“…Mesenchymal stromal/stem cells (MSCs) are considered to be a promising immunotherapeutic tool due to their easy accessibility, culture expansion possibilities,…”
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Comparison and immunobiological characterization of retinoic acid inducible gene-I-like receptor expression in mesenchymal stromal cells by Raicevic, Gordana, Najar, Mehdi, Busser, Hélène, Crompot, Emerence, Bron, Dominique, Toungouz, Michel, Lagneaux, Laurence

“…Due to their immunomodulatory and regenerative properties, Mesenchymal stromal cells (MSC) have generated major interests in several clinical settings…”
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The Immunological Profile of Adipose Mesenchymal Stromal/Stem Cells after Cell Expansion and Inflammatory Priming by Buyl, Karolien, Merimi, Makram, Rodrigues, Robim M, Rahmani, Saida, Fayyad-Kazan, Mohammad, Bouhtit, Fatima, Boukhatem, Noureddine, Vanhaecke, Tamara, Fahmi, Hassan, De Kock, Joery, Najar, Mehdi

“…AT-MSCs display great immunoregulatory features, making them potential candidates for cell-based therapy. This study aimed to evaluate the "RBC lysis buffer"…”
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Mesenchymal Stem/Stromal Cells as a Therapeutic Tool in Cell-Based Therapy and Regenerative Medicine: An Introduction Expertise to the Topical Collection by Merimi, Makram, Fahmi, Hassan, De Kock, Joery, Beguin, Charline, Burny, Arsène, Moll, Guido, Poggi, Alessandro, Najar, Mehdi

“…We are pleased to present this opening editorial, introducing our topical collection, “The New Era of Mesenchymal Stromal/Stem Cell Functional Application:…”
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Umbilical Cord Mesenchymal Stromal/Stem Cells and Their Interplay with Th-17 Cell Response Pathway by Najar, Mehdi, Rahmani, Saida, Faour, Wissam H, Alsabri, Sami G, Lombard, Catherine A, Fayyad-Kazan, Hussein, Sokal, Etienne M, Merimi, Makram, Fahmi, Hassan

“…As a form of immunomodulatory therapeutics, mesenchymal stromal/stem cells (MSCs) from umbilical cord (UC) tissue were assessed for their dynamic interplay…”
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