Search Results - "Najar, Imtiyaz"
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On Particle Production Mechanism in High-Energy Nucleus–Nucleus Collisions
Published in Journal of the Physical Society of Japan (15-01-2023)“…We have investigated the systematic study of multiplicity correlations in terms of the dynamical fluctuation observable (σ2c) in the forward-backward…”
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Anti-oxidant and anti-inflammatory potential of different polymer-based mesalamine delayed-release granules in TNBS-induced ulcerative colitis in wistar rats
Published in Saudi pharmaceutical journal (01-01-2024)“…Ulcerative colitis (UC) is an inflammatory condition of colon characterized by severe damage to the innermost colon tissues. A number of studies described the…”
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Impact of empagliflozin add-on therapy on quality of life in patients of type 2 diabetes mellitus with hypertension: A prospective study
Published in Indian journal of public health (01-11-2022)“…Background: Diabetes has a negative impact on patient's quality of life (QoL). Comorbidities and polypharmacy further worsen their QoL. Thus, in addition to…”
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PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India
Published in Tumor biology (01-10-2017)“…Platelet-derived growth factor receptor has been implicated in many malignant and non-malignant diseases. Platelet-derived growth factor receptor-α is a…”
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Cardioprotection by Citrus grandis (L.) Peel Ethanolic Extract in Alloxan-Induced Cardiotoxicity in Diabetic Rats
Published in BioMed research international (16-06-2022)“…Diabetic cardiomyopathy (DCM) pathogenesis is multifarious, and there are insufficient therapeutic options to treat DCM. The present research explored the…”
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EDITORIAL SCOPE: GEOTECHNICAL EARTHQUAKE ENGINEERING EDITION
Published in Journal of Civil Engineering, Science and Technology (Online) (25-09-2023)“…One of the main civil engineering disciplines is currently the focus area of the Journal of Civil Engineering, Science, and Technology (JCEST): geotechnical…”
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MO10-5 JAK2/miR-21/PTEN axis – an important pathway in JAK2(V617F) positive myeloproliferative neoplasias
Published in Annals of oncology (01-07-2022)Get full text
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MO10-6 miR-4647 an early biomarker of outcome in chronic myeloid leukaemia patients
Published in Annals of oncology (01-07-2022)Get full text
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Abstract 831: Hypermethylation in promoter regions of CpG islands of multiple genes is associated with disease progression and molecular response in chronic myelogenous leukemia
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Chronic myelogenous leukemia (CML) has a typical progressive course with transition from a less aggressive chronic phase to a terminal more aggressive blast…”
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JAK2 (V617F) positively regulates PD-L1 mRNA expression via STAT3/5 activation in MNP (PV and ET) patients
Published in Annals of oncology (01-10-2019)Get full text
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MO3-1-1JAK2 (V617F) positively regulates PD-L1 mRNA expression via STAT3/5 activation in MNP (PV and ET) patients
Published in Annals of oncology (01-10-2019)“…Abstract Background Escalated PD-L1 expression is reported in many cancer types initiating an immune escape mechanism. This led to the development of…”
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Escalated activation ofSTAT3 due to JAK2 V617F activatingmutation causesdownregulation ofPTEN via miRNA 21overexpression
Published in Annals of oncology (01-10-2019)Get full text
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MO3-1-2Escalated activation ofSTAT3 due to JAK2 V617F activatingmutation causesdownregulation ofPTEN via miRNA 21overexpression
Published in Annals of oncology (01-10-2019)“…Abstract Background Mutations in Janus kinase 2 (JAK2) genes are the genetic characteristic of BCR-ABL1-negative myeloproliferative neoplasms (MPN). JAK2 V617F…”
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Investigation of the Sustainability Potentials in the Ten House Project Bangkok-Thailand
Published in International journal of sustainable development and planning (31-03-2023)Get full text
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Therapeutic efficacy of rifaximin loaded tamarind gum polysaccharide nanoparticles in TNBS induced IBD model Wistar rats
Published in Reports of practical oncology and radiotherapy (01-01-2021)“…Rifaximin is a non-systemic antibiotic used in the treatment of inflammatory bowel disease (IBD). Antibiotics are demonstrating a significant role in the…”
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Altered Expression of Pdgfrα and Its Downstream Signalling Components May be Causal in the Development of Imatinib Induced Thrombocytopenia in CML Patients Receiving Imatinib Treatment
Published in Blood (08-12-2017)“…Background: The main regulators of most of the cellular signalling pathways are protein kinases. Among these the receptor tyrosine kinases (RTKs) play…”
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PDGFRα polymorphisms influence risk of developing imatinib induced thrombocytopenia inchronic myeloid leukaemia patients
Published in Annals of oncology (01-10-2017)Get full text
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A deletion polymorphism in the RIZ gene is associated with increased progression of imatinib treated chronic myeloid leukemia patients
Published in Leukemia & lymphoma (03-07-2017)“…RIZ1 encodes a retinoblastoma (Rb)-interacting zinc finger protein, is commonly lost or expressed at reduced levels in cancer cells. The RIZ1 gene locus…”
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Prognostic and diagnostic significance of epigenetic alterations of p16 and DAPK1 promoter sequences in patients with epithelial ovarian carcinoma (EOC)
Published in Journal of clinical oncology (20-10-2012)“…Abstract only 62 Background: Novel strategies for early detection of EOC, the most common and second most lethal cancer in Indian women, are urgently needed…”
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