Search Results - "Nair, Vidhya R."

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis by Collins, Angela C., Cai, Haocheng, Li, Tuo, Franco, Luis H., Li, Xiao-Dong, Nair, Vidhya R., Scharn, Caitlyn R., Stamm, Chelsea E., Levine, Beth, Chen, Zhijian J., Shiloh, Michael U.

“…Activation of the DNA-dependent cytosolic surveillance pathway in response to Mycobacterium tuberculosis infection stimulates ubiquitin-dependent autophagy and…”
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The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense by Franco, Luis H., Nair, Vidhya R., Scharn, Caitlyn R., Xavier, Ramnik J., Torrealba, Jose R., Shiloh, Michael U., Levine, Beth

“…During antibacterial autophagy, ubiquitination of intracellular bacteria recruits proteins that mediate bacterial delivery to the lysosome for degradation…”
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Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection by Scharn, Caitlyn R, Collins, Angela C, Nair, Vidhya R, Stamm, Chelsea E, Marciano, Denise K, Graviss, Edward A, Shiloh, Michael U

“…Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for 1.5 million deaths annually. We previously showed that M. tuberculosis…”
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Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection by Nair, Vidhya R., Franco, Luis H., Zacharia, Vineetha M., Khan, Haaris S., Stamm, Chelsea E., You, Wu, Marciano, Denise K., Yagita, Hideo, Levine, Beth, Shiloh, Michael U.

“…The prevailing paradigm is that tuberculosis infection is initiated when patrolling alveolar macrophages and dendritic cells within the terminal alveolus…”
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Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis by Khan, Haaris S, Nair, Vidhya R, Ruhl, Cody R, Alvarez-Arguedas, Samuel, Galvan Rendiz, Jorge L, Franco, Luis H, Huang, Linzhang, Shaul, Philip W, Kim, Jiwoong, Xie, Yang, Mitchell, Ron B, Shiloh, Michael U

“…(Mtb) can enter the body through multiple routes, including via specialized transcytotic cells called microfold cells (M cell). However, the mechanistic basis…”
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A baculovirus-conjugated mimotope vaccine targeting Mycobacterium tuberculosis lipoarabinomannan by Shin, Hyun-Jin, Franco, Luis H, Nair, Vidhya R, Collins, Angela C, Shiloh, Michael U

“…Mycobacterium tuberculosis, the causative agent of tuberculosis, is a major cause of morbidity and mortality worldwide. However, an effective vaccine for M…”
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Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector by Stamm, Chelsea E, Pasko, Breanna L, Chaisavaneeyakorn, Sujittra, Franco, Luis H, Nair, Vidhya R, Weigele, Bethany A, Alto, Neal M, Shiloh, Michael U

“…(Mtb), the causative agent of tuberculosis, is one of the most successful human pathogens. One reason for its success is that Mtb can reside within host…”
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cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis by Zacharia, Vineetha M, Manzanillo, Paolo S, Nair, Vidhya R, Marciano, Denise K, Kinch, Lisa N, Grishin, Nick V, Cox, Jeffery S, Shiloh, Michael U

“…Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously…”
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Mouse Models to Study Natural Killer Cell-Mediated Immunosurveillance and Metastatic Latency by Nair, Vidhya R, Malladi, Srinivas

“…Metastatic latency is a major concern in the clinic, yet how these disseminated cancer cells survive and initiate metastases is unknown (Massagué and Obenauf,…”
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The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense by Franco, Luis H., Nair, Vidhya R., Scharn, Caitlyn R., Xavier, Ramnik J., Torrealba, Jose R., Shiloh, Michael U., Levine, Beth

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The ubiquitin-ligase Smurf1 functions in selective autophagy of M. tuberculosis and anti-tuberculous host defense by Franco, Luis H., Nair, Vidhya R., Scharn, Caitlyn R., Xavier, Ramnik J., Torrealba, Jose R., Shiloh, Michael U., Levine, Beth

“…During antibacterial autophagy, ubiquitination of intracellular bacteria recruits proteins that mediate bacterial delivery to the lysosome for degradation…”
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Heme oxygenase-1 regulates inflammation and mycobacterial survival in human macrophages during M. tuberculosis infection by Scharn, Caitlyn R., Collins, Angela C., Nair, Vidhya R., Stamm, Chelsea E., Marciano, Denise K., Graviss, Edward A., Shiloh, Michael U.

“…Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is responsible for 1.5 million deaths annually. We previously showed that Mtb infection…”
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Abstract B68: Pomegranate extract inhibits growth and viability of human pancreatic cancer cells in vitro by Nair, Vidhya R., Dai, Zhaoli, Khan, Maruf, Ciolino, Henry P.

“…Abstract Pancreatic cancer is highly resistant to chemotherapeutic agents, and therefore new therapeutic and chemopreventive agents are needed. In the present…”
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italic toggle="yes">cor /italic>, a Novel Carbon Monoxide Resistance Gene, Is Essential for Mycobacterium tuberculosis Pathogenesis by Vineetha M. Zacharia, Paolo S. Manzanillo, Vidhya R. Nair, Denise K. Marciano, Lisa N. Kinch, Nick V. Grishin, Jeffery S. Cox, Michael U. Shiloh

“…ABSTRACT Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously…”
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Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations by Abdel-Rahman, Wael M, Al-khayyal, Noura A, Nair, Vidhya A, Aravind, S R, Saber-Ayad, Maha

“…AIM To characterize AXL receptor tyrosine kinase(AXL)expression in relationship to tumor protein P53(TP53gene,p53 protein)and its role in tumor invasion and…”
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