Search Results - "Nair, Sukesh"

Sensitivity and Robustness of Spatially Dependent Thrombin Generation and Fibrin Clot Propagation by Kuprash, Anna D., Shibeko, Alexey M., Vijay, Ramya, Nair, Sukesh C., Srivastava, Alok, Ataullakhanov, Fazoil I., Panteleev, Mikhail A., Balandina, Anna N.

“…Blood coagulation is a delicately regulated space- and time-dependent process that leads to the formation of fibrin clots preventing blood loss upon vascular…”
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Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance by Chendamarai, Ezhilarasi, Ganesan, Saravanan, Alex, Ansu Abu, Kamath, Vandana, Nair, Sukesh C, Nellickal, Arun Jose, Janet, Nancy Beryl, Srivastava, Vivi, Lakshmi, Kavitha M, Viswabandya, Auro, Abraham, Aby, Aiyaz, Mohammed, Mullapudi, Nandita, Mugasimangalam, Raja, Padua, Rose Ann, Chomienne, Christine, Chandy, Mammen, Srivastava, Alok, George, Biju, Balasubramanian, Poonkuzhali, Mathews, Vikram

“…There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases…”
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Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia by Palani, Hamenth Kumar, Ganesan, Saravanan, Balasundaram, Nithya, Venkatraman, Arvind, Kulkarni, Uday, Korula, Anu, Nair, Sukesh C, Mani, Thenmozhi, Balasubramanian, Poonkuzhali, Abraham, Aby, Puttamallesh, Vinuth N, Gowda, Harsha, Mathews, Vikram

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A study to compare Hematopoietic Progenitor Cell count determined on a next‐generation automated cell counter with flow cytometric CD34 count in peripheral blood and the harvested peripheral blood stem cell graft from autologous and allogenic donors by Mishra, Shruti, Kulkarni, Uday, Mathews, Nitty, V, Ramya, Ch. Nair, Sukesh, George, Biju, Mammen, Joy J.

“…Introduction A successful bone marrow transplant requires a minimum of 2‐4 × 106 cells/kg patient body weight of CD 34+ cells to be transfused, where…”
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Management of relapse in acute promyelocytic leukaemia treated with up‐front arsenic trioxide‐based regimens by Fouzia, N. A., Sharma, Vibhor, Ganesan, Saravanan, Palani, Hamenth K., Balasundaram, Nithya, David, Sachin, Kulkarni, Uday P., Korula, Anu, Devasia, Anup J., Nair, Sukesh C., Janet, Nancy Beryl, Abraham, Aby, Mani, Thenmozhi, Lakshmanan, Jeyaseelan, Balasubramanian, Poonkuzhali, George, Biju, Mathews, Vikram

“…Summary The standard of care for patients with acute promyelocytic leukaemia (APL) relapsing after front‐line treatment with arsenic trioxide (ATO)‐based…”
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Reticuloendothelial activation correlates with disease severity and predicts mortality in severe alcoholic hepatitis by Vijayalekshmi, Balakrishnan, Sharma, Anand, Prabhu, Savit B, Nair, Sukesh C., Mammen, Joy, Goel, Ashish, Zachariah, Uday George, Dutta, Amit Kumar, Balasubramanian, Kunissery A, Elias, Elwyn, Eapen, Chundamannil E.

“…Overactivation of reticuloendothelial cells lining liver sinusoids - Kupffer cells (macrophages) and sinusoidal endothelial cells - may narrow the sinusoidal…”
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Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A by Dave, Rutvi G, Geevar, Tulasi, Mammen, Joy J, Vijayan, Ramya, Mahasampath, Gowri, Nair, Sukesh C

“…Hemophilia A is classified as mild, moderate, and severe based on Factor VIII levels (FVIII). Clot-based assays only detect initiation of thrombin generation,…”
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Comparing two techniques of performing an epidural catheter-assisted epidural blood patch using a 20 ml syringe versus a 5 ml syringe and its effect on clotting time, the strength of clot retraction and haemolysis - A prospective in vitro study (EC-EBP study) by Mariappan, Ramamani, Kumar, Snehil, Raju, Krishnaprabhu, Daniel, Dolly, Nair, Sukesh, Subramani, Sathya

“…Background and Aims: Epidural blood patch (EBP) is performed by injecting autologous blood into the epidural space using a Tuohy needle. Certain clinical…”
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Platelets provide robustness of spatial blood coagulation to the variation of initial conditions by Balandina, Anna N., Koltsova, Ekaterina M., Shibeko, Alexey M., Kuprash, Anna D., Budkova, Valentina A., Demina, Irina A., Ignatova, Anastasiya A., Fadeeva, Olga A., Vijay, Ramya, Nair, Sukesh C., Srivastava, Alok, Shi, Qiang, Ataullakhanov, Fazoil I., Panteleev, Mikhail A.

“…Activated platelets provide phospholipid surface and secrete coagulation factors, enhancing blood clotting. We investigated the role of platelets in the…”
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Diagnostic utility of flow cytometry based coated‐platelets assay as a biomarker to predict thrombotic or hemorrhagic phenotype in acute stroke by Dave, Rutvi Gautam, Geevar, Tulasi, Aaron, Sanjith, Benjamin, Rohit, Mammen, Joy, Kumar, Snehil, Vijayan, Ramya, Gowri, Mahasampath, Nair, Sukesh C

“…Background Coated‐platelets are sub‐population of platelets “coated” with highly procoagulant proteins and phosphatidylserine that sustains thrombin…”
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Atypical Morphological Presentation of Neoplastic Plasma Cells: A Series of Five Cases by Ganesamoorthy, Vinoth Kumar, Dave, Rutvi Gautam, Sigamani, Elanthenral, Devasia, Anup J, Nair, Sukesh C, Maddali, Madhavi, Chinniah, Praveen Kumar

“…The diagnosis of Multiple Myeloma (MM) is made by demonstration clonal plasma cells in Bone Marrow (BM) aspiration/biopsy, in addition to assessing serum…”
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Thromboelastograph:A prognostic marker in sepsis with organ dysfunction without overt bleeding by Ninan K, Fibi, Iyadurai, Ramya, Varghese, Justin K., Geevar, Tulasi, Nair, Sukesh C., Yadav, Bijesh, Carey, Ronald Albert Benton, Sadiq J, Mohammad, Koshy, Maria, Ralph, Ravikar, Peter, John Victor

“…Coagulation abnormalities are not infrequent in sepsis. It is unclear if abnormalities in thromboelastogram (TEG) are associated with mortality in patients…”
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Resource utilization and cost effectiveness of treating acute promyelocytic leukaemia using generic arsenic trioxide by Bankar, Aniket, Korula, Anu, Kulkarni, Uday P., Devasia, Anup J., NA, Fouzia, Lionel, Sharon, Abraham, Aby, Balasubramanian, Poonkuzhali, Janet, Nancy Beryl, Nair, Sukesh C., S, Sezlian, Jeyaseelan, Visali, N, Jeyaseelan, Prasad, Jasmine, George, Biju, Mathews, Vikram

“…Summary Arsenic trioxide (ATO)‐based regimens are the standard of care for treating acute promyelocytic leukaemia (APL) and have replaced chemotherapy‐based…”
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Focused panel sequencing points to genetic predisposition in non-cirrhotic intrahepatic portal hypertension patients in India by Aaron, Rekha, Premkumar, Kalpana, Chapla, Aaron, Vijayalekshmi, B., Zachariah, Uday, Elias, Elwyn, Kodiatte, Thomas Alex, Daniel, Dolly, Jude, John, Balasubramanian, K. A., Nair, Sukesh C., Thomas, Nihal, Ramakrishna, Banumathi, Eapen, C. E., Goel, Ashish

“…Objective Non-cirrhotic intrahepatic portal hypertension (NCIPH), a portal microangiopathy affecting small portal vein radicles, is a disease of Indian…”
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Centrifugal technique of plasma exchange and low-dose steroid to treat very severe alcoholic hepatitis patients: A retrospective analysis by Kumar, Santhosh E, Chellaiya, Gayathiri K, Singh, Kunwar A, Karuppusami, Reka, Daniel, Dolly, David, Vinoi G, Nair, Sukesh C, Varughese, Santosh, Mammen, Joy, Elias, Elwyn, Eapen, Chundammanil E, Zachariah, Uday G, Goel, Ashish

“…Low-volume plasma exchange (PLEX) and low-dose steroid improve survival in severe alcoholic hepatitis. We aimed to compare one-year survival of very severe…”
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Impact of Cell-of-Origin on Outcome of Patients With Diffuse Large B-Cell Lymphoma Treated With Uniform R-CHOP Protocol: A Single-Center Retrospective Analysis From North India by Gogia, Ajay, Nair, Sukesh, Arora, Shalabh, Kumar, Lalit, Sharma, Atul, Gupta, Ritu, Biswas, Ahitagni, Mallick, Saumyaranjan

“…There is a scarcity of data from India on the impact of cell of origin (COO) on outcomes of diffuse large B-cell lymphoma (DLBCL). This study was conducted to…”
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Determination of fibrin clot growth and spatial thrombin propagation in the presence of different types of phospholipid surfaces by Koltsova, Ekaterina M., Kuprash, Anna D., Dashkevich, Natalya M., Vardanyan, David M., Chernyakov, Artem V., Kumskova, Maria A., Nair, Sukesh C., Srivastava, Alok, Ataullakhanov, Fazoil I., Panteleev, Mikhail A., Balandina, Anna N.

“…In this work, we present a new method-Thrombodynamics-4D-for the assessment of both plasma and platelet contributions to clotting. Thrombodynamics-4D…”
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Low Volume Plasma Exchange and Low Dose Steroid Improve Survival in Patients With Alcohol-Related Acute on Chronic Liver Failure and Severe Alcoholic Hepatitis – Preliminary Experience by Kumar, Santhosh E., Goel, Ashish, Zachariah, Uday, Nair, Sukesh C., David, Vinoi G., Varughese, Santosh, Gandhi, Prashanth B., Barpha, Amit, Sharma, Anand, Vijayalekshmi, Balakrishnan, Balasubramanian, Kunissery A., Elias, Elwyn, Eapen, Chundamannil Eapen

“…Alcohol-related acute on chronic liver failure (A-ACLF) patients have high short-term mortality and are poor candidates for steroid therapy. Plasma exchange…”
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Cytomorphometric Neutrophil and Monocyte Markers May Strengthen the Diagnosis of Sepsis by Mammen, Joy, Choudhuri, Jui, Paul, Joshua, Sudarsan, Thomas Isaiah, Josephine, T., Mahasampath, Gowri, Jeyaseelan, Vishali, Nair, Sukesh C., Peter, John Victor

“…Background: The diagnosis of sepsis is challenging in the absence of a gold standard test. Recent studies have explored the role of neutrophil and monocyte…”
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Randomized, Double-Blind, Active Comparator Pharmacodynamic Study of Platelet Inhibition with Crushed and Integral Formulations of Clopidogrel and Ticagrelor in Acute Coronary Syndrome by Perla, Harsha Teja, Thomson, Viji Samuel, Attumalil, Thomas V., Geevar, Tulasi, Alex, Anoop George, Dave, Rutvi G., Nair, Sukesh C., Gowri, S. Mahasampath, Mony, Prem K., George, Paul, Joseph, George

“…Background Crushed formulations of specific antiplatelet agents produce earlier and stronger platelet inhibition. We studied the platelet inhibitory effect of…”
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