Search Results - "Nair, Shiny"

Natural Killer T Cells in Cancer Immunotherapy by Nair, Shiny, Dhodapkar, Madhav V

“…Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid antigens. Following stimulation, NKT cells lead to downstream…”
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Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma by Nair, Shiny, Branagan, Andrew R, Liu, Jun, Boddupalli, Chandra Sekhar, Mistry, Pramod K, Dhodapkar, Madhav V

“…Monoclonal gammopathies developing during the course of Gaucher's disease are reactive against lyso-glucosylceramide (LGL1), which is elevated as a consequence…”
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Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation by Nair, Shiny, Boddupalli, Chandra Sekhar, Verma, Rakesh, Liu, Jun, Yang, Ruhua, Pastores, Gregory M., Mistry, Pramod K., Dhodapkar, Madhav V.

“…Chronic inflammation including B-cell activation is commonly observed in both inherited (Gaucher disease [GD]) and acquired disorders of lipid metabolism…”
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Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma by Richter, Joshua, Neparidze, Natalia, Zhang, Lin, Nair, Shiny, Monesmith, Tamara, Sundaram, Ranjini, Miesowicz, Fred, Dhodapkar, Kavita M., Dhodapkar, Madhav V.

“…Natural killer T (iNKT) cells can help mediate immune surveillance against tumors in mice. Prior studies targeting human iNKT cells were limited to therapy of…”
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Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets by Mukhopadhyay, Sangita, Nair, Shiny, Ghosh, Sudip

“…Abstract Tuberculosis (TB) remains a major health problem worldwide. Attempts to control this disease have proved difficult owing to our poor understanding of…”
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Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy by Boddupalli, Chandra Sekhar, Nair, Shiny, Belinsky, Glenn, Gans, Joseph, Teeple, Erin, Nguyen, Tri-Hung, Mehta, Sameet, Guo, Lilu, Kramer, Martin L, Ruan, Jiapeng, Wang, Honggge, Davison, Matthew, Kumar, Dinesh, Vidyadhara, D J, Zhang, Bailin, Klinger, Katherine, Mistry, Pramod K

“…Neuronopathic Gaucher disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in and buildup of glycosphingolipids in lysosomes…”
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Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma by Nair, Shiny, Branagan, Andrew R., Liu, Jun, Boddupalli, Chandra Sekhar, Mistry, Pramod K., Dhodapkar, Madhav V.

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Glutathione-Redox Balance Regulates c-rel-Driven IL-12 Production in Macrophages: Possible Implications in Antituberculosis Immunotherapy by Alam, Kaiser, Ghousunnissa, Sheikh, Nair, Shiny, Valluri, Vijaya Lakshmi, Mukhopadhyay, Sangita

“…The glutathione-redox balance, expressed as the ratio of intracellular reduced glutathione (GSH) and oxidized glutathione, plays an important role in…”
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Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis by Khan, Nooruddin, Alam, Kaiser, Nair, Shiny, Valluri, Vijaya Lakshmi, Murthy, Kolluri J R, Mukhopadhyay, Sangita

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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VavCre mediated conditional deletion of in mice recapitulates human Gaucher disease type 1, a platform to investigate the role of myeloid cells and altered hematopoiesis by Nair, Shiny, Belinsky, Glenn, Mistry, Pramod K.

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VavCre mediated conditional deletion of Gba in mice recapitulates human Gaucher disease type 1, a platform to investigate the role of myeloid cells and altered hematopoiesis by Nair, Shiny, Belinsky, Glenn, Mistry, Pramod K.

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The PPE18 protein of Mycobacterium tuberculosis inhibits NF-κB/rel-mediated proinflammatory cytokine production by upregulating and phosphorylating suppressor of cytokine signaling 3 protein by Nair, Shiny, Pandey, Akhilesh Datt, Mukhopadhyay, Sangita

“…Mycobacterium tuberculosis bacteria are known to suppress proinflammatory cytokines like IL-12 and TNF-α for a biased Th2 response that favors a successful…”
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The clinical spectrum of SARS-CoV-2 infection in Gaucher disease: Effect of both a pandemic and a rare disease that disrupts the immune system by Narayanan, Praveena, Nair, Shiny, Balwani, Manisha, Malinis, Maricar, Mistry, Pramod

“…The impact of SARS-CoV-2 in rare disease populations has been underreported. Gaucher disease (GD) is a prototype rare disease that shares with SARS-CoV-2 a…”
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Glucosylsphingosine but not Saposin C, is the target antigen in Gaucher disease-associated gammopathy by Nair, Shiny, Bar, Noffar, Xu, Mina L., Dhodapkar, Madhav, Mistry, Pramod K.

“…In Gaucher disease type 1 (GD1), genetic deficiency of lysosomal glucocerebrosidase results in the accumulation of glucosylceramide and glucosylsphingosine…”
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Severe pulmonary arterial hypertension in Gaucher disease type 1 by Basiri, Mohsen, Ruan, Jiapeng, Nair, Shiny, Guo, Lilu, Mistry, Pramod K.

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Single cell resolution of neurodegeneration in Gaucher disease by Nair, Shiny, Belinsky, Glenn, Ruan, Jiapeng, Basiri, Mohsen, Klinger, Katherine W., Mistry, Pramod K.

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The risk of hepatocellular carcinoma is markedly increased in Gaucher disease by Basiri, Mohsen, Ruan, Jiapeng, Nair, Shiny, Lau, Heather A., Mistry, Pramod K., Taddei, Tamar

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Delineating the role of myeloid cells and brain microglia in Gaucher disease by Boddupalli, Venkata, Nair, Shiny, Belinsky, Glenn, Mehta, Sameet, Mistry, Pramod

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Passivation of organic field effect transistor with photopatterned Parylene to improve environmental stability by Nair, Shiny, Kathiresan, M., Mukundan, T., Natarajan, V.

“…Unprotected organic electronic devices suffer from degradation as they are susceptible to water, oxygen and other environmental elements present in ambient…”
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Patterned water dispersible conducting polymer electrode in organic thin film transistor through a parylene lift-off process by Nair, Shiny, Kathiresan, M., Mukundan, T.

“…•Synthesis of nanostructured Polyaniline: Polystyrene sulphonic acid composite.•High conductivity of the composite by secondary doping with dichloroacetic…”
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