Search Results - "Nair, Raji E"
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Reversing Tumor Immune Suppression with Intratumoral IL-12: Activation of Tumor-Associated T Effector/Memory Cells, Induction of T Suppressor Apoptosis, and Infiltration of CD8+ T Effectors
Published in The Journal of immunology (1950) (15-11-2006)“…A single intratumoral injection of IL-12 and GM-CSF-loaded slow-release microspheres induces T cell-dependent eradication of established primary and metastatic…”
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The flavonoid, quercetin, differentially regulates Th-1 (IFNγ) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells
Published in Biochimica et biophysica acta (16-12-2002)“…Flavonoids are plant metabolites that are dietary antioxidants and exert significant anti-tumor, anti-allergic, anti-inflammatory and anti-viral effects. It is…”
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Chronic chemoimmunotherapy achieves cure of spontaneous murine mammary tumors via persistent blockade of posttherapy counter-regulation
Published in The Journal of immunology (1950) (15-10-2011)“…Intratumoral delivery of IL-12 and GM-CSF induces local and systemic antitumor CD8(+) T cell activation and tumor kill. However, the effector response is…”
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Chronic Immune Therapy Induces a Progressive Increase in Intratumoral T Suppressor Activity and a Concurrent Loss of Tumor-Specific CD8+ T Effectors in her-2/neu Transgenic Mice Bearing Advanced Spontaneous Tumors
Published in The Journal of immunology (1950) (15-06-2006)“…A single intratumoral injection of IL-12 and GM-CSF-encapsulated microspheres induces the complete regression of advanced spontaneous tumors in her-2/neu…”
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IL-12 + GM-CSF microsphere therapy induces eradication of advanced spontaneous tumors in her-2/neu transgenic mice but fails to achieve long-term cure due to the inability to maintain effector T-cell activity
Published in Journal of immunotherapy (1997) (2006)“…A single intratumoral injection of interleukin-12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres induced the regression of…”
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Assay of tubercular antibody, circulating free and immune complexed antigen in the diagnosis of pulmonary tuberculosis
Published in Indian journal of clinical biochemistry (01-07-2001)“…Analysis of tubercular antibody, circulating free and immune complexed antigen (CIC-Ag) was done in confimed pulmonary tuberculosis sera by ELISA, using ES-31…”
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Mycobacterium tuberculosis H37Ra ESAS-7—An excretory-secretory antigen fraction of immunodiagnostic potential in pulmonary tuberculosis
Published in Indian journal of clinical biochemistry (01-07-1998)“…A mycobacterial excretory-secretory protein fraction ESAS-7 purified by 50% ammonium sulphate precipitation followed by SDS-PAGE fractionation was evaluated by…”
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Isolation ofMycobacterium Tuberculosis 31 kDa antigen protein of diagnostic interest from culture filtrate using anti-ES-31 antibody by affinity chromatography
Published in Indian journal of clinical biochemistry (01-01-2001)“…Proteins secreted into the culture medium byMycobacterium tuberculosis (M. tb) are shown to be source of antigens of immunodiagnostic interest. Anin vitro…”
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Characterization of cytokine-encapsulated controlled-release microsphere adjuvants
Published in Cancer biotherapy & radiopharmaceuticals (01-12-2004)“…Controlled-release, injectable polymer microspheres provide a clinically feasible alternative to gene-modification for the local, sustained delivery of…”
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Chronic Chemoimmunotherapy Achieves Cure of Spontaneous Murine Mammary Tumors via Persistent Blockade of Post-therapy Counter-regulation
Published in The Journal of immunology (1950) (09-09-2011)“…Intratumoral delivery of Interleukin-12 (IL-12) and Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) induces local and systemic antitumor CD8+ T-cell…”
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Chronic Immune Therapy Induces a Progressive Increase in Intratumoral T Suppressor Activity and a Concurrent Loss of Tumor-Specific CD8 super(+) T Effectors in her-2/neu Transgenic Mice Bearing Advanced Spontaneous Tumors
Published in Journal of Immunology (01-06-2006)“…A single intratumoral injection of IL-12 and GM-CSF-encapsulated microspheres induces the complete regression of advanced spontaneous tumors in her-2/neu…”
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Reversing Tumor Immune Suppression with Intratumoral IL-12: Activation of Tumor-Associated T Effector/Memory Cells, Induction of T Suppressor Apoptosis, and Infiltration of CD8 super(+) T Effectors
Published in Journal of Immunology (01-11-2006)“…A single intratumoral injection of IL-12 and GM-CSF-loaded slow-release microspheres induces T cell-dependent eradication of established primary and metastatic…”
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Isolation and Characterization of a 31 kDa Mycobacterial Antigen from Tuberculous Sera and its Identification with in vitro Released Culture Filtrate Antigen of Mtb H37Ra Bacilli
Published in Scandinavian journal of infectious diseases (2000)“…Antigens released in vivo are of considerable interest in the immunodiagnosis of infectious diseases. Circulating antigen was isolated from bacteriologically…”
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Purification and characterization of a 31 kDa mycobacterial excretory-secretory antigenic protein with a diagnostic potential in pulmonary tuberculosis
Published in Indian journal of chest diseases & allied sciences (01-04-2001)“…Proteins secreted into the culture medium by Mycobacterium tuberculosis are shown to be a source of antigens of immunodiagnostic importance. In our earlier…”
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Sero-reactivity of two different antigenic protein fractions of M.tb H37Ra excretory-secretory antigen in pulmonary and extra-pulmonary tuberculosis
Published in Journal of communicable diseases (01-06-2001)“…Excretory-secretory proteins of Mycobacterium tuberculosis H37Ra, have been of diagnostic interest in pulmonary (PTB) and extrapulmonary tuberculosis (EPTB)…”
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