Search Results - "Nair, Prabha. D."
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Effect of stiffness of chitosan-hyaluronic acid dialdehyde hydrogels on the viability and growth of encapsulated chondrocytes
Published in International journal of biological macromolecules (01-11-2017)“…Substrate elasticity or stiffness can influence the phenotypic and functional characteristics of chondrocytes. This work aimed to study the effect of varying…”
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2
Tissue‐engineered islet‐like cell clusters generated from adipose tissue‐derived stem cells on three‐dimensional electrospun scaffolds can reverse diabetes in an experimental rat model and the role of porosity of scaffolds on cluster differentiation
Published in Journal of biomedical materials research. Part A (01-03-2020)“…In the current study, three‐dimensional (3D) nanofibrous scaffolds with pore sizes in the range of 24–250 μm and 24–190 μm were fabricated via a two‐step…”
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3D-printed biphasic scaffolds for the simultaneous regeneration of osteochondral tissues
Published in Biomedical materials (Bristol) (01-09-2021)“…Osteochondral tissue engineering (OCTE) involves the simulation of highly complex tissues with disparate biomechanical properties. OCTE is regarded as the best…”
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4
Generation of Pancreatic Hormone‐Expressing Islet‐Like Cell Aggregates from Murine Adipose Tissue‐Derived Stem Cells
Published in Stem cells (Dayton, Ohio) (01-08-2009)“…The success of cell replacement therapy for diabetes depends on the availability and generation of an adequate number of islets, preferably from an autologous…”
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Biomimeticity in tissue engineering scaffolds through synthetic peptide modifications-Altering chemistry for enhanced biological response
Published in Journal of biomedical materials research. Part A (01-02-2011)“…Biomimetic and bioactive biomaterials are desirable as tissue engineering scaffolds by virtue of their capability to mimic natural environments of the…”
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6
Bioactive nano‐fibrous scaffold for vascularized craniofacial bone regeneration
Published in Journal of tissue engineering and regenerative medicine (01-03-2018)“…There has been a growing demand for bone grafts for correction of bone defects in complicated fractures or tumours in the craniofacial region. Soft flexible…”
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Autologous Culture Expanded Iliac Crest Chondrocytes in Chitosan Hyaluronic Acid Dialdehyde Gel Regenerate Caprine Growth Plate
Published in Regenerative engineering and translational medicine (01-09-2023)“…Purpose Allogenic and autologous chondrocytes have been used to reconstitute damaged growth plates in small and large animals with variable success. We…”
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Assessing the 3D Printability of an Elastomeric Poly(caprolactone-co-lactide) Copolymer as a Potential Material for 3D Printing Tracheal Scaffolds
Published in ACS omega (01-03-2022)“…The advent of 3D printing technology has made remarkable progress in the field of tissue engineering. Yet, it has been challenging to reproduce the desired…”
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Matrix remodeling and mechanotransduction in in vitro chondrogenesis: Implications towards functional stem cell‐based cartilage tissue engineering
Published in Engineering reports (Hoboken, N.J.) (01-05-2020)“…Stem cell‐based cartilage regeneration strategies take benefits from functional tissue engineering concepts that effectively exploit cells native…”
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Human blood vessel-derived endothelial progenitors for endothelialization of small diameter vascular prosthesis
Published in PloS one (05-11-2009)“…Coronary bypass graft failure as a result of acute thrombosis and intimal hyperplasia has been the major challenge in surgical procedures involving…”
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A 3D biodegradable protein based matrix for cartilage tissue engineering and stem cell differentiation to cartilage
Published in Journal of materials science. Materials in medicine (01-12-2009)“…A protein based 3D porous scaffold is fabricated by blending gelatin and albumin. The biomimetic biodegradable gelatin, promoted good cell adhesion and its…”
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Reversal of experimental diabetes in mice by transplantation of neo-islets generated from human amnion-derived mesenchymal stromal cells using immuno-isolatory macrocapsules
Published in Cytotherapy (Oxford, England) (01-12-2010)“…Abstract Background aims The ethical and biologic limitations with current sources of stem cells have resulted in a quest to look for alternative sources of…”
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13
Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice
Published in PloS one (07-06-2011)“…Type 1 Diabetes Mellitus is caused by auto immune destruction of insulin producing beta cells in the pancreas. Currently available treatments include…”
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Polycaprolactone-laponite composite scaffold releasing strontium ranelate for bone tissue engineering applications
Published in Colloids and surfaces, B, Biointerfaces (01-07-2016)“…[Display omitted] •A scaffold containing dual osteoinductive factors laponite and strontium ranelate.•Complex of strontium ranelate with laponite through…”
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Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers
Published in Journal of biomaterials science. Polymer ed. (02-05-2020)“…Generation of full thickness skin equivalent models is of increasing interest in tissue engineering because of the limitations inherent to current models. In…”
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(Citric acid-co-polycaprolactone triol) polyester: A biodegradable elastomer for soft tissue engineering
Published in Biomatter (Austin, TX) (01-07-2011)“…Tissue engineering holds enormous challenges for materials science, wherein the ideal scaffold to be used is expected to be biocompatible, biodegradable and…”
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Enhanced survival and function of islet-like clusters differentiated from adipose stem cells on a three-dimensional natural polymeric scaffold: an in vitro study
Published in Tissue engineering. Part A (01-05-2014)“…Autologous adipose stem cells owing to its pluripotent nature offer a valuable source for pancreatic beta cell replacement in the treatment of diabetes…”
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18
Scaffolds in vascular regeneration: current status
Published in Vascular health and risk management (01-01-2015)“…An ideal vascular substitute, especially in <6 mm diameter applications, is a major clinical essentiality in blood vessel replacement surgery. Blood vessels…”
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A nonadherent chitosan-polyvinyl alcohol absorbent wound dressing prepared via controlled freeze-dry technology
Published in International journal of biological macromolecules (01-05-2020)“…In modern-day 21st century, the demand has increased for absorbent dressings that are nonadherent and maintain structural integrity without shedding lint in…”
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Cytocompatibility studies of mouse pancreatic islets on gelatin - PVP semi IPN scaffolds in vitro: Potential implication towards pancreatic tissue engineering
Published in Islets (01-11-2010)“…Type 1 diabetes is a chronic disorder that results due to auto immune destruction of insulin producing cells, which leads to hyperglycemia in the blood. The…”
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