Search Results - "Nair, Manitha B."

Biomimetic composite scaffolds containing bioceramics and collagen/gelatin for bone tissue engineering - A mini review by Kuttappan, Shruthy, Mathew, Dennis, Nair, Manitha B.

“…Bone is a natural composite material consisting of an organic phase (collagen) and a mineral phase (calcium phosphate, especially hydroxyapatite). The strength…”
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Dual release of growth factor from nanocomposite fibrous scaffold promotes vascularisation and bone regeneration in rat critical sized calvarial defect by Kuttappan, Shruthy, Mathew, Dennis, Jo, Jun-ichiro, Tanaka, Ryusuke, Menon, Deepthy, Ishimoto, Takuya, Nakano, Takayoshi, Nair, Shantikumar V., Nair, Manitha B., Tabata, Yasuhiko

“…[Display omitted] A promising strategy for augmenting bone formation involves the local delivery of multiple osteoinductive and vasculogenic growth factors…”
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Bioinspired Composite Matrix Containing Hydroxyapatite–Silica Core–Shell Nanorods for Bone Tissue Engineering by A, Anitha, Menon, Deepthy, T. B, Sivanarayanan, Koyakutty, Manzoor, Mohan, Chandini C, Nair, Shantikumar V, Nair, Manitha B

“…Development of multifunctional bioinspired scaffolds that can stimulate vascularization and regeneration is necessary for the application in bone tissue…”
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Poly(L-lactic acid) nanofibers containing Cissus quadrangularis induced osteogenic differentiation in vitro by Parvathi, K, Krishnan, Amit G., Anitha, A, Jayakumar, R., Nair, Manitha B.

“…Cissus quadrangularis (CQ) is known as “bone setter” in Ayurvedic Medicine because of its ability to promote fracture healing. Polymers incorporated with CQ at…”
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Electrospun Yarn Reinforced NanoHA Composite Matrix as a Potential Bone Substitute for Enhanced Regeneration of Segmental Defects by Anitha, A, Joseph, John, Menon, Deepthy, Nair, Shantikumar V, Nair, Manitha B

“…Nanohydroxyapatite (nanoHA) is a well-established synthetic bone substitute with excellent osteoconduction and osteointegration. However, brittleness coupled…”
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Nanofibrous yarn reinforced HA-gelatin composite scaffolds promote bone formation in critical sized alveolar defects in rabbit model by Manju, V, Anitha, A, Menon, Deepthy, Iyer, Subramaniya, Nair, Shantikumar V, Nair, Manitha B

“…Alveolar ridge resorption and crestal bone loss necessitate the use of bone graft substitutes for dental rehabilitation. The aim of this study was to compare…”
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Successful Reduction of Neointimal Hyperplasia on Stainless Steel Coronary Stents by Titania Nanotexturing by Cherian, Aleena Mary, Joseph, John, Nair, Manitha B, Nair, Shantikumar V, Maniyal, Vijayakumar, Menon, Deepthy

“…Bare metal stents (BMSs) of stainless steel (SS) were surface engineered to develop nanoscale titania topography using a combination of physical vapor…”
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A triphasic ceramic-coated porous hydroxyapatite for tissue engineering application by Nair, Manitha B., Suresh Babu, S., Varma, H.K., John, Annie

“…Scaffolds which encourage the incorporation of a cell source for tissue engineering applications are critical determinants for clinical defects. Over the…”
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Triphasic ceramic coated hydroxyapatite as a niche for goat stem cell-derived osteoblasts for bone regeneration and repair by Nair, Manitha B., Varma, H. K., John, Annie

“…Current treatment strategies for the repair or replacement of bone use synthetic implants with stem cells and their progeny––a new approach to address unmet…”
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Composite hydrogel of chitosan–poly(hydroxybutyrate-co-valerate) with chondroitin sulfate nanoparticles for nucleus pulposus tissue engineering by Nair, Manitha B., Baranwal, Gaurav, Vijayan, Prajuna, Keyan, Kripa S., Jayakumar, R.

“…[Display omitted] •An injectable composite hydrogel of chitosan–poly(hydroxybutyrate-co-valerate) with chondroitin sulfate nanoparticles was developed.•The…”
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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis by Krishnan, Amit G, Biswas, Raja, Menon, Deepthy, Nair, Manitha B

“…There is an increased demand for an ideal biodegradable biomaterial that eradicates infection, while concurrently promoting tissue regeneration in…”
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Bioinspired nanocomposite fibrous scaffold mediated delivery of ONO-1301 and BMP2 enhance bone regeneration in critical sized defect by Kuttappan, Shruthy, Jo, Jun-ichiro, Sabu, Chinchu K., Menon, Deepthy, Tabata, Yasuhiko, Nair, Manitha B.

“…Treatment aiming to enhance bone tissue regeneration can benefit from multiple growth factor or small molecule delivery. In the present study, the objective…”
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Effect of wheat gluten on improved thermal cross-linking and osteogenesis of hydroxyapatite-gelatin composite scaffolds by Sri Ramakrishnan, Lalitha, PS, Unnikrishnan, Sabu, Chinchu K, Krishnan, Amit G, Nair, Manitha B

“…Promising strategies to stabilize gelatin or collagen include glutaraldehyde-based chemical cross-linking or dehydrothermal treatment at different temperatures…”
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Infection and tissue engineering in segmental bone defects — a mini review by Nair, Manitha B, Kretlow, James D, Mikos, Antonios G, Kasper, F Kurtis

“…Research highlights ► We review osteomyelitis and implants for local antibiotic delivery to address it. ► We highlight a need for a system to eliminate…”
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Relevance of fiber integrated gelatin-nanohydroxyapatite composite scaffold for bone tissue regeneration by Shamaz, Bibi Halima, Anitha, A, Vijayamohan, Manju, Kuttappan, Shruthy, Nair, Shantikumar, Nair, Manitha B

“…Porous nanohydroxyapatite (nanoHA) is a promising bone substitute, but it is brittle, which limits its utility for load bearing applications. To address this…”
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BMP2 expressing genetically engineered mesenchymal stem cells on composite fibrous scaffolds for enhanced bone regeneration in segmental defects by Kuttappan, Shruthy, Anitha, A., Minsha, M.G., Menon, Parvathy M., Sivanarayanan, T.B., Vijayachandran, Lakshmi Sumitra, Nair, Manitha B.

“…The treatment of critical sized bone defect remains a significant challenge in orthopedics. The objective of the study is to evaluate the effect of the…”
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Evaluation of osteoinductive and endothelial differentiation potential of Platelet-Rich Plasma incorporated Gelatin-Nanohydroxyapatite Fibrous Matrix by J, Anjana, Kuttappan, Shruthy, Keyan, Kripa S., Nair, Manitha B.

“…In this study, platelet-rich plasma (PRP) was incorporated into gelatin-nanohydroxyapatite fibrous scaffold in two forms (PRP gel as coating on the scaffold…”
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Superhydrophilic multifunctional nanotextured titanium dental implants: in vivo short and long-term response in a porcine model by Mathew, Anil, Abraham, Silpa, Stephen, Shamilin, Babu, Anna Serene, Gowd, Siddaramana G, Vinod, Vivek, Biswas, Raja, Nair, Manitha B, Unni, A K K, Menon, Deepthy

“…Current clinical demand in dental implantology is for a multifunctional device with optimum mechanical properties, improved biocompatibility and bioactivity,…”
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Stable Titania Nanostructures on Stainless Steel Coronary Stent Surface for Enhanced Corrosion Resistance and Endothelialization by Mohan, Chandini C., Cherian, Aleena Mary, Kurup, Sujish, Joseph, John, Nair, Manitha B., Vijayakumar, Maniyal, Nair, Shantikumar V., Menon, Deepthy

“…Stainless steel (SS) coronary stents continue to present risk of in‐stent restenosis that impact its long term safety and efficacy. The present work focuses on…”
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Reconstruction of goat femur segmental defects using triphasic ceramic-coated hydroxyapatite in combination with autologous cells and platelet-rich plasma by Nair, Manitha B., Varma, H.K., Menon, K.V., Shenoy, Sachin J., John, Annie

“…Segmental bone defects resulting from trauma or pathology represent a common and significant clinical problem. In this study, a triphasic ceramic (calcium…”
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