Search Results - "Nair, K."
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1
Free-living and laboratory gait characteristics in patients with multiple sclerosis
Published in PloS one (01-05-2018)“…Wearable sensors offer the potential to bring new knowledge to inform interventions in patients affected by multiple sclerosis (MS) by thoroughly quantifying…”
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2
Sustainable treatment of paint industry wastewater: Current techniques and challenges
Published in Journal of environmental management (15-10-2021)“…Paint manufacturing industries produce wastewater containing high chemical oxygen demand and turbidity, besides organic matter, suspended solids, and heavy…”
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3
Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function
Published in Diabetes (New York, N.Y.) (01-01-2010)“…Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function Helen Karakelides , Brian A. Irving , Kevin R. Short , Peter…”
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4
Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry
Published in Cell metabolism (06-10-2015)“…Exercise provides many health benefits, including improved metabolism, cardiovascular health, and cognition. We have shown previously that FNDC5, a type I…”
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5
Hormonal and Metabolic Changes of Aging and the Influence of Lifestyle Modifications
Published in Mayo Clinic proceedings (01-03-2021)“…Increased life expectancy combined with the aging baby boomer generation has resulted in an unprecedented global expansion of the elderly population. The…”
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Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools
Published in Nucleic acids research (04-01-2016)“…The Metabolomics Workbench, available at www.metabolomicsworkbench.org, is a public repository for metabolomics metadata and experimental data spanning various…”
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7
Altered mitochondrial function in insulin-deficient and insulin-resistant states
Published in The Journal of clinical investigation (31-08-2018)“…Diabetes profoundly alters fuel metabolism; both insulin deficiency and insulin resistance are characterized by inefficient mitochondrial coupling and…”
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8
FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy
Published in Diabetes (New York, N.Y.) (01-03-2019)“…Insulin deficiency and uncontrolled diabetes lead to a catabolic state with decreased muscle strength, contributing to disease-related morbidity. FoxO…”
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9
Structural framework to address variant-gene relationship in primary open-angle glaucoma
Published in Vision research (Oxford) (01-01-2025)“…Primary open-angle glaucoma (POAG) is a complex, multifactorial disease leading to progressive optic neuropathy and irreversible vision loss. Genome-Wide…”
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10
Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group
Published in Clinical nutrition (Edinburgh, Scotland) (2014)“…Summary The aging process is associated with gradual and progressive loss of muscle mass along with lowered strength and physical endurance. This condition,…”
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11
Aging muscle
Published in The American journal of clinical nutrition (01-05-2005)“…Age causes structural and functional changes in skeletal muscle in a wide range of species, including humans. Muscle changes in humans start in the fourth…”
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12
Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans
Published in Cell metabolism (07-03-2017)“…The molecular transducers of benefits from different exercise modalities remain incompletely defined. Here we report that 12 weeks of high-intensity aerobic…”
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13
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
Published in Nature (London) (22-01-2015)“…Structural and biochemical studies show that the biosynthesis of the food preservative nisin involves the tRNA-dependent glutamylation of serine and threonine…”
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14
Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens
Published in PLoS biology (01-07-2015)“…Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom is that natural selection will remove highly lethal pathogens if host…”
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15
Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes
Published in Chemical reviews (26-04-2017)“…Lanthipeptides are ribosomally synthesized and post-translationally modified peptides (RiPPs) that display a wide variety of biological activities, from…”
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16
Time‐Restricted Eating Effects on Body Composition and Metabolic Measures in Humans who are Overweight: A Feasibility Study
Published in Obesity (Silver Spring, Md.) (01-05-2020)“…Objective In contrast to intentionally restricting energy intake, restricting the eating window may be an option for treating obesity. By comparing…”
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17
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
Published in Nature communications (14-06-2021)“…Cataract is the leading cause of blindness among the elderly worldwide and cataract surgery is one of the most common operations performed in the United…”
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18
GDF15 mediates the effects of metformin on body weight and energy balance
Published in Nature (London) (20-02-2020)“…Metformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk 1 , 2 . More than 60% of this…”
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A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy
Published in Cell (07-12-2012)“…PGC-1α is a transcriptional coactivator induced by exercise that gives muscle many of the best known adaptations to endurance-type exercise but has no effects…”
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20
Endurance Exercise as a Countermeasure for Aging
Published in Diabetes (New York, N.Y.) (01-11-2008)“…Endurance Exercise as a Countermeasure for Aging Ian R. Lanza , Daniel K. Short , Kevin R. Short , Sreekumar Raghavakaimal , Rita Basu , Michael J. Joyner ,…”
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