Search Results - "Nair, Anita"

Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations – a PEARRL review by Price, Daniel J., Ditzinger, Felix, Koehl, Niklas J., Jankovic, Sandra, Tsakiridou, Georgia, Nair, Anita, Holm, René, Kuentz, Martin, Dressman, Jennifer B., Saal, Christoph

“…Objectives Supersaturating formulations hold great promise for delivery of poorly soluble active pharmaceutical ingredients (APIs). To profit from…”
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Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy by McHenry, Christina L, Hübner, Christian A, Gal, Andreas, Thompson, Debra A, Wissinger, Bernd, Rüschendorf, Franz, Heckenlively, John, Schmid, Eduard, Utermann, Gerd, Janecke, Andreas R, Nair, Anita R, Nürnberg, Peter, Becker, Christian

“…We identified three consanguineous Austrian kindreds with 15 members affected by autosomal recessive childhood-onset severe retinal dystrophy, a genetically…”
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Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies by Ditzinger, Felix, Price, Daniel J, Nair, Anita, Becker-Baldus, Johanna, Glaubitz, Clemens, Dressman, Jennifer B, Saal, Christoph, Kuentz, Martin

“…Amorphous formulation technologies to improve oral absorption of poorly soluble active pharmaceutical ingredients (APIs) have become increasingly prevalent…”
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Anaesthetising an infant with acrocallosal syndrome: An unusual case by Hosdurg, Bharathi, Nair, Anita, Simha, Jayashree, Sriramanan, Suma

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Residual Neuromuscular Blockade Affects Postoperative Pulmonary Function by GOPALAIAH VENKATESH KUMAR, ANITA PRAMOD NAIR, HANUMAN SRINIVASA MURTHY, KOPPA RAMEGOWDA JALAJA, RAMACHANDRA, Karnate, PARAMESHWARA, Gundappa

“…Residual neuromuscular blockade (RNMB) is known to be associated with respiratory complications in the postoperative period after muscle relaxant usage. The…”
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Occupational therapists' identification, assessment, and treatment of unilateral spatial neglect during stroke rehabilitation in Canada by MENON-NAIR, Anita, KORNER-BITENSKY, Nicol, OGOURTSOVA, Tatiana

“…Unilateral spatial neglect (USN) is a disabling feature of stroke, and its identification and management are critical for optimizing patient outcomes. This…”
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A Prospective Study of Seroconversion Post Covishield Vaccination in COVID-19 Warriors by Anita Balakrishnan Nair, Shahriar Bahman Roushani, Deepika Shivaji Bhalerao, Sanjeev Gopal Kulkarni, Vaibhav Vitthalrao Rajhans, Anagha Subhash Vaidya, Savita Baban Tajane

“…Introduction: During the Coronavirus Disease 2019 (COVID-19) pandemic in India, two vaccinees were predominantly administered to prevent the spread of the…”
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MERTK Arginine-844-Cysteine in a Patient with Severe Rod-Cone Dystrophy: Loss of Mutant Protein Function in Transfected Cells by McHenry, Christina L, Liu, Yuhui, Feng, Wei, Nair, Anita R, Feathers, Kecia L, Ding, Xiaoling, Gal, Andreas, Vollrath, Douglas, Sieving, Paul A, Thompson, Debra A

“…Mutations in the MERTK gene are responsible for retinal degeneration in the Royal College of Surgeons (RCS) rat and are a cause of human autosomal recessive…”
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Culture Positivity of Cerebrospinal Fluid by Automated Blood Culture System in Neonates: A Cross-sectional Study from Loni, Maharashtra, India by Tajane, Savita Baban, Vaidya, Anagha Subhashchandra, Bhalerao, Deepika Shivaji, Roushani, Shahriar Bahman, Kulkarni, Sanjeev Gopalrao, Rajhans, aibhav Vitthalrao, Nair, Anita Balakrishnan

“…Introduction: Bacterial meningitis especially in neonates remains a major cause of mortality and long term health sequelae. There is a need for periodic…”
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Ameliorative effect of vitamin E on aflatoxin-induced lipid peroxidation in the testis of mice by VERMA, R. J, NAIR, Anita

“…To evaluate the ameliorative effect of vitamin E on aflatoxin-induced lipid peroxidation in the testis. Adult male albino mice were orally administered 25 or…”
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Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations by Price, Daniel J., Nair, Anita, Kuentz, Martin, Dressman, Jennifer, Saal, Christoph

“…Supersaturating formulations are widely used to improve the oral bioavailability of poorly soluble drugs. However, supersaturated solutions are…”
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Vitamin E ameliorates aflatoxin-induced biochemical changes in the testis of mice by VERMA, R. J, NAIR, Anita

“…To assess the effect of aflatoxin on biochemical changes in the testis of mice and the possibility of amelioration by vitamin E treatment. Adult male albino…”
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Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review by Ditzinger, Felix, Price, Daniel J., Ilie, Alexandra‐Roxana, Köhl, Niklas J., Jankovic, Sandra, Tsakiridou, Georgia, Aleandri, Simone, Kalantzi, Lida, Holm, René, Nair, Anita, Saal, Christoph, Griffin, Brendan, Kuentz, Martin

“…Objectives This review highlights aspects of drug hydrophobicity and lipophilicity as determinants of different oral formulation approaches with specific focus…”
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Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipitation by Price, Daniel J., Nair, Anita, Becker-Baldus, Johanna, Glaubitz, Clemens, Kuentz, Martin, Dressman, Jennifer, Saal, Christoph

“…Mesoporous silica has emerged as an enabling formulation for poorly soluble active pharmaceutical ingredients (APIs). Unlike other formulations, mesoporous…”
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Application of the solubility parameter concept to assist with oral delivery of poorly water‐soluble drugs – a PEARRL review by Jankovic, Sandra, Tsakiridou, Georgia, Ditzinger, Felix, Koehl, Niklas J., Price, Daniel J., Ilie, Alexandra‐Roxana, Kalantzi, Lida, Kimpe, Kristof, Holm, René, Nair, Anita, Griffin, Brendan, Saal, Christoph, Kuentz, Martin

“…Objectives Solubility parameters have been used for decades in various scientific fields including pharmaceutics. It is, however, still a field of active…”
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Translating Thakazhi by Nair, Anita

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Biowaiver monographs for immediate release solid oral dosage forms: efavirenz by Cristofoletti, Rodrigo, Nair, Anita, Abrahamsson, Bertil, Groot, D W, Kopp, Sabine, Langguth, Peter, Polli, James E, Shah, Vinod P, Dressman, Jennifer B

“…Literature data pertaining to the decision to allow a waiver of in vivo bioequivalence testing for the approval of immediate-release (IR) solid oral dosage…”
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Biowaiver monograph for immediate-release solid oral dosage forms: acetylsalicylic acid by Dressman, Jennifer B, Nair, Anita, Abrahamsson, Bertil, Barends, Dirk M, Groot, D W, Kopp, Sabine, Langguth, Peter, Polli, James E, Shah, Vinod P, Zimmer, Markus

“…A biowaiver monograph for acetylsalicylic acid (ASA) is presented. Literature and experimental data indicate that ASA is a highly soluble and highly permeable…”
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Biowaiver monographs for immediate release solid oral dosage forms: amodiaquine hydrochloride by Nair, Anita, Abrahamsson, Bertil, Barends, Dirk M, Groot, D W, Kopp, Sabine, Polli, James E, Shah, Vinod P, Dressman, Jennifer B

“…The present monograph reviews data relevant to applying the biowaiver procedure for the approval of immediate release (IR) multisource solid dosage forms…”
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Biowaiver monographs for immediate-release solid oral dosage forms: primaquine phosphate by Nair, Anita, Abrahamsson, Bertil, Barends, Dirk M, Groot, D W, Kopp, Sabine, Polli, James E, Shah, Vinod P, Dressman, Jennifer B

“…Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage…”
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