Search Results - "Nair, Aisha"

Hypercapnia Inhibits Autophagy and Bacterial Killing in Human Macrophages by Increasing Expression of Bcl-2 and Bcl-xL by Casalino-Matsuda, S Marina, Nair, Aisha, Beitel, Greg J, Gates, Khalilah L, Sporn, Peter H S

“…Hypercapnia, the elevation of CO2 in blood and tissue, commonly develops in patients with advanced lung disease and severe pulmonary infections, and it is…”
Get full text

Hypercapnia impairs lung neutrophil function and increases mortality in murine pseudomonas pneumonia by Gates, Khalilah L, Howell, Heather A, Nair, Aisha, Vohwinkel, Christine U, Welch, Lynn C, Beitel, Greg J, Hauser, Alan R, Sznajder, Jacob I, Sporn, Peter H S

“…Hypercapnia, an elevation of the level of carbon dioxide (CO2) in blood and tissues, is a marker of poor prognosis in chronic obstructive pulmonary disease and…”
Get full text

A role for heat shock factor 1 in hypercapnia‐induced inhibition of inflammatory cytokine expression by Lu, Ziyan, Casalino‐Matsuda, S. Marina, Nair, Aisha, Buchbinder, Anja, Budinger, G. R. Scott, Sporn, Peter H. S., Gates, Khalilah L.

“…Hypercapnia, elevated levels of CO2 in the blood, is a known marker for poor clinical prognosis and is associated with increased mortality in patients…”
Get full text

Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage by Casalino-Matsuda, S Marina, Berdnikovs, Sergejs, Wang, Naizhen, Nair, Aisha, Gates, Khalilah L, Beitel, Greg J, Sporn, Peter H S

“…Hypercapnia, the elevation of CO in blood and tissues, commonly occurs in severe acute and chronic respiratory diseases and is associated with increased risk…”
Get full text

Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and Wound Healing by Wu, Minghua, Melichian, Denisa S, de la Garza, Mauricio, Gruner, Katherine, Bhattacharyya, Swati, Barr, Luke, Nair, Aisha, Shahrara, Shiva, Sporn, Peter H.S, Mustoe, Thomas A, Tourtellotte, Warren G, Varga, John

“…The early growth response gene (Egr-1) codes for a zinc finger transcription factor that has important roles in the regulation of cell growth, differentiation,…”
Get full text

Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A Infection via Akt1 by Casalino-Matsuda, S Marina, Chen, Fei, Gonzalez-Gonzalez, Francisco J, Nair, Aisha, Dib, Sandra, Yemelyanov, Alex, Gates, Khalilah L, Budinger, G R Scott, Beitel, Greg J, Sporn, Peter H S

“…Hypercapnia (HC), elevation of the partial pressure of CO in blood and tissues, is a risk factor for mortality in patients with severe acute and chronic lung…”
Get full text

Hypercapnia Inhibits Host Defense Against Influenza A Virus by Potentiating Virus‐induced Activation of the PI3K/Akt Pathway by Casalino‐Matsuda, Marina, Gonzalez, Francisco, Chi, Monica, Nair, Aisha, Gates, Khalilah, Budinger, Scott, Sporn, Peter

“…Abstract only Rationale Hypercapnia, the elevation of CO 2 in blood and tissue, commonly develops in advanced COPD and is associated with frequent and…”
Get full text

Hypercapnia Alters Expression of Immune Response, Nucleosome Assembly and Lipid Metabolism Genes in Differentiated Human Bronchial Epithelial Cells by Casalino-Matsuda, S. Marina, Wang, Naizhen, Ruhoff, Peder T., Matsuda, Hiroaki, Nlend, Marie C., Nair, Aisha, Szleifer, Igal, Beitel, Greg J., Sznajder, Jacob I., Sporn, Peter H. S.

“…Hypercapnia, the elevation of CO 2 in blood and tissues, commonly occurs in severe acute and chronic respiratory diseases, and is associated with increased…”
Get full text

Myeloid Zfhx3 deficiency protects against hypercapnia-induced suppression of host defense against influenza A virus by Casalino-Matsuda, S Marina, Chen, Fei, Gonzalez-Gonzalez, Francisco J, Matsuda, Hiroaki, Nair, Aisha, Abdala-Valencia, Hiam, Budinger, G R Scott, Dong, Jin-Tang, Beitel, Greg J, Sporn, Peter Hs

“…Hypercapnia, elevation of the partial pressure of CO2 in blood and tissues, is a risk factor for mortality in patients with severe acute and chronic lung…”
Get full text

Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression by Helenius, Iiro Taneli, Nair, Aisha, Bittar, Humberto E Trejo, Sznajder, Jacob I, Sporn, Peter H S, Beitel, Greg J

“…Patients with severe lung disease may develop hypercapnia, elevation of the levels of CO2 in the lungs and blood, which is associated with increased risk of…”
Get more information

Lactate depresses sarcolemmal permeability of Ca 2+ in intact arterial smooth muscle by Barron, John T, Nair, Aisha

“…Elevation of ambient lactate concentration has been shown to alter contractile reactivity of vascular smooth muscle. We tested the hypothesis that lactate…”
Get full text

Lactate depresses sarcolemmal permeability of Ca2+ in intact arterial smooth muscle by Barron, John T, Nair, Aisha

“…Elevation of ambient lactate concentration has been shown to alter contractile reactivity of vascular smooth muscle. We tested the hypothesis that lactate…”
Get full text

Effect of angiotensin II on energetics, glucose metabolism and cytosolic NADH/NAD and NADPH/NADP redox in vascular smooth muscle by Barron, John T, Sasse, Mark F, Nair, Aisha

“…Angiotensin II (AII) is a neurohormone and contractile agonist of vascular smooth muscle that has been shown to be involved in the pathogenesis of vascular…”
Get full text