Search Results - "Naipal, Kishan A T"

Tumor slice culture system to assess drug response of primary breast cancer by Naipal, Kishan A T, Verkaik, Nicole S, Sánchez, Humberto, van Deurzen, Carolien H M, den Bakker, Michael A, Hoeijmakers, Jan H J, Kanaar, Roland, Vreeswijk, Maaike P G, Jager, Agnes, van Gent, Dik C

“…The high incidence of breast cancer has sparked the development of novel targeted and personalized therapies. Personalization of cancer treatment requires…”
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Ex vivo assays to predict enhanced chemosensitization by hyperthermia in urothelial cancer of the bladder by van den Tempel, Nathalie, Naipal, Kishan A T, Raams, Anja, van Gent, Dik C, Franckena, Martine, Boormans, Joost L, Kanaar, Roland

“…Bladder cancer (urothelial carcinoma) is a common malignancy characterized by high recurrence rates and intense clinical follow-up, indicating the necessity…”
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Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer by Naipal, Kishan A T, Raams, Anja, Bruens, Serena T, Brandsma, Inger, Verkaik, Nicole S, Jaspers, Nicolaas G J, Hoeijmakers, Jan H J, van Leenders, Geert J L H, Pothof, Joris, Kanaar, Roland, Boormans, Joost, van Gent, Dik C

“…Bladder cancer has a high incidence with significant morbidity and mortality. Attenuated expression of the DNA damage response protein Xeroderma Pigmentosum…”
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Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment by Naipal, Kishan A T, Verkaik, Nicole S, Ameziane, Najim, van Deurzen, Carolien H M, Ter Brugge, Petra, Meijers, Matty, Sieuwerts, Anieta M, Martens, John W, O'Connor, Mark J, Vrieling, Harry, Hoeijmakers, Jan H J, Jonkers, Jos, Kanaar, Roland, de Winter, Johan P, Vreeswijk, Maaike P, Jager, Agnes, van Gent, Dik C

“…Poly(ADP-ribose) polymerase (PARP) inhibitors are promising targeted treatment options for hereditary breast tumors with a homologous recombination (HR)…”
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Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series by Simoons, Mirjam, Naipal, Kishan A. T., Jong, Huib, Hoed, Caroline M., Winter, Brenda C. M., Mulder, Midas B.

“…Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can…”
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Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects by Meijer, Titia G, Verkaik, Nicole S, Sieuwerts, Anieta M, van Riet, Job, Naipal, Kishan A T, van Deurzen, Carolien H M, den Bakker, Michael A, Sleddens, Hein F B M, Dubbink, Hendrikus-Jan, den Toom, T Dorine, Dinjens, Winand N M, Lips, Esther, Nederlof, Petra M, Smid, Marcel, van de Werken, Harmen J G, Kanaar, Roland, Martens, John W M, Jager, Agnes, van Gent, Dik C

“…Tumors of germline mutated carriers show homologous recombination (HR) deficiency (HRD), resulting in impaired DNA double-strand break (DSB) repair and high…”
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Ex vivo tumor culture systems for functional drug testing and therapy response prediction by Meijer, Titia G, Naipal, Kishan At, Jager, Agnes, van Gent, Dik C

“…Optimal patient stratification is of utmost importance in the era of personalized medicine. Prediction of individual treatment responses by functional assays…”
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Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma by Blank, Christian U., Lucas, Minke W., Scolyer, Richard A., van de Wiel, Bart A., Menzies, Alexander M., Lopez-Yurda, Marta, Hoeijmakers, Lotte L., Saw, Robyn P.M., Lijnsvelt, Judith M., Maher, Nigel G., Pulleman, Saskia M., Gonzalez, Maria, Torres Acosta, Alejandro, van Houdt, Winan J., Lo, Serigne N., Kuijpers, Anke M.J., Spillane, Andrew, Klop, W. Martin C., Pennington, Thomas E., Zuur, Charlotte L., Shannon, Kerwin F., Seinstra, Beatrijs A., Rawson, Robert V., Haanen, John B.A.G., Ch’ng, Sydney, Naipal, Kishan A.T., Stretch, Jonathan, van Thienen, Johannes V., Rtshiladze, Michael A., Wilgenhof, Sofie, Kapoor, Rony, Meerveld-Eggink, Aafke, Grijpink-Ongering, Lindsay G., van Akkooi, Alexander C.J., Reijers, Irene L.M., Gyorki, David E., Grünhagen, Dirk J., Speetjens, Frank M., Vliek, Sonja B., Placzke, Joanna, Spain, Lavinia, Stassen, Robert C., Amini-Adle, Mona, Lebbé, Céleste, Faries, Mark B., Robert, Caroline, Ascierto, Paolo A., van Rijn, Rozemarijn, van den Berkmortel, Franchette W.P.J., Piersma, Djura, van der Westhuizen, Andre, Vreugdenhil, Gerard, Aarts, Maureen J.B., Stevense-den Boer, Marion A.M., Atkinson, Victoria, Khattak, Muhammad, Andrews, Miles C., van den Eertwegh, Alfons J.M., Boers-Sonderen, Marye J., Hospers, Geke A.P., Carlino, Matteo S., de Groot, Jan-Willem B., Kapiteijn, Ellen, Suijkerbuijk, Karijn P.M., Rutkowski, Piotr, Sandhu, Shahneen, van der Veldt, Astrid A.M., Long, Georgina V.

“…Among patients who received two 3-week cycles of neoadjuvant ipilimumab and nivolumab, the 12-month event-free survival was 83.7%, as compared with 57.2% among…”
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Correction: Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects by Meijer, Titia G, Verkaik, Nicole S, Sieuwerts, Anieta M, van Riet, Job, Naipal, Kishan A T, van Deurzen, Carolien H M, den Bakker, Michael A, Sleddens, Hein F B M, Dubbink, Hendrikus-Jan, den Toom, T Dorine, Dinjens, Winand N M, Lips, Esther, Nederlof, Petra M, Smid, Marcel, van de Werken, Harmen J G, Kanaar, Roland, Martens, John W M, Jager, Agnes, van Gent, Dik C

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Attenuated XPC Expression Is Not Associated with Impaired DNA Repair in Bladder Cancer: e0126029 by Naipal, Kishan AT, Raams, Anja, Bruens, Serena T, Brandsma, Inger, Verkaik, Nicole S, Jaspers, Nicolaas GJ, Hoeijmakers, Jan HJ, Leenders, L Hvan, Pothof, Joris, Kanaar, Roland

“…Bladder cancer has a high incidence with significant morbidity and mortality. Attenuated expression of the DNA damage response protein Xeroderma Pigmentosum…”
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