Search Results - "Nain, Sumitra"
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1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
Published in Frontiers in chemistry (21-01-2022)“…A wide range of biological activities is exhibited by 1,3,4-thiadiazole moiety such as antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral,…”
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2
Antihyperlipidemic Activity of Ethanolic and Aqueous Extracts of Asparagus Racemosus and Chlorophytum Borivilianum Leaves in Albino Rats
Published in National Academy of Sciences, India. Proceedings. Section B. Biological Sciences (01-06-2023)“…Hyperlipidemia is basically a risk factor for causing heart related diseases, strokes, high blood pressure, diabetes, renal disorders, etc. Herbal remedies are…”
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Recent Advances in the Development of Pyrimidine-based CNS Agents
Published in Current drug discovery technologies (01-03-2023)“…In the past few decades, considerable progress has been made in CNS drug discovery, and various new CNS agents have been developed. Pyrimidine is an important…”
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Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold
Published in Chemistry an international journal (01-12-2022)“…The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological…”
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Investigation, scaffold hopping of novel donepezil-based compounds as anti-Alzhiemer’s agents: synthesis, in-silico and pharmacological evaluations
Published in Scientific reports (19-01-2024)“…Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition. The pathogenesis of AD is highly intricate and the disease is apparent in the aged…”
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A Recent Appraisal of Small-Organic Molecules as Anti-Alzheimer's Agents
Published in Mini reviews in medicinal chemistry (01-01-2023)“…Alzheimer's disease (AD) is an irreversible, progressive and very complex brain disorder. There is still uncertainty about the etiology of AD; however, a few…”
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Pyrimidine analogues for the management of neurodegenerative diseases
Published in European journal of medicinal chemistry reports (01-12-2022)“…Neurodegenerative diseases are one of the leading causes of mortality worldwide. Currently available therapeutic agents provide symptomatic relief to a great…”
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Recent Advances in the Synthesis of Xanthines: A Short Review
Published in Scientifica (Cairo) (08-11-2022)“…Xanthine and its derivatives are considered a pharmacologically potential moiety that manifests immense biological activities. Owing to this much diversity in…”
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The memory ameliorating effects of novel N-benzyl pyridine-2-one derivatives on scopolamine-induced cognitive deficits in mice
Published in Laboratory animal research (11-03-2024)“…Alzheimer's disease (AD), the most common form of progressive dementia in the elderly, is a chronic neurological disorder that decreases cognitive ability…”
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Asthma History, Current Situation, an Overview of Its Control History, Challenges, and Ongoing Management Programs: An Updated Review
Published in National Academy of Sciences, India. Proceedings. Section B. Biological Sciences (11-11-2022)“…Asthma is a disease of the airways that is characterized by chronic inflammation and disordered airway function. The purpose of writing the current review…”
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11
Tissue Inhibitor of Metalloproteinase-2 Polymorphisms and Risk for HIV-Associated Neurocognitive Disorder
Published in Mediators of inflammation (01-01-2019)“…The imbalance between MMPs and TIMPs is associated with the HIV dissemination tissue damage pathology neurodegenerative disorders, including HAND. Genetic…”
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Neuroprotective effects of novel pyrrolidine-2-one derivatives on scopolamine-induced cognitive impairment in mice: Behavioral and biochemical analysis
Published in Pharmacology, biochemistry and behavior (01-08-2023)“…Alzheimer's disease (AD) is a long-term neurodegenerative condition that impairs cognitive abilities. In brain acetylcholine deficit and oxidative stress may…”
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An Update on the Green Synthesis of Benzimidazole Scaffolds as Antifungal Agents
Published in Pharmaceutical chemistry journal (01-08-2024)“…The heterocyclic nucleus has a wide range of biological activities with the benzimidazole nucleus having diverse biological activities such as antifungal,…”
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Therapeutic Potential of Pyrazole Containing Compounds: an Updated Review
Published in Pharmaceutical chemistry journal (01-05-2024)“…Among a large number of nitrogen-containing heterocyclic compounds, pyrazole is a privileged scaffold with the molecular formula C 3 H 3 N 2 H. It consists of…”
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Recent Advancements and Biological Activities of Triazole Derivatives: a Short Review
Published in Pharmaceutical chemistry journal (01-03-2024)“…Many heterocyclic triazole rings and compounds containing triazole rings exhibit diverse biological activities. Heterocyclic derivatives of this class possess…”
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Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives
Published in Pharmaceutical chemistry journal (01-05-2023)“…1H-indol-2,3-dione (isatin) class of biologically active compounds have analgesic, anti-microbial, anti-inflammatory, anti-tubercular, anti-proliferative…”
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Synthesis, Characterization and Biological Evaluation of Novel Benzimidazole Derivatives against Candida albicans
Published in Pharmaceutical chemistry journal (01-03-2024)“…In heterocyclic chemistry, benzimidazole is recognized as a “privileged structure” due to its association with a wide range of biological activities. In this…”
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1,3,4-Thiadiazole Scaffold: Anti-Microbial Agents
Published in Pharmaceutical chemistry journal (01-03-2022)“…1,3,4-Thiadiazole moiety has various biological activities including anticancer, antidiabetic, antihypertensive, anti-inflammatory, antiviral, and…”
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Recent Advances in the Biological Significance of Xanthine and its Derivatives: A Review
Published in Pharmaceutical chemistry journal (01-07-2022)“…Xanthine is the most ubiquitous heterocyclic aromatic compound and have attracted much synthetic interest due to their numerous pharmacological activities. It…”
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Synthesis, characterization, and in silico studies of 1,8-naphthyridine derivatives as potential anti-Parkinson's agents
Published in Journal of biomolecular structure & dynamics (11-02-2023)“…1,8-Naphthyridine scaffold is a nitrogen-containing heterocyclic compound known for its versatile biological activities. The structure-activity relationship…”
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