Search Results - "Naim, Mohd Javed"

Recent Advancement in Drug Design and Discovery of Pyrazole Biomolecules as Cancer and Inflammation Therapeutics by Alam, Md Jahangir, Alam, Ozair, Naim, Mohd Javed, Nawaz, Farah, Manaithiya, Ajay, Imran, Mohd, Thabet, Hamdy Khamees, Alshehri, Sultan, Ghoneim, Mohammed M, Alam, Prawez, Shakeel, Faiyaz

“…Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is a five-membered heterocyclic moiety with an extensive therapeutic…”
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Benzimidazole Scaffold as Anticancer Agent: Synthetic Approaches and Structure–Activity Relationship by Shrivastava, Neelima, Naim, Mohd. Javed, Alam, Md. Jahangir, Nawaz, Farah, Ahmed, Shujauddin, Alam, Ozair

“…Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal cell growth having the potential to invade or spread to other parts of…”
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Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole‐based 2,4‐thiazolidinedione derivatives as PPAR‐γ modulators by Naim, Mohd. Javed, Alam, Ozair, Alam, Md. Jahangir, Shaquiquzzaman, Mohammad, Alam, Md. Mumtaz, Naidu, Vegi Ganga Modi

“…The design, synthesis, structure–activity relationship, and biological activity of 2,4‐thiazolidinedione derivatives as peroxisome proliferator‐activated…”
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Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR) by Manaithiya, Ajay, Alam, Ozair, Sharma, Vrinda, Naim, Mohd Javed, Mittal, Shruti, Azam, Faizul, Husain, Asif, Sheikh, Aadil Ahmad, Imran, Mohd, Khan, Imran A

“…Cancer is a heterogeneous disease characterized by an abnormal and uncontrolled division of the cells leading to tumors that invade the adjacent normal…”
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Overview of Chemistry and Therapeutic Potential of Non-Nitrogen Heterocyclics as Anticonvulsant Agents by Pal, Rohit, Singh, Karanvir, Paul, Joyson, Khan, Shah Alam, Naim, Mohd Javed, Akhtar, Md Jawaid

“…Epilepsy is a chronic neurological disorder, characterized by the predisposition of unprovoked seizures affecting the neurobiological, psychological,…”
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Design, synthesis, and molecular docking study of benzothiazolotriazine derivatives for anticonvulsant potential by Firdaus, Jannat Ul, Habib, Anwar, Siddiqui, Nadeem, Alam, Ozair, Naim, Mohd. Javed, Partap, Sangh, Sahu, Meeta

“…A series of newer benzothiazolotriazine derivatives (4a–k) was designed, synthesized, and characterized as anticonvulsant agents against the two classically…”
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Trends in Rationalized Brain Targeted Nanoparticles in Neurological Disorders (Part-III) by Javed, Md Noushad, Ashraf, Ghulam Md, Barreto, George E, Naim, Mohd Javed

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Pyrrole: An insight into recent pharmacological advances with structure activity relationship by Ahmad, Shujauddin, Alam, Ozair, Naim, Mohd. Javed, Shaquiquzzaman, Mohammad, Alam, M. Mumtaz, Iqbal, Muzaffar

“…Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its…”
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Anticonvulsant evaluation of 2-pyrazolines carrying naphthyl moiety: An insight into synthesis and molecular docking study by Nusrat, Birjees, Siddiqui, Nadeem, Sahu, Meeta, Naim, Mohd. Javed, Shahar Yar, Mohammad, Ali, Ruhi, Ozair, Alam

“…A series of N-substituted-3-(napthalen-2-yl)-5-substituted phenyl-4,5-dihydropyrazole-1-carbothioamide derivatives (4a-n) were synthesized with the view of…”
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A review on mushrooms as a versatile therapeutic agent with emphasis on its bioactive constituents for anticancer and antioxidant potential by Naim, Mohd Javed

“…Mushrooms, due to their many medical, preventive, and nutraceutical purposes, as well as their reputation as a folk remedy, have long been an integral part of…”
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Recent advancement in the discovery and development of COX-2 inhibitors: Insight into biological activities and SAR studies (2008–2019) by Sharma, Vrinda, Bhatia, Parth, Alam, Ozair, Javed Naim, Mohd, Nawaz, Farah, Ahmad Sheikh, Aadil, Jha, Mukund

“…[Display omitted] •COX is a family of isozymes responsible for the catalysing reactions of Arachidonic acid.•COX-2 inhibitors based on Pyrazole, Indole,…”
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Therapeutic journey of 2,4-thiazolidinediones as a versatile scaffold: An insight into structure activity relationship by Naim, Mohd. Javed, Alam, Md. Jahangir, Ahmad, Shujauddin, Nawaz, Farah, Shrivastava, Neelima, Sahu, Meeta, Alam, Ozair

“…Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a privileged scaffold in medicinal chemistry; is a derivative of thiazolidine…”
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Lipid-based nanoformulations in the treatment of neurological disorders by Pottoo, Faheem Hyder, Sharma, Shrestha, Javed, Md. Noushad, Barkat, Md. Abul, Harshita, Alam, Md. Sabir, Naim, Mohd. Javed, Alam, Ozair, Ansari, Mohammad Azam, Barreto, George E., Ashraf, Ghulam Md

“…The neurological disorders affect millions of people worldwide, and are bracketed as the foremost basis of disability-adjusted life years (DALYs). The…”
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Current status of pyrazole and its biological activities by Naim, Mohd, Alam, Ozair, Nawaz, Farah, Alam, Md, Alam, Perwaiz

“…Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches…”
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GPR119 agonists: Novel therapeutic agents for type 2 diabetes mellitus by Manaithiya, Ajay, Alam, Ozair, Sharma, Vrinda, Javed Naim, Mohd, Mittal, Shruti, Khan, Imran A

“…[Display omitted] •GPR119 agonist based analogues for treating Diabetes mellitus.•Modifying GPCR activity for modern drug development.•Future perspectives and…”
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Synthesis, molecular docking and anti-diabetic evaluation of 2,4-thiazolidinedione based amide derivatives by Naim, Mohd. Javed, Alam, Md. Jahangir, Nawaz, Farah, Naidu, V.G.M., Aaghaz, Shams, Sahu, Meeta, Siddiqui, Nadeem, Alam, Ozair

“…[Display omitted] •Thiazolidinedione based amide derivatives were evaluated for antidiabetic activity.•Compound 6c appeared as the most potential antidiabetic…”
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Dapagliflozin: A new hope for the therapeutic treatment of type 2 diabetes mellitus by Maksud, Naazneen, Bera, Sidhant, Naim, Mohd Javed, Alam, Ozair

“…Diabetes mellitus (Type 2) is a major world health problem spreading speedily throughout the world. It is a chronic illness that necessitates long-term therapy…”
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An Updated and Focused Review on Heterocyclic Inhibitors for SARSCoV and SARS-CoV-2 3CL pro by Manaithiya, Ajay, Alam, Ozair, Mittal, Shruti, Naim, Mohd Javed, Imran, Mohd, Alshrari, Ahmed Subeh, Sheikh, Aadil A, Khan, Imran A

“…SARS-CoV and SARS-CoV-2 are exceedingly contagious and typically result in major respiratory illnesses (acute respiratory syndrome). The public health is…”
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Recent advancement in the discovery and development of anti-epileptic biomolecules: An insight into structure activity relationship and Docking by Jha, Mukund, Alam, Ozair, Naim, Mohd. Javed, Sharma, Vrinda, Bhatia, Parth, Sheikh, Aadil Ahmad, Nawaz, Farah, Alam, Perwaiz, Manaithiya, Ajay, Kumar, Vivek, Nazar, Shagufi, Siddiqui, Nadeem

“…•Convulsion is a neurological condition triggered by recurring unprovoked seizure that may upset physical, mental and behavioural operations.•SAR and docking…”
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Design, Synthesis, and Docking Study of Pyrimidine–Triazine Hybrids for GABA Estimation in Animal Epilepsy Models by Sahu, Meeta, Siddiqui, Nadeem, Naim, Mohd. Javed, Alam, Ozair, Yar, Mohammad Shahar, Sharma, Vidushi, Wakode, Sharad

“…A series of new pyrimidine–triazine hybrids (4a–t) was designed and synthesized, from which potent anticonvulsant agents were identified. Most of the compounds…”
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