Search Results - "Naidoo, Kogieleum"

Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care by Dookie, Navisha, Rambaran, Santhuri, Padayatchi, Nesri, Mahomed, Sharana, Naidoo, Kogieleum

“…Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and control programmes worldwide. Advances in sequencing technology have…”
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Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection by Drain, Paul K, Bajema, Kristina L, Dowdy, David, Dheda, Keertan, Naidoo, Kogieleum, Schumacher, Samuel G, Ma, Shuyi, Meermeier, Erin, Lewinsohn, David M, Sherman, David R

“…Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a limited understanding of its clinical pathogenic spectrum of…”
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Application of Next Generation Sequencing for Diagnosis and Clinical Management of Drug-Resistant Tuberculosis: Updates on Recent Developments in the Field by Dookie, Navisha, Khan, Azraa, Padayatchi, Nesri, Naidoo, Kogieleum

“…The World Health Organization's End TB Strategy prioritizes universal access to an early diagnosis and comprehensive drug susceptibility testing (DST) for all…”
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Metformin as Host-Directed Therapy for TB Treatment: Scoping Review by Naicker, Nikita, Sigal, Alex, Naidoo, Kogieleum

“…Tuberculosis (TB) disease is an international health concern caused by the bacteria . Evolution of multi-drug-resistant strains may cause bacterial…”
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Long-term adherence to antiretroviral therapy in a South African adult patient cohort: a retrospective study by Moosa, Atika, Gengiah, Tanuja N, Lewis, Lara, Naidoo, Kogieleum

“…South Africa has the highest HIV prevalence and supports the largest antiretroviral therapy (ART) programme globally. With the introduction of a test and treat…”
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Integration of Antiretroviral Therapy with Tuberculosis Treatment by Abdool Karim, Quarraisha, Abdool Karim, Salim S, Naidoo, Kogieleum, Naidoo, Anushka, Grobler, Anneke, Padayatchi, Nesri, Baxter, Cheryl, Gray, Andrew L, Gengiah, Tanuja, Gengiah, Santhanalakshmi, Jithoo, Niraksha, Nair, Gonasagrie, El-Sadr, Wafaa M, Friedland, Gerald

“…In this study from South Africa, earlier initiation of antiretroviral therapy in patients with newly diagnosed HIV infection and TB was associated with higher…”
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Incidence and prevalence of hypertension among HIV-TB co-infected participants accessing treatment: A five-year prospective cohort analysis by Dawood, Halima, Yende-Zuma, Nonhlanhla, Singh, Upasna, Moodley, Mikaila C, Ramruthan, Jenine, Naidoo, Kogieleum

“…Hypertension is a leading risk factor for cardiovascular disease among people living with human immunodeficiency virus (PLWH). This study determined incidence…”
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TB epidemiology: where are the young women? Know your tuberculosis epidemic, know your response by Perumal, Rubeshan, Naidoo, Kogieleum, Padayatchi, Nesri

“…The global predominance of tuberculosis in men has received significant attention. However, epidemiological studies now demonstrate that there is an increased…”
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Mortality and treatment response amongst HIV-infected patients 50 years and older accessing antiretroviral services in South Africa by Dawood, Halima, Hassan-Moosa, Razia, Zuma, Nonhlanhla-Yende, Naidoo, Kogieleum

“…Little is known about the clinical presentation and outcomes amongst older HIV infected populations accessing ART in sub-Saharan Africa. We compared mortality…”
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Brief Report: Differentiated Service Delivery Framework for People With Multidrug-Resistant Tuberculosis and HIV Coinfection by Reis, Karl, Wolf, Allison, Perumal, Rubeshan, Seepamore, Boitumelo, Guzman, Kevin, Ross, Jesse, Cheung, Ying Kuen K., Amico, K. Rivet, Brust, James C. M., Padayatchi, Nesri, Friedland, Gerald, Naidoo, Kogieleum, Daftary, Amrita, Zelnick, Jennifer, O'Donnell, Max

“…Introduction: For people living with HIV/AIDS, care is commonly delivered through differentiated service delivery (DSD). Although people with…”
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Long COVID: An approach to clinical assessment and management in primary care by Perumal, Rubeshan, Shunmugam, Letitia, Naidoo, Kogieleum

“…Long COVID is an emerging public health threat, following swiftly behind the surges of acute infection over the course of the COVID-19 pandemic. It is…”
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Long COVID: a review and proposed visualization of the complexity of long COVID by Perumal, Rubeshan, Shunmugam, Letitia, Naidoo, Kogieleum, Abdool Karim, Salim S, Wilkins, Dave, Garzino-Demo, Alfredo, Brechot, Christian, Parthasarathy, Sairam, Vahlne, Anders, Nikolich, Janko Ž

“…Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus - 2 (SARS-CoV-2) infection, or Long COVID, is a prevailing second pandemic with nearly 100…”
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Bedaquiline Adherence Measured by Electronic Dose Monitoring Predicts Clinical Outcomes in the Treatment of Patients With Multidrug-Resistant Tuberculosis and HIV/AIDS by O'Donnell, Max R., Padayatchi, Nesri, Wolf, Allison, Zelnick, Jennifer, Daftary, Amrita, Orrell, Catherine, Nimmo, Camus, Baldwin, Matthew, Boodhram, Resha, Maharaj, Bhavna, Amico, K. Rivet, Naidoo, Kogieleum, Friedland, Gerald

“…Novel regimens have revolutionized multidrug-resistant tuberculosis (MDR-TB) treatment; however, medication adherence remains challenging and poorly…”
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A retrospective cohort study of body mass index and survival in HIV infected patients with and without TB co-infection by Naidoo, Kogieleum, Yende-Zuma, Nonhlanhla, Augustine, Stanton

“…High early morbidity and mortality following antiretroviral therapy (ART) initiation has been a distinguishing feature of ART programmes in resource limited…”
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Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings by Manyana, Sontaga, Pillay, Melendhran, Gounder, Lilishia, Khan, Aabida, Moodley, Pravi, Naidoo, Kogieleum, Chimukangara, Benjamin

“…As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable…”
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HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies by Manyana, Sontaga, Gounder, Lilishia, Pillay, Melendhran, Manasa, Justen, Naidoo, Kogieleum, Chimukangara, Benjamin

“…Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral treatment (ART) success with the goal of eradicating HIV-1 infection…”
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NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity by Maseko, Thando Glory, Rambaran, Santhuri, Ngubane, Slindile, Lewis, Lara, Ngcapu, Sinaye, Hassan-Moosa, Razia, Archary, Derseree, Perumal, Rubeshan, Padayatchi, Nesri, Naidoo, Kogieleum, Sivro, Aida

“…Natural killer (NK) cells, key effector cells of the innate immune system, play an important role in the clearance and control of Mycobacterium tuberculosis…”
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Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research by Dorward, Jienchi, Lessells, Richard, Drain, Paul K, Naidoo, Kogieleum, de Oliveira, Tulio, Pillay, Yogan, Abdool Karim, Salim S, Garrett, Nigel

“…A new first-line antiretroviral therapy (ART) regimen containing dolutegravir is being rolled out in low-income and middle-income countries (LMICs). In studies…”
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Discordant line probe genotypic testing vs culture-based drug susceptibility phenotypic testing in TB endemic KwaZulu-Natal: Impact on bedside clinical decision making by Mahomed, Sharana, Mlisana, Koleka, Cele, Lindiwe, Naidoo, Kogieleum

“…The recommendations for Mycobacterium tuberculosis drug susceptibility testing include both phenotypic and genotypic methods. This concurrent use of differing…”
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Joint modelling of longitudinal and time-to-event data: an illustration using CD4 count and mortality in a cohort of patients initiated on antiretroviral therapy by Mchunu, Nobuhle N, Mwambi, Henry G, Reddy, Tarylee, Yende-Zuma, Nonhlanhla, Naidoo, Kogieleum

“…Modelling of longitudinal biomarkers and time-to-event data are important to monitor disease progression. However, these two variables are traditionally…”
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