Search Results - "Nahon, Kimberly J"

The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults by Martinez-Tellez, Borja, Nahon, Kimberly J., Sanchez-Delgado, Guillermo, Abreu-Vieira, Gustavo, Llamas-Elvira, Jose M., van Velden, Floris H. P., Pereira Arias-Bouda, Lenka M., Rensen, Patrick C. N., Boon, Mariëtte R., Ruiz, Jonatan R.

“…Human brown adipose tissue (BAT) is commonly assessed by cold-induced 18 F-fluorodeoxyglucose (FDG) PET-CT using several quantification criteria. Uniform…”
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High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue by Kuipers, Eline N, Kantae, Vasudev, Maarse, Boukje C Eveleens, van den Berg, Susan M, van Eenige, Robin, Nahon, Kimberly J, Reifel-Miller, Anne, Coskun, Tamer, de Winther, Menno P J, Lutgens, Esther, Kooijman, Sander, Harms, Amy C, Hankemeier, Thomas, van der Stelt, Mario, Rensen, Patrick C N, Boon, Mariëtte R

“…The endocannabinoid system (ECS) controls energy balance by regulating both energy intake and energy expenditure. Endocannabinoid levels are elevated in…”
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Salsalate activates brown adipose tissue in mice by van Dam, Andrea D, Nahon, Kimberly J, Kooijman, Sander, van den Berg, Susan M, Kanhai, Anish A, Kikuchi, Takuya, Heemskerk, Mattijs M, van Harmelen, Vanessa, Lombès, Marc, van den Hoek, Anita M, de Winther, Menno P J, Lutgens, Esther, Guigas, Bruno, Rensen, Patrick C N, Boon, Mariëtte R

“…Salsalate improves glucose intolerance and dyslipidemia in type 2 diabetes patients, but the mechanism is still unknown. The aim of the current study was to…”
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Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men by Kantae, Vasudev, Nahon, Kimberly J., Straat, Maaike E., Bakker, Leontine E. H., Harms, Amy C., van der Stelt, Mario, Hankemeier, Thomas, Jazet, Ingrid M., Boon, Mariëtte R., Rensen, Patrick C. N.

“…South Asians have a higher risk to develop obesity and related disorders compared to white Caucasians. This is likely in part due to their lower resting energy…”
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Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers by Abreu-Vieira, Gustavo, Sardjoe Mishre, Aashley S D, Burakiewicz, Jedrzej, Janssen, Laura G M, Nahon, Kimberly J, van der Eijk, Jari A, Riem, Titia T, Boon, Mariëtte R, Dzyubachyk, Oleh, Webb, Andrew G, Rensen, Patrick C N, Kan, Hermien E

“…Magnetic resonance imaging (MRI) is increasingly being used to evaluate brown adipose tissue (BAT) function. Reports on the extent and direction of…”
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Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans by Hoeke, Geerte, Nahon, Kimberly J, Bakker, Leontine E.H, Norkauer, Sabine S.C, Dinnes, Donna L.M, Kockx, Maaike, Lichtenstein, Laeticia, Drettwan, Diana, Reifel-Miller, Anne, Coskun, Tamer, Pagel, Philipp, Romijn, Fred P.H.T.M, Cobbaert, Christa M, Jazet, Ingrid M, Martinez, Laurent O, Kritharides, Leonard, Berbée, Jimmy F.P, Boon, Mariëtte R, Rensen, Patrick C.N

“…Background Cold exposure and β3-adrenergic receptor agonism, which both activate brown adipose tissue, markedly influence lipoprotein metabolism by enhancing…”
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Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men by Janssen, Laura G M, Van Dam, Andrea D, Hanssen, Mark J W, Kooijman, Sander, Nahon, Kimberly J, Reinders, Hanneke, Jazet, Ingrid M, Van Marken Lichtenbelt, Wouter D, Rensen, Patrick C N, Appelman-Dijkstra, Natasha M, Boon, Mariëtte R

“…South Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt…”
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Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males by Janssen, Laura G.M., Nahon, Kimberly J., Bracké, Katrien F.M., van den Broek, Dennis, Smit, Renée, Sardjoe Mishre, Aashley S.D., Koorneef, Lisa L., Martinez-Tellez, Borja, Burakiewicz, Jedrzej, Kan, Hermien E., van Velden, Floris H.P., Pereira Arias-Bouda, Lenka M., de Geus-Oei, Lioe-Fee, Berbée, Jimmy F.P., Jazet, Ingrid M., Boon, Mariëtte R., Rensen, Patrick C.N.

“…Brown adipose tissue (BAT) improves energy metabolism by combusting glucose and lipids into heat. Agonism of the glucagon-like peptide-1 receptor (GLP-1R)…”
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Effect of l-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study by Boon, Mariëtte R., Hanssen, Mark J. W., Brans, Boudewijn, Hülsman, Cindy J. M., Hoeks, Joris, Nahon, Kimberly J., Bakker, Charlotte, van Klinken, Jan B., Havekes, Bas, Schaart, Gert, Jazet, Ingrid M., Rensen, Patrick C. N., van Marken Lichtenbelt, Wouter D.

“…Aims/hypothesis Individuals of South Asian origin are at increased risk of developing type 2 diabetes mellitus and associated comorbidities compared with…”
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The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men by Nahon, Kimberly J., Janssen, Laura G. M., Sardjoe Mishre, Aashley S. D., Bilsen, Manu P., Eijk, Jari A., Botani, Kani, Overduin, Lisanne A., Ruiz, Jonatan R., Burakiewicz, Jedrzej, Dzyubachyk, Oleh, Webb, Andrew G., Kan, Hermien E., Berbée, Jimmy F. P., Klinken, Jan‐Bert, Dijk, Ko Willems, Weeghel, Michel, Vaz, Frédéric M., Coskun, Tamer, Jazet, Ingrid M., Kooijman, Sander, Martinez‐Tellez, Borja, Boon, Mariëtte R., Rensen, Patrick C. N.

“…Aim To compare the effects of cold exposure and the β3‐adrenergic receptor agonist mirabegron on plasma lipids, energy expenditure and brown adipose tissue…”
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Comprehensive (apo)lipoprotein profiling in patients with genetic hypertriglyceridemia using LC-MS and NMR spectroscopy by Straat, Maaike E., Martinez-Tellez, Borja, Nahon, Kimberly J., Janssen, Laura G.M., Verhoeven, Aswin, van der Zee, Leonie, Mulder, Monique T., Kooijman, Sander, Boon, Mariëtte R., van Lennep, Jeanine E. Roeters, Cobbaert, Christa M., Giera, Martin, Rensen, Patrick C.N.

“…•Mutations in LPL or its regulators can cause genetic hypertriglyceridemia (HTG)•Multiplex LC-MS and NMR spectroscopy provide detailed (apo)lipoprotein…”
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Effect of sitagliptin on energy metabolism and brown adipose tissue in overweight individuals with prediabetes: a randomised placebo-controlled trial by Nahon, Kimberly J., Doornink, Fleur, Straat, Maaike E., Botani, Kani, Martinez-Tellez, Borja, Abreu-Vieira, Gustavo, van Klinken, Jan B., Voortman, Gardi J., Friesema, Edith C. H., Ruiz, Jonatan R., van Velden, Floris H. P., de Geus-Oei, Lioe-Fee, Smit, Frits, Pereira Arias-Bouda, Lenka M., Berbée, Jimmy F. P., Jazet, Ingrid M., Boon, Mariëtte R., Rensen, Patrick C. N.

“…Aims/hypothesis The aim of this study was to evaluate the effect of sitagliptin on glucose tolerance, plasma lipids, energy expenditure and metabolism of brown…”
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Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial by Straat, Maaike E., Jurado-Fasoli, Lucas, Ying, Zhixiong, Nahon, Kimberly J., Janssen, Laura G.M., Boon, Mariëtte R., Grabner, Gernot F., Kooijman, Sander, Zimmermann, Robert, Giera, Martin, Rensen, Patrick C.N., Martinez-Tellez, Borja

“…The application of cold exposure has emerged as an approach to enhance whole-body lipid catabolism. The global effect of cold exposure on the lipidome in…”
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Gene Expression of Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight by Nahon, Kimberly J., Kantae, Vasudev, Haan, Roy, Hanssen, Mark J.W., Harms, Amy C., Stelt, Mario, Hankemeier, Thomas, Jazet, Ingrid M., Marken Lichtenbelt, Wouter D., Rensen, Patrick C.N., Boon, Mariëtte R.

“…Objective The study aimed to investigate whether markers of endocannabinoid signaling differed between men with overweight of South Asian and white Caucasian…”
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LDL aggregation susceptibility is higher in healthy South Asian compared with white Caucasian men by Ruuth, Maija, Janssen, Laura G.M., Äikäs, Lauri, Tigistu-Sahle, Feven, Nahon, Kimberly J., Ritvos, Olli, Ruhanen, Hanna, Käkelä, Reijo, Boon, Mariëtte R., Öörni, Katariina, Rensen, Patrick C.N.

“…South Asians are more prone to develop atherosclerotic cardiovascular disease (ASCVD) compared with white Caucasians, which is not fully explained by classical…”
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Lower critical temperature and cold-induced thermogenesis of lean and overweight humans are inversely related to body mass and basal metabolic rate by Nahon, Kimberly J., Boon, Mariëtte R., Doornink, Fleur, Jazet, Ingrid M., Rensen, Patrick C.N., Abreu-Vieira, Gustavo

“…It is colloquially stated that body size plays a role in the human response to cold, but the magnitude and details of this interaction are unclear. To explore…”
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Physiological changes due to mild cooling in healthy lean males of white Caucasian and South Asian descent: A metabolomics study by Nahon, Kimberly J., Boon, Mariëtte R., Bakker, Leontine E.H., Prehn, Cornelia, Adamski, Jerzy, Jazet, Ingrid M., van Dijk, Ko Willems, Rensen, Patrick C.N., Mook-Kanamori, Dennis O.

“…During mild cold exposure, non-shivering thermogenesis increases to maintain core body temperature by increasing utilization of substrates, especially fatty…”
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Short-term cooling increases serum angiopoietin-like 4 levels in healthy lean men by Nahon, Kimberly J., Hoeke, Geerte, Bakker, Leontine E.H., Jazet, Ingrid M., Berbée, Jimmy F.P., Kersten, Sander, Rensen, Patrick C.N., Boon, Mariëtte R.

“…Cold exposure enhances sympathetic outflow to peripheral tissues, thereby stimulating intracellular lipolysis in white adipose tissue and increasing the…”
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Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes by Janssen, Laura G M, Jauhiainen, Matti, Olkkonen, Vesa M, Haridas, P A Nidhina, Nahon, Kimberly J, Rensen, Patrick C N, Boon, Mariëtte R

“…Angiopoietin-like proteins (ANGPTLs) regulate triglyceride (TG)-rich lipoprotein distribution via inhibiting TG hydrolysis by lipoprotein lipase in metabolic…”
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Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol‐intoxicated volunteers by te Beek, Erik T., Hay, Justin L., Bullman, Jonathan N., Burgess, Clare, Nahon, Kimberly J., Klaassen, Erica S., Gray, Frank A., Gerven, Joop M. A.

“…Aims Antagonism of both NK1 and NK3 receptors may be an effective strategy in the pharmacotherapy of schizophrenia, drug addiction or depression. GSK1144814 is…”
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