Search Results - "Nagy, Botond"
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Alterations in erythrocyte membrane transporter expression levels in type 2 diabetic patients
Published in Scientific reports (02-02-2021)“…Type 2 diabetes mellitus (T2DM) is one of the most common multifactorial diseases and several membrane transporters are involved in its development,…”
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2
Potential role of the ABCG2-Q141K polymorphism in type 2 diabetes
Published in PloS one (02-12-2021)“…Type 2 diabetes mellitus (T2DM) is a complex metabolic disease and variations in multispecific membrane transporter functions may affect T2DM development,…”
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3
Genetic Modulation of the GLUT1 Transporter Expression—Potential Relevance in Complex Diseases
Published in Biology (Basel, Switzerland) (16-11-2022)“…The human GLUT1 (SLC2A1) membrane protein is the key glucose transporter in numerous cell types, including red cells, kidney, and blood-brain barrier cells…”
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4
Altered gene expressions in periferal blood cells of first-degree non-diabetic relatives of type 2 diabetic patients
Published in Orvosi hetilap (01-05-2020)“…Introduction and aim: We were looking for altered gene expression on peripheral blood cells significant to type 2 diabetes causing the world epidemic. Method:…”
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5
Thermodynamic Bethe Ansatz and generalised hydrodynamics in the sine-Gordon model
Published in SciPost physics (01-06-2024)“…We set up a hydrodynamic description of the non-equilibrium dynamics of sine-Gordon quantum field theory for generic coupling. It is built upon an explicit…”
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6
Improvement of insulin sensitivity by a novel drug candidate, BGP-15, in different animal studies
Published in Metabolic syndrome and related disorders (01-03-2014)“…Insulin resistance has been recognized as the most significant predictor of further development of type 2 diabetes mellitus (T2DM). Here we investigated the…”
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7
Improving Performance Capable Knowledge in Youth Basketball by Applying with Targeted Shooting Program
Published in Studia Universitatis Babeș-Bolyai. Educatio artis gymnasticae (30-09-2018)“…Today’s basketball player profile can be divided to four resources: physical, mental, spiritual and emotional (Woods, Jordan, 2010). Our research supervised…”
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8
The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics
Published in Cell stress & chaperones (01-07-2012)“…Weight gain and dysfunction of glucose and lipid metabolism are well-known side effects of atypical antipsychotic drugs (AAPD). Here, we address the question…”
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9
Useful Tools to Predict Future Performance? Analysis of Former Individually Prized Young Selected Male Basketball Players
Published in Studia Universitatis Babeș-Bolyai. Educatio artis gymnasticae (01-09-2021)“…"Success in team sports foremostly depends on individual performance and the cooperation of the team members. We aimed to investigate the individual…”
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10
Synergetic Insulin Sensitizing Effect of Rimonabant and BGP-15 in Zucker-Obes Rats
Published in Pathology oncology research (01-07-2013)“…Abdominal obesity is referred for as a common pathogenic root of multiple risk factors, which include insulin resistance, dyslipidemia, hypertension, and a…”
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A Novel Insulin Sensitizer Drug Candidate—BGP-15—Can Prevent Metabolic Side Effects of Atypical Antipsychotics
Published in Pathology oncology research (01-10-2012)“…Atypical antipsychotic drugs (AAPD) are widely used to treat severe psychiatric disorders, have well documented metabolic side effects such as disturbances in…”
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12
Metabolic differences in healthy first-degree female relatives of type 2 diabetic patients
Published in Orvosi hetilap (03-11-2013)“…Today the prevalence of type 2 diabetes reached an epidemic level. It is known that type 2 diabetes could only be prevented before the manifestation, during…”
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13
Metabolic alteration in healthy men with first degree type 2 diabetic relatives
Published in Orvosi hetilap (03-02-2013)“…The recognition of prediabetic patients with the genetic risk of type 2 diabetes is very important as prediabetes is the last stage when manifestation of…”
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14
The production of l- and d-phenylalanines using engineered phenylalanine ammonia lyases from Petroselinum crispum
Published in Scientific reports (27-12-2019)“…The biocatalytic synthesis of l - and d -phenylalanine analogues of high synthetic value have been developed using as biocatalysts mutant variants of…”
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15
Serum osteocalcin is associated with improved metabolic state via adiponectin in females versus testosterone in males. Gender specific nature of the bone–energy homeostasis axis
Published in Bone (New York, N.Y.) (01-11-2013)“…Abstract Objective The osteoblast-derived protein osteocalcin (OCN) is known to be involved in glucose metabolism by increasing adiponectin secretion from…”
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Covalently Immobilized Lipases are Efficient Stereoselective Catalysts for the Kinetic Resolution of rac-(5-Phenylfuran-2-yl)-[beta]-alanine Ethyl Ester Hydrochlorides
Published in European journal of organic chemistry (01-05-2017)“…Lipase-catalyzed enzymatic resolution of several new, exotic and variously substituted rac-(5-phenylfuran-2-yl)-[beta]-alanine ethyl esters was investigated…”
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Covalently Immobilized Lipases are Efficient Stereoselective Catalysts for the Kinetic Resolution of rac‐(5‐Phenylfuran‐2‐yl)‐β‐alanine Ethyl Ester Hydrochlorides
Published in European journal of organic chemistry (26-05-2017)“…Lipase‐catalyzed enzymatic resolution of several new, exotic and variously substituted rac‐(5‐phenylfuran‐2‐yl)‐β‐alanine ethyl esters was investigated. Given…”
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18
Sex influenced association of directly measured insulin sensitivity and serum transaminase levels: Why alanine aminotransferase only predicts cardiovascular risk in men?
Published in Cardiovascular diabetology (20-05-2015)“…Non alcoholic fatty liver disease (NAFLD) is an independent cardiovascular (CV) risk factor which is closely associated with insulin resistance measured by…”
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Microfluidic Multiple Cell Chip Reactor Filled with Enzyme-Coated Magnetic Nanoparticles — An Efficient and Flexible Novel Tool for Enzyme Catalyzed Biotransformations
Published in Journal of flow chemistry (01-03-2016)“…Biotransformation of L-phenylalanine (L- 1a ) and five unnatural substrates ( rac - 1b–f ) by phenylalanine ammonia-lyase (PAL) was investigated in a novel…”
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20
New chemo-enzymatic approaches for the synthesis of (R)- and (S)-bufuralol
Published in Tetrahedron: asymmetry (15-10-2014)“…Both enantiomers of bufuralol are pharmaceutically important molecules. While the (S)-isomer with a higher β-blocking activity is recommended for hypertension…”
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