Search Results - "Nagy, Becky"

Abstract 401: Comparison of molecular response calculations for prediction of patient outcome by Mak, Allysia J., Quinn, Katie J., Espenschied, Carin, Chang, Kyle, Chuang, Han-Yu, Helman, Elena, Chudova, Darya, Odegaard, Justin, Nagy, Becky, Talasaz, AmirAli

“…Abstract Background: Molecular response (MR) estimated as a change in circulating tumor (ctDNA) load between an early on treatment sample (usually 2-9 weeks…”
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Abstract PD9-07: Genomic landscape of metastatic breast cancer (MBC): Comprehensive cell-free DNA analysis from over 10,000 patients and comparison with primary breast cancer by Bardia, Aditya, Cristofanilli, Massimo, Cha, Justin, Kiedrowski, Lesli, Juric, Dejan, Park, Ben H, Brufsky, Adam, O’Shaughnessy, Joyce, Nagy, Becky, Ellisen, Leif, Leshchiner, Ignaty, Getz, Gaddy

“…Abstract Background: Current tissue-based genomic sequencing datasets typically reflect early stage, mostly treatment-naïve cohorts, and fail to capture the…”
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Abstract P5-13-29: Analytical and clinical validation of a ctDNA assay for detecting copy number loss and structural rearrangement variants contributing to homologous recombination and repair (HRR) deficiency by Yen, Jennifer, Drusbosky, Leylah, Weipert, Caroline, Zhang, Nicole, Hanna, David, Barbacioru, Catalin, Wang, Hao, Artyomenko, Alex, Yablonovitch, Arielle, Fu, Yu, Hardin, Aaron, Alla, Nagesh, Foley, Robert, Maligska, Max, Panchangam, Bhargavi, Yen, Phil, Meisel, Jane, Vidula, Neelima, Cristofanilli, Massimo, Force, Jeremy, Dorschner, Michael, Lefterova, Martina, Helman, Elena, Nagy, Becky, Chudova, Darya, Talasaz, AmirAli

“…Abstract Background: Inactivating HRR gene mutations can lead to HRR deficiency (HRD) and predict response to PARPi therapy in patients with breast cancer…”
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Abstract 729: Landscape of homologous recombination repair (HRR) mutations in prostate cancer profiled by ctDNA next-generation sequencing by Yen, Jennifer, Gnerre, Sante, Barbacioru, Catalin, Helman, Elena, Manor, Ohad, Yablonovitch, Arielle, Satya, Ravi Vijaya, Liu, Leo, Saam, Jennifer, Fairclough, Stephen, Nagy, Becky, Lanman, Richard, Chudova, Darya, Talasaz, AmirAli

“…Abstract Background: PARP inhibition can cause synthetic lethality and increased therapeutic sensitivity in patients with HRR deficiency (HRD), which can be…”
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Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer by Vidula, Neelima, Dubash, Taronish, Lawrence, Michael S, Simoneau, Antoine, Niemierko, Andrzej, Blouch, Erica, Nagy, Becky, Roh, Whijae, Chirn, Brian, Reeves, Brittany A, Malvarosa, Giuliana, Lennerz, Jochen, Isakoff, Steven J, Juric, Dejan, Micalizzi, Douglas, Wander, Seth, Spring, Laura, Moy, Beverly, Shannon, Kristen, Younger, Jerry, Lanman, Richard, Toner, Mehmet, Iafrate, A John, Getz, Gad, Zou, Lee, Ellisen, Leif W, Maheswaran, Shyamala, Haber, Daniel A, Bardia, Aditya

“…Plasma genotyping may identify mutations in potentially "actionable" cancer genes, such as , but their clinical significance is not well-defined. We evaluated…”
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Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cance by Vidula, Neelima, Dubash, Taronish, Lawrence, Michael S., Simoneau, Antoine, Niemierko, Andrzej, Blouch, Erica, Nagy, Becky, Roh, Whijae, Chirn, Brian, Reeves, Brittany A., Malvarosa, Giuliana, Lennerz, Jochen, Isakoff, Steven J., Juric, Dejan, Micalizzi, Douglas, Wander, Seth, Spring, Laura, Moy, Beverly, Shannon, Kristen, Younger, Jerry, Lanman, Richard, Toner, Mehmet, Iafrate, A. John, Getz, Gad, Zou, Lee, Ellisen, Leif W., Maheswaran, Shyamala, Haber, Daniel A., Bardia, Aditya

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Abstract A183: Blood-based genomic profiling of cell-free tumor DNA (ctDNA) in patients with biliary tract cancer by Goyal, Lipika, Kate Kelley, Robin, Kiedrowski, Lesli, Catenacci, Daniel, Mody, Kabir, Shroff, Rachna, Parikh, Aparna, Reyes, Stephanie, Maurer, Jordan R., Corcoran, Ryan B., Fanta, Paul, Cusnir, Mike, Nagy, Becky, Lanman, Richard, Morse, Michael, Tan, Benjamin, Javle, Milind, Zhu, Andrew

“…Abstract Background: Targeted therapies are increasingly under evaluation in clinical trials for the treatment of biliary tract cancer (BTC), and cell-free…”
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Abstract 4343: Comparison of over 10,000 clinical NGS circulating tumor DNA profiles to tissue-derived genomic compendia by Zill, Oliver A., Banks, Kimberly C., Jackson, Coyt, Mortimer, Stefanie, Baca, Arthur, Nagy, Becky, Lanman, Richard B., Eltoukhy, Helmy, Talasaz, AmirAli

“…Abstract Analysis of cell-free circulating tumor DNA (ctDNA) enables non-invasive and serially repeatable genomic profiling of advanced cancer patients,…”
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