Search Results - "Naguib, Marianne J."

Scalable flibanserin nanocrystal-based novel sublingual platform for female hypoactive sexual desire disorder: engineering, optimization adopting the desirability function approach and in vivo pharmacokinetic study by Naguib, Marianne J., Makhlouf, Amal I. A.

“…Flibanserin (FLB) was approved by FDA for the treatment of pre-menopausal female hypoactive sexual desire disorder (HSDD). FLB suffers from low oral…”
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Compritol-Based Nanostrucutured Lipid Carriers (NLCs) for Augmentation of Zolmitriptan Bioavailability via the Transdermal Route: In Vitro Optimization, Ex Vivo Permeation, In Vivo Pharmacokinetic Study by Hassan, Doaa H., Shohdy, Joseph N., El-Setouhy, Doaa Ahmed, El-Nabarawi, Mohamed, Naguib, Marianne J.

“…Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing headaches. Triptans are agonists for serotonin receptors. Zolmitriptan…”
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Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity &in vivo biodistribution utilizing radioiodinated zopiclone by Taha, Esraa, Nour, Samia A., Mamdouh, Wael, Selim, Adli A., Swidan, Mohamed M., Ibrahim, Ahmed B., Naguib, Marianne J.

“…Nano-structured lipid carriers containing zopiclone were prepared as a targeted drug delivery system to convey zopiclone directly to brain via nasal route…”
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Spanlastics as a Potential Platform for Enhancing the Brain Delivery of Flibanserin: In Vitro Response-Surface Optimization and In Vivo Pharmacokinetics Assessment by Alharbi, Waleed S, Hareeri, Rawan H, Bazuhair, Mohammed, Alfaleh, Mohamed A, Alhakamy, Nabil A, Fahmy, Usama A, Alamoudi, Abdullah A, Badr-Eldin, Shaimaa M, Ahmed, Osama A, AlGhamdi, Shareefa A, Naguib, Marianne J

“…Flibanserin was licensed by the United States Food and Drug Administration (FDA) as an oral non-hormonal therapy for pre-menopausal women with inhibited sexual…”
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Investigating the potential of highly porous zopiclone-loaded 3D electrospun nanofibers for brain targeting via the intranasal route by Taha, Esraa, Nour, Samia A., Mamdouh, Wael, Naguib, Marianne J.

“…[Display omitted] •Zopiclone-loaded 3D nanofibers were fabricated by using electrospinning.•Prepared NFs showed excellent mechanical properties, swelling…”
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3D printed ocusert laden with ultra-fluidic glycerosomes of ganciclovir for the management of ocular cytomegalovirus retinitis by Naguib, Marianne J., Hassan, Youssef R., Abd-Elsalam, Wessam H.

“…[Display omitted] Cytomegalovirus (CMV) retinitisis a vision-threatening disease that principally afflicts immunosuppressed patients. For the management of the…”
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Investigating the potential of utilizing glycerosomes as a novel vesicular platform for enhancing intranasal delivery of lacidipine by Naguib, Marianne J., Salah, Salwa, Abdel Halim, Sally A., Badr-Eldin, Shaimaa M.

“…[Display omitted] Lacidipine is a potent dihydropyridine calcium channel blocker used for management of hypertension and atherosclerosis. The drug has low and…”
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Versatile Nanoparticulate Systems as a Prosperous Platform for Targeted Nose–Brain Drug Delivery by Taha, Esraa, Shetta, Amro, Nour, Samia A., Naguib, Marianne J., Mamdouh, Wael

“…The intranasal route has proven to be a reliable and promising route for delivering therapeutics to the central nervous system (CNS), averting the blood–brain…”
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Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo biodistribution and pharmacodynamics studies by Nour, Samia A, Abdelmalak, Nevine S, Naguib, Marianne J, Rashed, Hassan M, Ibrahim, Ahmed B

“…Clonazepam (CZ) is an anti-epileptic drug used mainly in status epilepticus (SE). The drug belongs to Class II according to BCS classification with very…”
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Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: in-vitro optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation by Aziz, Sandy N., Badawy, Alia A., Nessem, Demiana I., Abd El Malak, Nevine S., Naguib, Marianne J.

“…The aim of the present study was to formulate chitosan-coated alginate nanoparticles containing the drug diphenhydramine hydrochloride (DHH). Diphenhydramine…”
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Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation in rabbits by Nour, Samia A, Abdelmalak, Nevine Shawky, Naguib, Marianne J

“…The objective of this study was the development of a colon-targeted microspheres which were compressed into tablets containing the non-steroidal…”
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Optimization and evaluation of chitosan buccal films containing tenoxicam for treating chronic periodontitis: In vitro and in vivo studies by Ashri, Lubna Y., Abou El Ela, Amal El Sayeh F., Ibrahim, Mohamed Abbas, Alshora, Doaa Hasan, Naguib, Marianne j.

“…The objective of the present study was to optimize and evaluate a buccal mucoadhesive tenoxicam (TNX) local delivery system for the treatment of chronic…”
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Novel chewable colon targeted tablets of bumadizone calcium for treatment of ulcerative colitis: Formulation and optimization by Nour, Samia A., Abdelmalak, Nevine Shawky, Naguib, Marianne J.

“…The aim of the present study was the formulation of a novel chewable tablet containing the non-steroidal anti-inflammatory bumadizone calcium (BZ) to deliver…”
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