Search Results - "Naguib, Ibrahim A"
-
1
Facile Conversion of the Quinone-Semicarbazone Chromophore of Naftazone into a Fluorescent Quinol-Semicarbazide: Kinetic Study and Analysis of Naftazone in Pharmaceuticals and Human Serum
Published in Sensors (Basel, Switzerland) (18-08-2022)“…Naftazone is a quinone-semi carbazone drug that possesses a strong orange color, and hence it was usually analyzed colorimetrically or by HPLC-UV. However,…”
Get full text
Journal Article -
2
Development of a Novel Class of Pyridazinone Derivatives as Selective MAO-B Inhibitors
Published in Molecules (Basel, Switzerland) (13-06-2022)“…Sixteen compounds (TR1–TR16) were synthesized and evaluated for their inhibitory activities against monoamine oxidase A and B (MAOs). Most of the derivatives…”
Get full text
Journal Article -
3
Ameliorative Effect of Curcumin Nanoparticles against Monosodium Iodoacetate-Induced Knee Osteoarthritis in Rats
Published in Mediators of inflammation (14-10-2022)“…Aim. This study is aimed at evaluating the use of curcumin-loaded polylactic-co-glycolic acid nanoparticles (CUR-loaded PLGA NPs) as a treatment against…”
Get full text
Journal Article -
4
Luteolin 4'-Neohesperidoside Inhibits Clinically Isolated Resistant Bacteria In Vitro and In Vivo
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Multidrug resistance (MDR) pathogens are usually associated with higher morbidity and mortality rates. Flavonoids are good candidates for the development of…”
Get full text
Journal Article -
5
Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route
Published in Pharmaceuticals (Basel, Switzerland) (24-02-2022)“…This research aimed to design, optimize, and evaluate berberine-laden nanostructured lipid carriers overlaid with chitosan (BER-CTS-NLCs) for efficient brain…”
Get full text
Journal Article -
6
Comparative Study of Augmented Classical Least Squares Models for UV Assay of Co-Formulated Antiemetics Together with Related Impurities
Published in Molecules (Basel, Switzerland) (01-10-2023)“…The classical least squares (CLS) model and three augmented CLS models are adopted and validated for the analysis of pyridoxine HCl (PYR), cyclizine HCl (CYC),…”
Get full text
Journal Article -
7
Design of predictive model to optimize the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug
Published in Scientific reports (30-07-2022)“…These days, many efforts have been made to increase and develop the solubility and bioavailability of novel therapeutic medicines. One of the most believable…”
Get full text
Journal Article -
8
Unveiling Antimicrobial and Antioxidant Compositional Differences between Dukkah and Za’atar via SPME-GCMS and HPLC-DAD
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Interest in plant-based diets has been on the rise in recent years owing to the potential health benefits of their individual components and the notion that…”
Get full text
Journal Article -
9
Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization
Published in Molecules (Basel, Switzerland) (01-07-2022)“…Industrial-based application of supercritical CO (SCCO ) has emerged as a promising technology in numerous scientific fields due to offering brilliant…”
Get full text
Journal Article -
10
Role of ADMA/DDAH-1 and iNOS/eNOS signaling in the gastroprotective effect of tadalafil against indomethacin-induced gastric injury
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastric ulcers represent a significant clinical concern and adversely affect the quality of life…”
Get full text
Journal Article -
11
Antioxidant and Anti-Aging Phytoconstituents from Faucaria tuberculosa: In Vitro and In Silico Studies
Published in Molecules (Basel, Switzerland) (30-09-2023)“…Research targeting natural cosmeceuticals is now increasing due to the safety and/or limited side effects of natural products that are highly valued in…”
Get full text
Journal Article -
12
Application of Three Ecological Assessment Tools in Examining Chromatographic Methods for the Green Analysis of a Mixture of Dopamine, Serotonin, Glutamate and GABA: A Comparative Study
Published in Molecules (Basel, Switzerland) (07-09-2021)“…The assessment of greenness of analytical protocols is of great importance now to preserve the environment. Some studies have analyzed either only the…”
Get full text
Journal Article -
13
Development and validation of a stability indicating RP-HPLC-DAD method for the determination of bromazepam
Published in PloS one (10-03-2021)“…A reliable, selective and sensitive stability-indicating RP-HPLC assay was established for the quantitation of bromazepam (BMZ) and one of the degradant and…”
Get full text
Journal Article -
14
Orthogonal projection to latent structures and first derivative for manipulation of PLSR and SVR chemometric models' prediction: A case study
Published in PloS one (25-09-2019)“…Novel manipulations of the well-established multivariate calibration models namely; partial least square regression (PLSR) and support vector regression (SVR)…”
Get full text
Journal Article -
15
Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis
Published in Pharmaceutics (29-06-2022)“…This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate…”
Get full text
Journal Article -
16
Hexosomal Dispersion: A Nano-Based Approach to Boost the Antifungal Potential of Citrus Essential Oils against Plant Fungal Pathogens
Published in Molecules (Basel, Switzerland) (17-10-2021)“…The demand for natural fungicides to replace synthetic ones has surged since toxic residues persist in soils, causing environmental contamination and posing a…”
Get full text
Journal Article -
17
Virtual Screening of Repurposed Drugs as Potential Spike Protein Inhibitors of Different SARS-CoV-2 Variants: Molecular Docking Study
Published in Current issues in molecular biology (04-07-2022)“…Like most of the RNA viruses, SARS-CoV-2 continuously mutates. Although many mutations have an insignificant impact on the virus properties, mutations in the…”
Get full text
Journal Article -
18
Public Perceptions Regarding the Preparedness of Government to Combat the Third Wave of COVID-19 (SARS-CoV-2) Infection Across Various States of India
Published in Disaster medicine and public health preparedness (24-01-2023)“…India has already passed through 2 waves of the coronavirus disease (COVID-19) pandemic losing many lives. The reason for losing lives may be due to the…”
Get more information
Journal Article -
19
Determination of the extremolyte ectoine in plasma and a pharmacokinetic study in rats by a validated and BAGI-evaluated UPLC-MS/MS method
Published in BMC chemistry (09-10-2024)“…Ectoine (ECT) has recently gained considerable interest in the healthcare sector due to its promising therapeutic benefits in a variety of human disorders…”
Get full text
Journal Article -
20
Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid-Polymer Hybrid Nanocarriers
Published in Pharmaceuticals (Basel, Switzerland) (01-06-2023)“…The feasibility of using lipid-polymer hybrid (LPH) nanocarriers as a potential platform for the intranasal delivery of ziprasidone (ZP), a second-generation…”
Get full text
Journal Article