Search Results - "Nagtzaam, Nicole M A"

A serum B-lymphocyte activation signature is a key distinguishing feature of the immune response in sarcoidosis compared to tuberculosis by Putera, Ikhwanuliman, Schrijver, Benjamin, Kolijn, P. Martijn, van Stigt, Astrid C., ten Berge, Josianne C. E. M., IJspeert, Hanna, Nagtzaam, Nicole M. A., Swagemakers, Sigrid M. A., van Laar, Jan A. M., Agrawal, Rupesh, Rombach, Saskia M., van Hagen, P. Martin, La Distia Nora, Rina, Dik, Willem A.

“…Sarcoidosis and tuberculosis (TB) are two granulomatous diseases that often share overlapping clinical features, including uveitis. We measured 368…”
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Mild versus strong anti-inflammatory therapy during early sepsis in mice: A matter of life and death by van den Berg, Jan Willem, van der Zee, Marten, de Bruin, Ron W. F, van Holten-Neelen, Conny, Bastiaans, Jeroen, Nagtzaam, Nicole M. A, IJzermans, Jan N. M, Benner, Robbert, Dik, Willem A

“…OBJECTIVE:A recent literature-based study suggested that low-dose corticosteroid treatment has a beneficial effect on mortality in septic patients, whereas…”
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Soluble Interleukin-2 Receptor/White Blood Cell Ratio Reflects Granulomatous Disease Progression in Common Variable Immune Deficiency by van Stigt, Astrid C., Dalm, Virgil A. S. H., Nagtzaam, Nicole M. A., van Hagen, P. Martin, Dik, Willem A., IJspeert, Hanna

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Leukocyte toll-like receptor expression in pathergy positive and negative Behçet’s disease patients by van der Houwen, Tim B, Dik, Willem A, Goeijenbier, Marco, Hayat, Manizhah, Nagtzaam, Nicole M A, van Hagen, Martin, van Laar, Jan A M

“…Abstract Objectives To investigate whether the auto-inflammatory nature and the pathergic reaction in Behçet’s disease (BD) are driven by a disturbed toll-like…”
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Baricitinib treatment in a patient with a gain-of-function mutation in signal transducer and activator of transcription 1 (STAT1) by Meesilpavikkai, Kornvalee, Dik, Willem A., Schrijver, Benjamin, Nagtzaam, Nicole M.A., Posthumus-van Sluijs, Sandra J., van Hagen, P. Martin, Dalm, Virgil A.S.H.

“…Candidiasis erupted repetitively within 2 weeks after termination of a course of antifungal therapy. [...]prophylactic antifungal therapy was required…”
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Association of monocyte HLA-DR expression over time with secondary infection in critically ill children: a prospective observational study by Hagedoorn, Nienke N., Kolukirik, Pinar, Nagtzaam, Nicole M. A., Nieboer, Daan, Verbruggen, Sascha, Joosten, Koen F., Moll, Henriette, Driessen, Gertjan, Dik, Willem A., Vermont, Clementien

“…An impaired immune response could play a role in the acquisition of secondary infections in critically ill children. Human leukocyte antigen-DR expression on…”
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Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity by Berentschot, Julia C., Drexhage, Hemmo A., Aynekulu Mersha, Daniel G., Wijkhuijs, Annemarie J. M., GeurtsvanKessel, Corine H., Koopmans, Marion P. G., Voermans, Jolanda J. C., Hendriks, Rudi W., Nagtzaam, Nicole M. A., de Bie, Maaike, Heijenbrok-Kal, Majanka H., Bek, L. Martine, Ribbers, Gerard M., van den Berg-Emons, Rita J. G., Aerts, Joachim G. J. V., Dik, Willem A., Hellemons, Merel E.

“…BackgroundMany patients with SARS-CoV-2 infection develop long COVID with fatigue as one of the most disabling symptoms. We performed clinical and immune…”
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Soluble Interleukin-2 Receptor Is a Promising Serum Biomarker for Granulomatous Disease in Common Variable Immune Deficiency by van Stigt, Astrid C., Dalm, Virgil A. S. H., Nagtzaam, Nicole M. A., van Rijswijk, Damian A., Barendregt, Barbara H., van Hagen, P. Martin, IJspeert, Hanna, Dik, Willem A.

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Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention by van der Valk, Eline S., Mulder, Daniël S., Kouwenhoven, Tessa, Nagtzaam, Nicole M. A., van Rossum, Elisabeth F. C., Dik, Willem A., Leenen, Pieter J. M.

“…BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this…”
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The role of thrombin in proliferative vitreoretinopathy by Bastiaans, Jeroen, van Meurs, Jan C, Mulder, Verena C, Nagtzaam, Nicole M A, Smits-te Nijenhuis, Marja, Dufour-van den Goorbergh, Diana C M, van Hagen, P Martin, Hooijkaas, Herbert, Dik, Willem A

“…To determine the role of thrombin in the development of proliferative vitreoretinopathy (PVR). Vitreous was collected from patients undergoing a vitrectomy…”
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Thrombin induces epithelial-mesenchymal transition and collagen production by retinal pigment epithelial cells via autocrine PDGF-receptor signaling by Bastiaans, Jeroen, van Meurs, Jan C, van Holten-Neelen, Conny, Nagtzaam, Nicole M A, van Hagen, P Martin, Chambers, Rachel C, Hooijkaas, Herbert, Dik, Willem A

“…De-differentiation of RPE cells into mesenchymal cells (epithelial-mesenchymal transition; EMT) and associated collagen production contributes to development…”
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Monocyte response after colorectal surgery: A prospective cohort study by Edomskis, Pim P., Dik, Willem A., Sparreboom, Cloë L., Nagtzaam, Nicole M. A., van Oudenaren, Adrie, Lambrichts, Daniël P. V., Bayon, Yves, van Dongen, Noah N. N., Menon, Anand G., de Graaf, Eelco J. R., Coene, Peter Paul L. O., Lange, Johan F., Leenen, Pieter J. M.

“…BackgroundTumor resection is the common approach in patients with colorectal malignancy. Profound insight into inflammatory changes that accompany the normal…”
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A Novel Heterozygous Mutation in the STAT1 SH2 Domain Causes Chronic Mucocutaneous Candidiasis, Atypically Diverse Infections, Autoimmunity, and Impaired Cytokine Regulation by Meesilpavikkai, Kornvalee, Dik, Willem A, Schrijver, Benjamin, Nagtzaam, Nicole M A, van Rijswijk, Angelique, Driessen, Gertjan J, van der Spek, Peter J, van Hagen, P Martin, Dalm, Virgil A S H

“…Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency characterized by persistent or recurrent skin and mucosal surface infections with…”
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Expression of NK cell receptors on decidual T cells in human pregnancy by Tilburgs, Tamara, van der Mast, Barbara J, Nagtzaam, Nicole M.A, Roelen, Dave L, Scherjon, Sicco A, Claas, Frans H.J

“…Abstract Specific receptors enable NK cells to discriminate between cells with normal expression of MHC class I and cells that have low or absent expression of…”
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Encapsulating peritoneal sclerosis is associated with T-cell activation by Betjes, Michiel G H, Habib, Meelad S, Struijk, Dick G, Lopes Barreto, Deirisa, Korte, Mario R, Abrahams, Alferso C, Nagtzaam, Nicole M A, Clahsen-van Groningen, Marian C, Dik, Willem A, Litjens, Nicolle H R

“…Encapsulating peritoneal sclerosis (EPS) is an excessive fibrotic response of the peritoneum that may occur after long-term peritoneal dialysis (PD). The…”
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Dexamethasone transforms lipopolysaccharide-stimulated human blood myeloid dendritic cells into myeloid dendritic cells that prime interleukin-10 production in T cells by Bosma, Brenda M, Metselaar, Herold J, Nagtzaam, Nicole M.A, de Haan, Roel, Mancham, Shanta, van der Laan, Luc J.W, Kuipers, Ernst J, Kwekkeboom, Jaap

“…Myeloid dendritic cells (MDC) play an important role in antigen-specific immunity and tolerance. In transplantation setting donor-derived MDC are a promising…”
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Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy by Shariatzadeh, Mahnaz, Nagtzaam, Nicole M A, van Vark-van der Zee, Leonie, van Holten-Neelen, Conny, Verhoeven, Adrie J M, Dehairs, Jonas, Swinnen, Johannes V, Leijten, Frank, Ten Berge, Josianne C, Ciriano, Jose P Martinez, Wong, King T, Mulder, Monique, Leenen, Pieter J M, Dik, Willem A

“…Diabetic retinopathy (DR) is a complication of type 2 diabetes mellitus (T2DM). Lipoprotein(a) (Lp(a)) contributes to the progression of DR, but how is…”
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HLA-DR Expression on Monocyte Subsets in Critically Ill Children by Boeddha, Navin P, Kerklaan, Dorian, Dunbar, Albert, van Puffelen, Esther, Nagtzaam, Nicole M A, Vanhorebeek, Ilse, Van den Berghe, Greet, Hazelzet, Jan A, Joosten, Koen F, Verbruggen, Sascha C, Dik, Willem A, Driessen, Gertjan J

“…BACKGROUND:To longitudinally study blood monocyte subset distribution and human leukocyte antigen-DR (HLA-DR) expression on monocyte subsets in children with…”
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Serum CCL17 distinguishes sarcoid uveitis from TB‐uveitis and QFT‐negative uveitis by Schrijver, Benjamin, La Distia Nora, Rina, Nagtzaam, Nicole M. A., Laar, Jan A. M., Hagen, P. Martin, Dik, Willem A.

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Soluble guanylate cyclase activator BAY 54–6544 improves vasomotor function and survival in an accelerated ageing mouse model by Ataei Ataabadi, Ehsan, Golshiri, Keivan, Jüttner, Annika A., Vries, René, den Berg‐Garrelds, Ingrid, Nagtzaam, Nicole M. A., Khan, Hina N., Leijten, Frank P. J., Brandt, Renata M. C., Dik, Willem A., Pluijm, Ingrid, Danser, A. H. Jan, Sandner, Peter, Roks, Anton J. M.

“…DNA damage is a causative factor in ageing of the vasculature and other organs. One of the most important vascular ageing features is reduced nitric oxide…”
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