Search Results - "Nagore, G."

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models by Hennika, Tammy, Hu, Guo, Olaciregui, Nagore G, Barton, Kelly L, Ehteda, Anahid, Chitranjan, Arjanna, Chang, Cecilia, Gifford, Andrew J, Tsoli, Maria, Ziegler, David S, Carcaboso, Angel M, Becher, Oren J

“…Diffuse intrinsic pontine glioma (DIPG), or high-grade brainstem glioma (BSG), is one of the major causes of brain tumor-related deaths in children. Its…”
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EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas by Mohammad, Faizaan, Weissmann, Simon, Leblanc, Benjamin, Pandey, Deo P, Højfeldt, Jonas W, Comet, Itys, Zheng, Chunqin, Johansen, Jens Vilstrup, Rapin, Nicolas, Porse, Bo T, Tvardovskiy, Andrey, Jensen, Ole N, Olaciregui, Nagore G, Lavarino, Cinzia, Suñol, Mariona, de Torres, Carmen, Mora, Jaume, Carcaboso, Angel M, Helin, Kristian

“…Although mutant H3K27M histones inhibit PRC2 in diffuse intrinsic pontine gliomas, these tumors exhibit significant amounts of PRC2 activity. The repression of…”
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Crown damage and the mortality of tropical trees by Arellano, Gabriel, Medina, Nagore G., Tan, Sylvester, Mohamad, Mohizah, Davies, Stuart J.

“…What causes individual tree death in tropical forests remains a major gap in our understanding of the biology of tropical trees and leads to significant…”
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Competition‐induced transgenerational plasticity influences competitive interactions and leaf decomposition of offspring by Puy, Javier, Bello, Francesco, Dvořáková, Hana, Medina, Nagore G., Latzel, Vit, Carmona, Carlos P.

“…Summary Phenotypic plasticity, within and across generations (transgenerational plasticity), allows organisms and their progeny to adapt to the environment…”
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Exploring the impact of data curation criteria on the observed geographical distribution of mosses by Ronquillo, Cristina, Stropp, Juliana, Medina, Nagore G., Hortal, Joaquin

“…Biodiversity data records contain inaccuracies and biases. To overcome this limitation and establish robust geographic patterns, ecologists often curate…”
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Moss establishment success is determined by the interaction between propagule size and species identity by Hurtado, Fernando, Estébanez, Belén, Aragón, Pedro, Hortal, Joaquín, Molina-Bustamante, Manuel, Medina, Nagore G.

“…Colonization of new habitat patches is a key aspect of metacommunity dynamics, particularly for sessile organisms. Mosses can establish in new patches through…”
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Evaluation of tropical–temperate transitions: An example of climatic characterization in the Asian Palmate group of Araliaceae by Coca‐de‐la‐Iglesia, Marina, Medina, Nagore G., Wen, Jun, Valcárcel, Virginia

“…Premise There has been a great increase in using climatic data in phylogenetic studies over the past decades. However, compiling the high‐quality spatial data…”
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eBryoSoil: a citizen science application to monitor changes in soil ecosystems by Mira, André F., Hortal, Joaquín, Portela, Ana Paula, Albertos, Belén, Estébanez, Belén, Branquinho, Cristina, Vieira, Cristiana, Hespanhol, Helena, Draper, Isabel, Marques, Joana, Monteiro, Juliana, Leo, María, Hurtado, Pilar, Ochoa-Hueso, Raúl, Varela, Zulema, Medina, Nagore G.

“…Biological soil covers (BSCs) play a pivotal role in ecosystem functioning by enhancing soil stability, mediating nutrient cycling, and influencing soil…”
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The onset of PI3K‐related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib by Kobialka, Piotr, Sabata, Helena, Vilalta, Odena, Gouveia, Leonor, Angulo‐Urarte, Ana, Muixí, Laia, Zanoncello, Jasmina, Muñoz‐Aznar, Oscar, Olaciregui, Nagore G, Fanlo, Lucia, Esteve‐Codina, Anna, Lavarino, Cinzia, Javierre, Biola M, Celis, Veronica, Rovira, Carlota, López‐Fernández, Susana, Baselga, Eulàlia, Mora, Jaume, Castillo, Sandra D, Graupera, Mariona

“…Low‐flow vascular malformations are congenital overgrowths composed of abnormal blood vessels potentially causing pain, bleeding and obstruction of different…”
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Shifts in the importance of the species pool and environmental controls of epiphytic bryophyte richness across multiple scales by Medina, Nagore G., Bowker, Matthew A., Hortal, Joaquín, Mazimpaka, Vicente, Lara, Francisco

“…Species richness is influenced by a nested set of environmental factors, but how do these factors interact across several scales? Our main aim is to…”
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Current climate, but also long‐term climate changes and human impacts, determine the geographic distribution of European mammal diversity by Santos, Ana M. C., Cianciaruso, Marcus V., Barbosa, Ana Márcia, Bini, L. Mauricio, Diniz‐Filho, J. Alexandre F., Faleiro, Frederico V., Gouveia, Sidney F., Loyola, Rafael, Medina, Nagore G., Rangel, Thiago F., Tessarolo, Geiziane, Hortal, Joaquín

“…AIM: Historical climate variations, current climate and human impacts are known to influence current species richness, but their effects on phylogenetic and…”
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TSPO PET Imaging as a Potent Non-Invasive Biomarker for Diffuse Intrinsic Pontine Glioma in a Patient-Derived Orthotopic Rat Model by Chevaleyre, Céline, Kereselidze, Dimitri, Caillé, Fabien, Tournier, Nicolas, Olaciregui, Nagore G., Winkeler, Alexandra, Declèves, Xavier, Jego, Benoit, Cisternino, Salvatore, Auvity, Sylvain, Truillet, Charles

“…Diffuse intrinsic pontine gliomas (DIPG), the first cause of cerebral pediatric cancer death, will greatly benefit from specific and non-invasive biomarkers…”
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The interplay between climatic niche evolution, polyploidy and reproductive traits explains plant speciation in the Mediterranean Basin: a case study in Centaurium (Gentianaceae) by Valdés-Florido, Ana, Valcárcel, Virginia, Maguilla, Enrique, Díaz-Lifante, Zoila, Andrés-Camacho, Cristina, Zeltner, Louis, Coca-de-la-Iglesia, Marina, Medina, Nagore G, Arroyo, Juan, Escudero, Marcial

“…Speciation and diversification patterns in angiosperms are frequently shaped by niche evolution. Hill is a Mediterranean genus with ca. 25 species, of which…”
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Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8 by Monterrubio, Carles, Paco, Sonia, Olaciregui, Nagore G., Pascual-Pasto, Guillem, Vila-Ubach, Monica, Cuadrado-Vilanova, Maria, Ferrandiz, M. Mar, Castillo-Ecija, Helena, Glisoni, Romina, Kuplennik, Nataliya, Jungbluth, Achim, de Torres, Carmen, Lavarino, Cinzia, Cheung, N.K.V., Mora, Jaume, Sosnik, Alejandro, Carcaboso, Angel M.

“…Neuroblastoma is a pediatric solid tumor with high expression of the tumor associated antigen disialoganglioside GD2. Despite initial response to induction…”
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Climatic niche pre-adaptation facilitated island colonization followed by budding speciation in the Madeiran ivy (Hedera maderensis, Araliaceae) by Alonso, Alejandro, Gallego-Narbón, Angélica, Coca-de-la-Iglesia, Marina, Monjas, David, Medina, Nagore G., Fernández-Mazuecos, Mario, Valcárcel, Virginia

“…The path followed by species in the colonization of remote oceanic islands ultimately depends on their phylogenetic constraints and ecological responses. In…”
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Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01 by Pascual-Pasto, Guillem, Bazan-Peregrino, Miriam, Olaciregui, Nagore G, Restrepo-Perdomo, Camilo A, Mato-Berciano, Ana, Ottaviani, Daniela, Weber, Klaus, Correa, Genoveva, Paco, Sonia, Vila-Ubach, Monica, Cuadrado-Vilanova, Maria, Castillo-Ecija, Helena, Botteri, Gaia, Garcia-Gerique, Laura, Moreno-Gilabert, Helena, Gimenez-Alejandre, Marta, Alonso-Lopez, Patricia, Farrera-Sal, Marti, Torres-Manjon, Silvia, Ramos-Lozano, Dolores, Moreno, Rafael, Aerts, Isabelle, Doz, François, Cassoux, Nathalie, Chapeaublanc, Elodie, Torrebadell, Montserrat, Roldan, Monica, König, Andrés, Suñol, Mariona, Claverol, Joana, Lavarino, Cinzia, Carmen de, Torres, Fu, Ligia, Radvanyi, François, Munier, Francis L, Catalá-Mora, Jaume, Mora, Jaume, Alemany, Ramón, Cascalló, Manel, Chantada, Guillermo L, Carcaboso, Angel M

“…Retinoblastoma is a pediatric solid tumor of the retina activated upon homozygous inactivation of the tumor suppressor VCN-01 is an oncolytic adenovirus…”
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Low Bcl-2 is a robust biomarker of sensitivity to nab-paclitaxel in Ewing sarcoma by Pascual-Pasto, Guillem, Resa-Pares, Claudia, Castillo-Ecija, Helena, Aschero, Rosario, Baulenas-Farres, Merce, Vila-Ubach, Monica, Burgueño, Victor, Balaguer-Lluna, Leire, Cuadrado-Vilanova, Maria, Olaciregui, Nagore G., Martinez-Velasco, Nuria, Perez-Jaume, Sara, de Alava, Enrique, Tirado, Oscar M., Lavarino, Cinzia, Mora, Jaume, Carcaboso, Angel M.

“…[Display omitted] Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) shows potent preclinical anticancer activity in pediatric solid tumors such as Ewing…”
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Glucosylated nanomicelles target glucose-avid pediatric patient-derived sarcomas by Bukchin, Alexandra, Pascual-Pasto, Guillem, Cuadrado-Vilanova, Maria, Castillo-Ecija, Helena, Monterrubio, Carles, Olaciregui, Nagore G., Vila-Ubach, Monica, Ordeix, Laia, Mora, Jaume, Carcaboso, Angel M., Sosnik, Alejandro

“…We report for the first time on a nano-drug delivery system based on glucosylated polymeric nanomicelles to actively target the second-generation tyrosine…”
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Long-term outcomes of ultra-hypofractionated 2 fractions single day HDR brachytherapy in localized prostate cancer by Nagore, G., Moreno-Olmedo, E., Suárez-Gironzini, V., Aakki, L., LI, Ramos-Garcia, Gómez, E., Garcia, A., Beltran, L., Gomez-Iturriaga, A.

“…•2 Fractions HDR-BT single day for localized PCa is highly curative.•10-yrs biochemical and local control were 93.3%, and 95.2%, respectively.•Our schedule of…”
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Does spore ultrastructure mirror different dispersal strategies in mosses? A study of seven iberian orthotrichum species by Medina, Nagore G, Estébanez, Belén

“…Most mosses have xerochastic dispersal (i.e., they open their capsules when conditions are dry), which is thought to favor long-distance dispersal. However,…”
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