Search Results - "Nagle, John F."
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Introductory lecture: basic quantities in model biomembranes
Published in Faraday discussions (01-01-2013)“…One of the many aspects of membrane biophysics dealt with in this Faraday Discussion regards the material moduli that describe energies at a supramolecular…”
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Structure of the DMPC lipid bilayer ripple phase
Published in Soft matter (07-02-2015)“…High resolution structure is presented for the ripple (Pβ') phase of the phospholipid dimyristoylphosphatidylcholine. Low angle X-ray scattering from oriented…”
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3
Interpretation of Fluctuation Spectra in Lipid Bilayer Simulations
Published in Biophysical journal (04-05-2011)“…Atomic resolution and coarse-grained simulations of dimyristoylphosphatidylcholine lipid bilayers were analyzed for fluctuations perpendicular to the bilayer…”
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4
Mechanical properties of lipid bilayers: a note on the Poisson ratio
Published in Soft matter (2019)“…We investigate the Poisson ratio ν of fluid lipid bilayers, i.e., the question how area strains compare to the changes in membrane thickness (or, equivalently,…”
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Temperature Dependence of Structure, Bending Rigidity, and Bilayer Interactions of Dioleoylphosphatidylcholine Bilayers
Published in Biophysical journal (01-01-2008)“…X-ray diffuse scattering was measured from oriented stacks and unilamellar vesicles of dioleoylphosphatidylcholine lipid bilayers to obtain the temperature…”
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6
Bending Rigidities and Interdomain Forces in Membranes with Coexisting Lipid Domains
Published in Biophysical journal (16-06-2015)“…To precisely quantify the fundamental interactions between heterogeneous lipid membranes with coexisting liquid-ordered (Lo) and liquid-disordered (Ld)…”
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Lipid Bilayer Structure Determined by the Simultaneous Analysis of Neutron and X-Ray Scattering Data
Published in Biophysical journal (01-09-2008)“…Quantitative structures were obtained for the fully hydrated fluid phases of dioleoylphosphatidylcholine (DOPC) and dipalmitoylphosphatidylcholine (DPPC)…”
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MEDUSA: A cloud-based tool for the analysis of X-ray diffuse scattering to obtain the bending modulus from oriented membrane stacks
Published in PLoS computational biology (01-01-2024)“…An important mechanical property of cells is their membrane bending modulus, κ. Here, we introduce MEDUSA (MEmbrane DiffUse Scattering Analysis), a cloud-based…”
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The bending rigidity of the red blood cell cytoplasmic membrane
Published in PloS one (01-08-2022)“…An important mechanical property of cells is the membrane bending modulus, κ. In the case of red blood cells (RBCs) there is a composite membrane consisting of…”
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10
Structural determinants of water permeability through the lipid membrane
Published in The Journal of general physiology (01-01-2008)“…Despite intense study over many years, the mechanisms by which water and small nonelectrolytes cross lipid bilayers remain unclear. While prior studies of…”
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11
Orientation of Tie-Lines in the Phase Diagram of DOPC/DPPC/Cholesterol Model Biomembranes
Published in Langmuir (16-11-2010)“…We report the direction of tie-lines of coexisting phases in a ternary diagram of DOPC/DPPC/cholesterol lipid bilayers, which has been a system of interest in…”
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Determination of Electron Density Profiles and Area from Simulations of Undulating Membranes
Published in Biophysical journal (04-05-2011)“…The traditional method for extracting electron density and other transmembrane profiles from molecular dynamics simulations of lipid bilayers fails for large…”
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13
Structure of Fully Hydrated Fluid Phase DMPC and DLPC Lipid Bilayers Using X-Ray Scattering from Oriented Multilamellar Arrays and from Unilamellar Vesicles
Published in Biophysical journal (01-04-2005)“…Quantitative structures of the fully hydrated fluid phases of dimyristoylphosphatidylcholine (DMPC) and dilauroylphosphatidylcholine (DLPC) were obtained at 30…”
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Phase behavior of palmitoyl and egg sphingomyelin
Published in Chemistry and physics of lipids (01-07-2018)“…[Display omitted] •X-ray scattering from hydrated, oriented sphingomyelin (SM) samples clearly distinguishes phases.•Egg SM (ESM) forms a stable ripple phase…”
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15
Closer Look at Structure of Fully Hydrated Fluid Phase DPPC Bilayers
Published in Biophysical journal (01-06-2006)“…X-ray data are presented for the benchmark dipalmitoylphosphatidylcholine lipid bilayer in the most biologically relevant state in which the bilayers are fully…”
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Order Parameters and Areas in Fluid-Phase Oriented Lipid Membranes Using Wide Angle X-Ray Scattering
Published in Biophysical journal (01-07-2008)“…We used wide angle x-ray scattering (WAXS) from stacks of oriented lipid bilayers to measure chain orientational order parameters and lipid areas in model…”
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17
Alamethicin in lipid bilayers: Combined use of X-ray scattering and MD simulations
Published in Biochimica et biophysica acta (01-06-2009)“…We study fully hydrated bilayers of two di-monounsaturated phospholipids diC18:1PC (DOPC) and diC22:1PC with varying amounts of alamethicin (Alm). We combine…”
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Simulation-Based Methods for Interpreting X-Ray Data from Lipid Bilayers
Published in Biophysical journal (15-04-2006)“…The fully hydrated liquid crystalline phase of the dimyristoylphosphatidycholine lipid bilayer at 30°C was simulated using molecular dynamics with the CHARMM…”
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Structure of Gel Phase DMPC Determined by X-Ray Diffraction
Published in Biophysical journal (01-12-2002)“…The structure of fully hydrated gel phase dimyristoylphosphatidylcholine lipid bilayers was obtained at 10°C. Oriented lipid multilayers were used to obtain…”
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Lipid bilayers: thermodynamics, structure, fluctuations, and interactions
Published in Chemistry and Physics of Lipids (2004)“…This article, adapted from our acceptance speech of the Avanti Award in Lipids at the 47th Biophysical Society meeting in San Antonio, 2003, summarizes over 30…”
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