Search Results - "Nagle, Advait S"

Road towards new antimalarials - overview of the strategies and their chemical progress by Wu, Tao, Nagle, Advait S, Chatterjee, Arnab K

“…Malaria is a major health and economic threat to about 40% of the world's population. The absence of effective vaccines and widespread resistance to many of…”
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Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis by Nagle, Advait S., Khare, Shilpi, Kumar, Arun Babu, Supek, Frantisek, Buchynskyy, Andriy, Mathison, Casey J. N., Chennamaneni, Naveen Kumar, Pendem, Nagendar, Buckner, Frederick S., Gelb, Michael H., Molteni, Valentina

“…Nagle et al examine recent developments in drug discovery for Leishmaniasis and human African trypanosomiasis…”
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Cesium Effect:  High Chemoselectivity in Direct N-Alkylation of Amines by Salvatore, Ralph Nicholas, Nagle, Advait S., Jung, Kyung Woon

“…A novel method for the mono-N-alkylation of primary amines, diamines, and polyamines was developed using cesium bases in order to prepare secondary amines…”
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Efficient Carbamate Synthesis via a Three-Component Coupling of an Amine, CO2, and Alkyl Halides in the Presence of Cs2CO3 and Tetrabutylammonium Iodide by Salvatore, Ralph N, Shin, Seung Il, Nagle, Advait S, Jung, Kyung Woon

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Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness by Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek

“…A selective inhibitor of the kinetoplastid proteasome (GNF6702) is identified that is highly efficacious in vivo , clearing the parasites that cause…”
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Efficient Cs2CO3-promoted solution and solid phase synthesis of carbonates and carbamates in the presence of TBAI by Salvatore, Ralph N, Chu, Feixia, Nagle, Advait S, Kapxhiu, Elona A, Cross, Richard M, Jung, Kyung Woon

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Cesium Hydroxide Promoted Chemoselective N-Alkylation for the Generally Efficient Synthesis of Secondary Amines by Salvatore, Ralph N, Nagle, Advait S, Schmidt, Shaun E, Jung, Kyung Woon

“…Selective N-alkylation of primary amines was developed using cesium hydroxide to prepare various secondary amines efficiently. A cesium base not only promoted…”
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CsOH-promoted chemoselective mono-N-alkylation of diamines and polyamines by Salvatore, Ralph N, Schmidt, Shaun E, Shin, Seung Il, Nagle, Advait S, Worrell, Jay H, Jung, Kyung Woon

“…Selective N-alkylation of diamines and polyamines was carried out using cesium hydroxide, 4 Å molecular sieves, and DMF. This protocol was highly…”
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Efficient synthesis of β-amino bromides by Nagle, Advait S, Salvatore, Ralph N, Chong, Byong-Don, Woon Jung, Kyung

“…β-Aminoalcohols were smoothly converted to β-amino bromides using thionyl bromide and DMF, which were easily isolated without any further purification…”
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Selective mono protection of diols, diamines, and amino alcohols using cesium bases by Nagle, Advait S, Salvatore, Ralph N, Cross, Richard M, Kapxhiu, Elona A, Sahab, Suma, Yoon, Cheol Hwan, Jung, Kyung Woon

“…Efficient synthetic methods were developed for the synthesis of mono xanthates, as well as mono dithiocarbamates of diamines and amino alcohols. This protocol…”
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Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase by Miller, Laura Aaron, Baumgart, Laura E, Chew, Geoffrey H, deLong, Mitchell A, Galloway, Lamar C, Jung, Kyung Woon, Merkler, Kathleen A, Nagle, Advait S, Poore, Derek D, Yoon, Cheol Hwan, Merkler, David J

“…The C-terminal alpha-amide moiety of most peptide hormones arises by the posttranslational cleavage of a glycine-extended precursor in a reaction catalyzed by…”
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Efficient Carbamate Synthesis via a Three-Component Coupling of an Amine, CO 2 , and Alkyl Halides in the Presence of Cs 2 CO 3 and Tetrabutylammonium Iodide by Salvatore, Ralph N., Shin, Seung Il, Nagle, Advait S., Jung, Kyung Woon

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Efficient Cs 2CO 3-promoted solution and solid phase synthesis of carbonates and carbamates in the presence of TBAI by Salvatore, Ralph N, Chu, Feixia, Nagle, Advait S, Kapxhiu, Elona A, Cross, Richard M, Jung, Kyung Woon

“…Novel solution and solid-phase methods for the synthesis of carbonates and carbamates were developed using cesium bases and TBAI via a three-component…”
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Glutathione, S-substituted glutathiones, and leukotriene C 4 as substrates for peptidylglycine α-amidating monooxygenase by Miller, Laura Aaron, Baumgart, Laura E, Chew, Geoffrey H, deLong, Mitchell A, Galloway, Lamar C, Jung, Kyung Woon, Merkler, Kathleen A, Nagle, Advait S, Poore, Derek D, Yoon, Cheol Hwan, Merkler, David J

“…The C-terminal α-amide moiety of most peptide hormones arises by the posttranslational cleavage of a glycine-extended precursor in a reaction catalyzed by…”
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