Search Results - "Nagendra, H.G."

Role of water in plasticity, stability, and action of proteins: The crystal structures of lysozyme at very low levels of hydration by Nagendra, H.G., Sukumar, N., Vijayan, M.

“…Earlier studies involving water‐mediated transformations in lysozyme and ribonuclease A have shown that the overall movements in the protein molecule…”
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Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator by Poyya, Jagadeesha, Kumar, D. Jagadeesha, Nagendra, H.G., Dinesh, B., Aditya Rao, S.J., Joshi, Chandrashekhar G.

“…TP53 (tumor protein 53)-induced glycolysis and apoptosis regulator (TIGAR) belongs to the phosphatases family of proteins that modulates the level of reactive…”
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Characterization of hypothetical protein VNG0128C from Halobacterium NRC-1 reveals GALE like activity and its involvement in Leloir pathway of galactose metabolism by Reshma, S.V., Sathyanarayanan, Nitish, Nagendra, H.G.

“…VNG0128C, a hypothetical protein from Halobacterium NRC-1, was chosen for detailed insilico and experimental investigations. Computational exercises revealed…”
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Characterization of a hypothetical protein YVRE from Bacillus subtilis indicates its key role as glucono-lactonase in pentose phosphate pathway and glucose metabolism by Reshma, S V, Sathyanarayanan, Nitish, Nagendra, H G

“…Hypothetical proteins are functionally uncharacterized proteins with assigned function using sequence annotation tools. Almost half of the coding regions of…”
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Preferential Selectivity of Inhibitors with Human Tau Protein Kinase Gsk3β Elucidates Their Potential Roles for Off-Target Alzheimer’s Therapy by Kumar Dasappa, Jagadeesh, Nagendra, H. G.

“…Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid beta peptides (Aβ) and neurofibrillary tangles (NFTs)…”
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Sequence-structure homology recognition by iterative alignment refinement and comparative modeling by Williams, M.G., Shirai, H., Shi, J., Nagendra, H.G., Mueller, J., Mizuguchi, K., Miguel, R.N., S.C. Lovell, Innis, C.A., Deane, C.M., Chen, L., Campillo, N., Burke, D.F., Blundell, T.L., de Bakker, P.I.W.

“…Our approach to fold recognition for the fourth critical assessment of techniques for protein structure prediction (CASP4) experiment involved the use of the…”
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Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution by Nagendra, H.G, Harrington, Adrian E, Harmer, Nicholas J, Pellegrini, Luca, Blundell, Tom L, Burke, David F

“…The presence of a large number of fibroblast growth factors (FGFs) and multiple splice forms of their receptors (FGFRs) in higher vertebrates makes the…”
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