Search Results - "Nagele, P."
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Postoperative hypotension and troponin elevation: association or causation?
Published in British journal of anaesthesia : BJA (01-01-2018)Get more information
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Neuraxial block, death, and serious cardiovascular morbidity in the POISE trial
Published in British journal of anaesthesia : BJA (01-02-2014)Get full text
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Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease
Published in PloS one (02-04-2013)“…The presence of self-reactive IgG autoantibodies in human sera is largely thought to represent a breakdown in central tolerance and is typically regarded as a…”
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A Meta-Analysis of CYP2D6 Metabolizer Phenotype and Metoprolol Pharmacokinetics
Published in Clinical pharmacology and therapeutics (01-09-2013)“…Metoprolol, a commonly prescribed β‐blocker, is primarily metabolized by cytochrome P450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity…”
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Heart Failure After Right Ventricular Myocardial Infarction
Published in Current heart failure reports (01-12-2022)“…Purpose of Review Heart failure (HF) after right ventricular myocardial infarction (RVMI) is common and complicates its clinical course. This review aims to…”
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Impaired retinal micro-vascular function in patients with atrial fibrillation
Published in International journal of cardiology (01-03-2024)“…Cardiovascular (CV) risk factors and CV diseases, in particular heart failure, are strongly associated with impaired microvascular retinal endothelial…”
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Pulmonary artery pressure‐based telemedicine in heart failure: ready for Europe?
Published in European journal of heart failure (01-05-2017)Get full text
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Sodium-glucose co-transporter 2 inhibitors in left ventricular assist device and heart transplant recipients: a mini-review
Published in Heart failure reviews (08-11-2024)“…Abstract In recent years, sodium-glucose co-transporter 2 inhibitors (SGLT2i) emerged as promising therapeutic agents in managing heart failure (HF). They…”
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Not even a zebra: when an 'ordinary acute coronary syndrome' turns out to be a thyrotoxicosis-associated takotsubo syndrome
Published in European heart journal (01-10-2020)Get full text
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Prognostic capabilities of coronary computed tomographic angiography before non-cardiac surgery: prospective cohort study
Published in BMJ (Online) (22-04-2015)“…Objectives To determine if coronary computed tomographic angiography enhances prediction of perioperative risk in patients before non-cardiac surgery and to…”
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Analysis of causes of death in patients with implanted defibrillators
Published in Clinical research in cardiology (01-06-2021)“…Aims Implantable cardioverter defibrillators (ICDs) are used for primary or secondary prevention of sudden cardiac death. We sought to clarify prognosis and…”
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Diabetes and hypercholesterolemia increase blood-brain barrier permeability and brain amyloid deposition: beneficial effects of the LpPLA2 inhibitor darapladib
Published in Journal of Alzheimer's disease (01-01-2013)“…Diabetes mellitus (DM) and hypercholesterolemia (HC) have emerged as major risk factors for Alzheimer's disease, highlighting the importance of vascular health…”
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An unexpected cause of angina and survived sudden cardiac death
Published in European heart journal (01-10-2017)Get full text
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Misuse of standard error of the mean (sem) when reporting variability of a sample. A critical evaluation of four anaesthesia journals
Published in British journal of anaesthesia : BJA (01-04-2003)“…Background. In biomedical research papers, authors often use descriptive statistics to describe the study sample. The standard deviation (sd) describes the…”
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High-sensitivity cardiac troponin T in young, healthy adults undergoing non-cardiac surgery
Published in British journal of anaesthesia : BJA (01-02-2018)“…It is unclear if isolated postoperative cardiac-troponin elevation, often referred to as myocardial injury, represents a pathological event, as control studies…”
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Detection of Alzheimer's disease at mild cognitive impairment and disease progression using autoantibodies as blood-based biomarkers
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2016)“…Abstract Introduction There is an urgent need to identify biomarkers that can accurately detect and diagnose Alzheimer's disease (AD). Autoantibodies are…”
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Endothelial dysfunction in COVID-19: Current findings and therapeutic implications
Published in Atherosclerosis (01-12-2020)“…Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary complications such as acute myocardial injury, renal failure or thromboembolic…”
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Nitrous Oxide ( N2O) Requires the N-Methyl-D-Aspartate Receptor for Its Action in Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-2004)“…Nitrous oxide ( N2O, also known as laughing gas) and volatile anesthetics (VAs), the original and still most widely used general anesthetics, produce…”
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Pre‐operative vitamin B infusion and prevention of nitrous oxide‐induced homocysteine increase
Published in Anaesthesia (01-07-2010)“…Summary Nitrous oxide inactivates vitamin B12 with detrimental consequences for folate and methionine metabolism, detectable by an increase in total plasma…”
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