Search Results - "Nagel, Simon"

Antibody-mediated procoagulant platelets in SARS-CoV-2- vaccination associated immune thrombotic thrombocytopenia by Althaus, Karina, Möller, Peter, Uzun, Günalp, Singh, Anurag, Beck, Annika, Bettag, Martin, Bösmüller, Hans, Guthoff, Martina, Dorn, Franziska, Petzold, Gabor C, Henkes, Hans, Heyne, Nils, Jumaa, Hassan, Kreiser, Kornelia, Limpach, Caroline, Luz, Beate, Maschke, Matthias, Müller, Janis A, Münch, Jan, Nagel, Simon, Pötzsch, Bernd, Müller, Jens, Schlegel, Christoph, Viardot, Andreas, Bäzner, Hansjörg, Wolf, Marc, Pelzl, Lisann, Warm, Verena, Willinek, Winfried A, Steiner, Jochen, Schneiderhan-Marra, Nicole, Vollherbst, Dominik, Sachs, Ulrich J, Fend, Falko, Bakchoul, Tamam

“…The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. To prevent severe infection, mass COVID-19 vaccination campaigns with…”
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Predictors for Failure of Early Neurological Improvement After Successful Thrombectomy in the Anterior Circulation by Weyland, Charlotte S., Mokli, Yahia, Vey, Johannes A., Kieser, Meinhard, Herweh, Christian, Schönenberger, Silvia, Bendszus, Martin, Möhlenbruch, Markus A., Ringleb, Peter A., Nagel, Simon

“…Failure of early neurological improvement (fENI) despite successful mechanical thrombectomy in the anterior circulation is a clinically frequent occurrence…”
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Computer-aided imaging analysis in acute ischemic stroke - background and clinical applications by Mokli, Yahia, Pfaff, Johannes, Dos Santos, Daniel Pinto, Herweh, Christian, Nagel, Simon

“…Tools for medical image analysis have been developed to reduce the time needed to detect abnormalities and to provide more accurate results. Particularly,…”
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Endovascular versus Medical Management of Acute Basilar Artery Occlusion: A Systematic Review and Meta-Analysis of the Randomized Controlled Trials by Abdalkader, Mohamad, Finitsis, Stephanos, Li, Chuanhui, Hu, Wei, Liu, Xinfeng, Ji, Xunming, Huo, Xiaochuan, Alemseged, Fana, Qiu, Zhongming, Strbian, Daniel, Puetz, Volker, Siegler, James E, Yaghi, Shadi, Asif, Kaiz, Klein, Piers, Zhu, Yuyou, Campbell, Bruce C V, Chen, Hui-Sheng, Nagel, Simon, Tsivgoulis, Georgios, Miao, Zhongrong, Nogueira, Raul G, Jovin, Tudor G, Schonewille, Wouter J, Nguyen, Thanh N

“…The optimal management of patients with acute basilar artery occlusion (BAO) is uncertain. We aimed to evaluate the safety and efficacy of endovascular…”
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Editorial: Challenges in Posterior Circulation Ischemic Stroke by Puetz, Volker, Strbian, Daniel, Nguyen, Thanh N., Nagel, Simon

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Mechanical Thrombectomy in Isolated Occlusion of the Proximal Posterior Cerebral Artery by Herweh, Christian, Abdalkader, Mohamad, Nguyen, Thanh N., Puetz, Volker, Schöne, Daniela, Kaiser, Daniel, Chen, Chih-Hao, Jeng, Jiann-Shing, Möhlenbruch, Markus A., Ringleb, Peter A., Nagel, Simon

“…Introduction: Endovascular therapy (EVT) is established as first-line treatment for acute ischemic stroke (AIS) due to large vessel occlusion (LVO) in the…”
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Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review by Bose, Gauruv, Graveline, Justin, Yogendrakumar, Vignan, Shorr, Risa, Fergusson, Dean A, Le Gal, Gregoire, Coutinho, Jonathan, Mendonça, Marcelo, Viana-Baptista, Miguel, Nagel, Simon, Dowlatshahi, Dar

“…ObjectivesCurrent guidelines do not recommend direct oral anticoagulants (DOACs) to treat cerebral venous thrombosis (CVT) despite their benefits over standard…”
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Leaving the day behind: endovascular therapy beyond 24 h in acute stroke of the anterior and posterior circulation by Purrucker, Jan C., Ringleb, Peter A., Seker, Fatih, Potreck, Arne, Nagel, Simon, Schönenberger, Silvia, Berberich, Anne, Neuberger, Ulf, Möhlenbruch, Markus, Weyland, Charlotte

“…Background: There is little evidence of endovascular therapy (EVT) being performed in acute ischemic stroke beyond 24 h, and that evidence is limited to…”
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HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice by Chen, Ruoli L., Ogunshola, O. O., Yeoh, Karkheng K., Jani, Anant, Papadakis, Michalis, Nagel, Simon, Schofield, Christopher J., Buchan, Alastair M.

“…This study investigated the effects of 2‐(1‐chloro‐4‐hydroxyisoquinoline‐3‐carboxamido) acetic acid (IOX3), a selective small molecule inhibitor of…”
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Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats by Nagel, Simon, Papadakis, Michalis, Chen, Ruoli, Hoyte, Lisa C, Brooks, Keith J, Gallichan, Daniel, Sibson, Nicola R, Pugh, Chris, Buchan, Alastair M

“…Dimethyloxalylglycine (DMOG) is an inhibitor of prolyl-4-hydroxylase domain (PHD) enzymes that regulate the stability of hypoxia-inducible factor (HIF). We…”
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Comparing Poor and Favorable Outcome Prediction With Machine Learning After Mechanical Thrombectomy in Acute Ischemic Stroke by Mutke, Matthias A, Madai, Vince I, Hilbert, Adam, Zihni, Esra, Potreck, Arne, Weyland, Charlotte S, Möhlenbruch, Markus A, Heiland, Sabine, Ringleb, Peter A, Nagel, Simon, Bendszus, Martin, Frey, Dietmar

“…Outcome prediction after mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and large vessel occlusion (LVO) is commonly performed by…”
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Clinical outcome, recanalization success, and time metrics in drip-and-ship vs. drive-the-doctor: A retrospective analysis of the HEI-LU-Stroke registry by Urbanek, Christian, Jung, Jasmin, Güney, Resul, Potreck, Arne, Nagel, Simon, Grau, Armin J, Boujan, Timan, Luckscheiter, Andre, Bendszus, Martin, Möhlenbruch, Markus A, Seker, Fatih

“…This study aimed at comparing clinical outcome, recanalization success and time metrics in the "drip and ship" (DS) vs. "drive the doctor" (DD) concept in a…”
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Hyperdense Artery Sign in Patients With Acute Ischemic Stroke-Automated Detection With Artificial Intelligence-Driven Software by Weyland, Charlotte Sabine, Papanagiotou, Panagiotis, Schmitt, Niclas, Joly, Olivier, Bellot, Pau, Mokli, Yahia, Ringleb, Peter Arthur, Kastrup, A, Möhlenbruch, Markus A, Bendszus, Martin, Nagel, Simon, Herweh, Christian

“…Hyperdense artery sign (HAS) on non-contrast CT (NCCT) can indicate a large vessel occlusion (LVO) in patients with acute ischemic stroke. HAS detection…”
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Efficacy and safety of bridging thrombolysis initiated before transfer in a drip-and-ship stroke service by Purrucker, Jan Christoph, Heyse, Miriam, Nagel, Simon, Gumbinger, Christoph, Seker, Fatih, Möhlenbruch, Markus, Ringleb, Peter Arthur

“…ObjectiveData regarding the efficacy and safety of bridging thrombolysis (BT) initiated before transfer for evaluation of endovascular therapy is…”
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Age-Dependent Differences in the Rate and Symptoms of TIA Mimics in Patients Presenting With a Suspected TIA to a Neurological Emergency Room by Ippen, Franziska Maria, Walter, Fabian, Hametner, Christian, Gumbinger, Christoph, Nagel, Simon, Purrucker, Jan C, Mundiyanapurath, Sibu

“…Transient ischemic attack (TIA) needs further diagnostic evaluation to prevent future ischemic stroke. However, prophylaxis can be harmful in elderly if the…”
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Mechanical Thrombectomy in the Late Presentation of Anterior Circulation Large Vessel Occlusion Stroke: A Guideline From the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee by Nguyen, Thanh N, Castonguay, Alicia C, Siegler, James E, Nagel, Simon, Lansberg, Maarten G, de Havenon, Adam, Sheth, Sunil A, Abdalkader, Mohamad, Tsai, Jenny, Albers, Gregory W, Masoud, Hesham E, Jovin, Tudor G, Martins, Sheila O, Nogueira, Raul G, Zaidat, Osama O

“…Recent clinical trials investigating endovascular therapy (EVT) in the extended time window have opened new treatment paradigms for late-presenting patients…”
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Therapeutic manipulation of the HIF hydroxylases by Nagel, Simon, Talbot, Nick P, Mecinović, Jasmin, Smith, Thomas G, Buchan, Alastair M, Schofield, Christopher J

“…The hypoxia-inducible factor (HIF) family of transcription factors is responsible for coordinating the cellular response to low oxygen levels in animals. By…”
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Patient Pathways During Acute in-Hospital Stroke Treatment: A Qualitative Multi-Method Study by Busetto, Loraine, Hoffmann, Johanna, Stang, Christina, Amiri, Hemasse, Seker, Fatih, Purrucker, Jan, Ringleb, Peter Arthur, Nagel, Simon, Bendszus, Martin, Wick, Wolfgang, Gumbinger, Christoph

“…Patients experiencing acute ischemic stroke should access treatment as soon as possible to increase their chances for survival without severe disability. Given…”
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Poststroke Infections are an Independent Risk Factor for Poor Functional Outcome after Three-months in Thrombolysed Stroke Patients by Rocco, Andrea, Fam, Geraldine, Sykora, Marek, Diedler, Jennifer, Nagel, Simon, Ringleb, Peter

“…Background Infections are common complications in patients with acute ischemic stroke; however, the pathophysiology of the stroke-induced immunodepression is…”
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Chronic intracranial hypertension after cerebral venous and sinus thrombosis - frequency and risk factors by Geisbüsch, Christina, Herweh, Christian, Gumbinger, Christoph, Ringleb, Peter A, Möhlenbruch, Markus A, Nagel, Simon

“…Cerebral venous sinus thrombosis (CVST) can infrequently lead to chronical intracranial hypertension (IH) due to the altered venous drainage. The aim of this…”
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