Search Results - "Nagatsuka, Takehiro"

O -GlcNAcylation-induced GSK-3β activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice by Matsuno, Mahito, Yokoe, Shunichi, Nagatsuka, Takehiro, Morihara, Hirofumi, Moriwaki, Kazumasa, Asahi, Michio

“…-GlcNAc transferase (OGT) modulates many functions of proteins -GlcNAcylation that adds -linked β- -acetylglucosamine ( -GlcNAc) to the serine/threonine…”
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Localized Surface Plasmon Resonance Detection of Biological Toxins Using Cell Surface Oligosaccharides on Glyco Chips by Nagatsuka, Takehiro, Uzawa, Hirotaka, Sato, Keita, Kondo, Satoshi, Izumi, Masayuki, Yokoyama, Kenji, Ohsawa, Isaac, Seto, Yasuo, Neri, Paola, Mori, Hiroshi, Nishida, Yoshihiro, Saito, Masato, Tamiya, Eiichi

“…We have detected biological toxins using localized surface plasmon resonance (LSPR) and synthetic glycosyl ceramides (β-lactoside, globosyl trisaccharide…”
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Silicon nitride sugar chips for detection of Ricinus communis proteins and Escherichia coli O157 Shiga toxins by Tanaka, Daiki, Uzawa, Hirotaka, Nagatsuka, Takehiro, Oba, Yuki, Hiratsuka, Atsunori, Tayama, Ken-ichi, Yoshida, Toshio, Seto, Yasuo, Dohi, Hirofumi, Nishida, Yoshihiro

“…Lactosides having either an amino-triethylene glycol or an azido-triethylene glycol were designed and synthesized, and the two derivatives were immobilized…”
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Preparation of silicon nitride biochips for reflectometric interference spectroscopic (RIfS) analysis of biological toxins and E. coli O157:H7 strain by Nagatsuka, Takehiro, Uzawa, Hirotaka, Tanaka, Daiki, Oba, Yuki, Nishida, Yoshihiro, Iwasa, Tsuyoshi, Tayama, Ken-ichi, Yoshida, Toshio, Ezaki, Takayuki, Seto, Yasuo

“…[Display omitted] •Effective activation process of bare SiN chips was developed under basic conditions.•E. coli O157 can be detected directly from culture…”
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Assembly of Glycochips with Mammalian GSLs Mimetics toward the On-site Detection of Biological Toxins by Uzawa, Hirotaka, Kondo, Satoshi, Nagatsuka, Takehiro, Miyaguchi, Hajime, Seto, Yasuo, Oshita, Aguri, Dohi, Hirofumi, Nishida, Yoshihiro, Saito, Masato, Tamiya, Eiichi

“…According to our previously proposed scheme, each of three kinds of glycosphingolipid (GSL) derivatives, that is, lactosyl ceramide [Lac–Cer (1)] and…”
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Use of Lactose against the Deadly Biological Toxin Ricin by Nagatsuka, Takehiro, Uzawa, Hirotaka, Ohsawa, Isaac, Seto, Yasuo, Nishida, Yoshihiro

“…Developing a technology for detecting and decontaminating biological toxins is needed. Ricin from Ricinus communis is a highly poisonous toxin; it was formerly…”
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Glycotechnology for Decontamination of Biological Agents: A Model Study Using Ricin and Biotin-Tagged Synthetic Glycopolymers by Nagatsuka, Takehiro, Uzawa, Hirotaka, Sato, Keita, Ohsawa, Isaac, Seto, Yasuo, Nishida, Yoshihiro

“…Two types of biotin-tagged glycopolymers carrying lactose or glucose in clusters along the polyacrylamide backbone were prepared and subjected to…”
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Preparation and evaluation of lactose-modified monoliths for the adsorption and decontamination of plant toxins and lectins by Kato, Haruhito, Uzawa, Hirotaka, Nagatsuka, Takehiro, Kondo, Satoshi, Sato, Keita, Ohsawa, Isaac, Kanamori-Kataoka, Mieko, Takei, Yoshiyuki, Ota, Shigenori, Furuno, Masahiro, Dohi, Hirofumi, Nishida, Yoshihiro, Seto, Yasuo

“…A series of sugar-modified porous silica monoliths with different sugar ligands (β-lactoside, β-N-acetyllactosaminide, β-d-galactoside,…”
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Magnetic field microscope using high-sensitivity giant magneto-resistance sensor with AC field modulation by Kikitsu, Akira, Higashi, Yoshihiro, Kurosaki, Yoshinari, Shirotori, Satoshi, Nagatsuka, Takehiro, Suzuki, Kazuhiro, Terui, Yuji

“…A new high-sensitivity giant magneto-resistance (GMR) sensor system was developed and applied to a magnetic field microscope for which a magneto-impedance (MI)…”
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Novel Glycolipid Chips with a Double Layer of Au Nanoparticles for Biological Toxin Detection by Uzawa, Hirotaka, Nagatsuka, Takehiro, Seto, Yasuo, Nishida, Yoshihiro, Saito, Masato, Tamiya, Eiichi

“…Glycolipid chips having a double layer of Au nanoparticles are proposed for detection of biological toxins. The sugar-modified chips constitute an under and an…”
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Interaction of 70-kDa heat shock protein with glycosaminoglycans and acidic glycopolymers by Harada, Yoichiro, Garenáux, Estelle, Nagatsuka, Takehiro, Uzawa, Hirotaka, Nishida, Yoshihiro, Sato, Chihiro, Kitajima, Ken

“…•Heat shock protein 70, Hsp70, is characterized for interaction with acidic glycans.•Hsp70 directly interacts with acidic glycans with sulfated Gal and GlcNAc…”
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A novel sugar-probe biosensor for the deadly plant proteinous toxin, ricin by Uzawa, Hirotaka, Ohga, Koji, Shinozaki, Yukiko, Ohsawa, Isaac, Nagatsuka, Takehiro, Seto, Yasuo, Nishida, Yoshihiro

“…Because of the illegal use of highly toxic ricin from the castor-oil plant, Ricinus communis, in bioterrorism and suspected white powder cases, anti-terrorism…”
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Library assembly of mono-, di- and tri-O-sulfated beta-D-xylopyranosides; effect of O-sulfation on pyranose ring conformation by Nagatsuka, Takehiro, Uzawa, Hirotaka, Nishida, Yoshihiro

“…With molluscan sulfatase-catalyzed de-O-sulfation reactions, a series of mono-, di- and tri-O-sulfated p-nitrophenyl beta-D-xylopyranosides were assembled and…”
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Inhibition of PrPSc formation by synthetic O-sulfated glycopyranosides and their polymers by Yamaguchi, Satoko, Nishida, Yoshihiro, Sasaki, Kenji, Kambara, Mikie, Kim, Chan-Lan, Ishiguro, Naotaka, Nagatsuka, Takehiro, Uzawa, Hirotaka, Horiuchi, Motohiro

“…Sulfated glycosaminoglycans (GAGs) and sulfated glycans inhibit formation of the abnormal isoform of prion protein (PrPSc) in prion-infected cells and prolong…”
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A novel sugar-probe biosensor for the deadly plant proteinous toxin, ricin by UZAWA, Hirotaka, OHGA, Koji, SHINOZAKI, Yukiko, OHSAWA, Isaac, NAGATSUKA, Takehiro, SETO, Yasuo, NISHIDA, Yoshihiro

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Glucuronidase-assisted Transglycosylation for the Synthesis of Highly Functional Disaccharides: β-D-Glucuronyl 6-O-Sulfo-β-D-Gluco- and -β-D-Galactopyranosides by Nagatsuka, Takehiro, Uzawa, Hirotaka, Asanuma, Hiroyuki, Nishida, Yoshihiro

“…The substrate specificity of snail (Helix pomatia and Helix aspersa), limpet (Patella vulgata), and bovine glucuronidases was examined by using p-nitrophenyl…”
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A bovine glucuronidase for assembly of beta-D-glucuronyl-(1-3)-6-O-sulfo-beta-D-gluco- and galacto-pyranosyl linkages by Uzawa, Hirotaka, Nagatsuka, Takehiro, Hiramatsu, Hideo, Nishida, Yoshihiro

“…Glucuronidase-catalyzed transglycosylation was examined by using 4-nitrophenyl beta-D-glucuronide (D-GlcA-O-pNP) as the glycosyl donor; when pNP…”
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Sulfatase-catalyzed assembly of regioselectively O-sulfonated p-nitrophenyl α- d-gluco- and α- d-mannopyranosides by Uzawa, Hirotaka, Nishida, Yoshihiro, Sasaki, Kenji, Nagatsuka, Takehiro, Hiramatsu, Hideo, Kobayashi, Kazukiyo

“…Graphic A chemoenzymic methodology is extended to the library synthesis of regioselectively O-sulfonated pNP d-gluco and d-mannopyranosides. The method…”
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