Search Results - "Nagatomo, Takamasa"
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Effect of Progranulin on Proliferation and Differentiation of Neural Stem/Progenitor Cells after Oxygen/Glucose Deprivation
Published in International journal of molecular sciences (09-02-2022)“…We previously demonstrated that sivelestat, a selective neutrophil elastase inhibitor, attenuates the cleavage of progranulin (PGRN) and ischemia-induced cell…”
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Characterization of epitopes of human monoclonal antibodies against cytomegalovirus glycoprotein B for neutralization and antibody-dependent phagocytosis
Published in Vaccine (12-07-2023)“…As congenital cytomegalovirus (CMV) infections are the leading non-genetic cause of sensorineural hearing loss and significant neurological disabilities in…”
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Single CpG site methylation controls estrogen receptor gene transcription and correlates with hormone therapy resistance
Published in The Journal of steroid biochemistry and molecular biology (01-07-2017)“…•Alteration of ERα expression occurred in AI resistant and related with acquired resistance.•ERα promoter A dominantly influenced on regulation of ERα…”
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Different epigenetic mechanisms of ERα implicated in the fate of fulvestrant-resistant breast cancer
Published in The Journal of steroid biochemistry and molecular biology (01-03-2017)“…•We evaluated the mechanism of resistance to fulvestrant in MFR and TFR cell lines.•High methylation levels upstream of the ERα gene were observed in MFR…”
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Different epigenetic mechanisms of ERa implicated in the fate of fulvestrant-resistant breast cancer
Published in The Journal of steroid biochemistry and molecular biology (01-03-2017)“…Approximately 70% of breast cancers express estrogen receptor α (ERα), which plays critical roles in breast cancer development. Fulvestrant has been…”
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Variation in Use of Estrogen Receptor-α Gene Promoters in Breast Cancer Compared by Quantification of Promoter-Specific Messenger RNA
Published in Clinical breast cancer (01-08-2014)“…Micro-Abstract Estrogen receptor (ER)-α has multiple promoters upstream of the transcriptional start points in its gene. We examined the promoter usage of 43…”
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