Search Results - "Nagatomo, Takafumi"
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Effects of bearing clearance and atmospheric temperature on performance of pinion bearings of railway vehicles
Published in Journal of advanced mechanical design, systems, and manufacturing (01-01-2020)“…In Japan, most of the gear units for transmitting driving force in railway vehicles employ one-stage speed reducers. The gear unit is composed of a pinion…”
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2
Load state of tapered roller bearings used for pinion gear of gear units in electric railway vehicle
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2022)“…The purpose of this paper is to understand the load state of pinion bearings used for a gear unit in an electric railway vehicle. For this purpose, a system…”
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3
Effect of bearing types on performance of bearings for gear units of railway vehicles
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2022)“…Helical gears are commonly used in the gear units of railway vehicles in Japan, and the bearing types used for the gear units are tapered roller bearings. In…”
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4
Functions of 5-HT2A receptor and its antagonists in the cardiovascular system
Published in Pharmacology & therapeutics (Oxford) (01-10-2004)“…The serotonin (5-hydroxytryptamine, 5-HT) receptors have conventionally been divided into seven subfamilies, most of which have several subtypes. Among them,…”
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5
Nintedanib-Induced Delayed Mucosal Healing after Adjuvant Radiation in a Case of Oropharyngeal Carcinoma
Published in Case reports in oncology (30-08-2022)“…Abstract Since the launch of imatinib in 2001, tyrosine kinase inhibitors are being used in chemotherapy for a wide range of malignant tumors. Drugs that…”
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Successful Preoperative QUAD SHOT for Bulky Parotid Carcinoma: Potential Preoperative Ultra-Hypofractionated Radiotherapy for Conversion Surgery
Published in Case reports in oncology (01-01-2023)“…Abstract QUAD SHOT is an ultra-hypofractionated radiotherapy (RT) technique that prescribes 14.0–14.8 Gy over 2 days. Although this technique has already…”
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Investigation of factors affecting the performance of pinion bearing for gear unit of railway vehicle
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2019)“…If bearings for gear units of railway vehicles are damaged by seizing, parts of the bearings come off and damage the gear and the gear box, which may lead to…”
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Preventive measures of fretting wear in contact surfaces of inner ring and backing ring of railway axle journal bearings (Combined effect of grooving and segment‐structured DLC coating towards backing rings)
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2019)“…Fretting wear is surface damage caused by repeated slight relative slips between two contact surfaces. In railway applications, fretting wear may occur between…”
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9
Effects of segment-structured DLC film on the fretting wear of railway axle journal bearings
Published in Mechanical Engineering Journal (01-01-2019)“…Fretting wear is surface damage caused by repeated slight relative slips between two contact surfaces. In railway applications, fretting wear can occur between…”
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10
Mechanism of Inverse Agonist Action of Sarpogrelate at the Constitutively Active Mutant of Human 5-HT2A Receptor Revealed by Molecular Modeling
Published in Biological & pharmaceutical bulletin (2012)“…We previously reported that sarpogrelate, a selective 5-HT2A antagonist, showed a potent inverse agonist activity to constitutively active mutant (C322K) of…”
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11
Reduction of fretting wear in contact surface of inner ring and backing ring of railway axle journal bearings
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2018)“…In an axle journal bearing of railway vehicles, it is required to reduce the fretting wear caused by the very slight relative slip between the contact surface…”
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12
Galanin receptor 2 utilizes distinct signaling pathways to suppress cell proliferation and induce apoptosis in HNSCC
Published in Molecular medicine reports (01-09-2014)“…Galanin and its receptors, GALR1 and GALR2, are tumor suppressors and represent therapeutic targets in head and neck squamous cell carcinoma (HNSCC). In the…”
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13
Being aware of potentially fatal interstitial lung disease in patients with head and neck cancer treated with concurrent cetuximab and radiotherapy
Published in Cogent medicine (01-01-2017)“…Cetuximab-induced interstitial lung disease (ILD), especially for tumors in the head and neck area, has rarely been reported. The present case may serve as an…”
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14
Effect of internal clearance on rolling element load of double row tapered roller bearings
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2016)“…An external load applied to a rolling bearing is distributed among the rolling elements. This rolling element load distribution is changed according to the way…”
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15
Constitutively Active Mutant N111G of Angiotensin II Type 1 (AT1) Receptor Induces Homologous Internalization Through Mediation of AT1-Receptor Antagonist
Published in Journal of Pharmacological Sciences (2009)“…The present study investigated the internalization behavior of the constitutively active mutant (CAM) N111G of angiotensin II type 1 (AT1) receptor and…”
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Assessment of Binding Affinity to 5-Hydroxytryptamine 2A (5-HT2A) Receptor and Inverse Agonist Activity of Naftidrofuryl: Comparison With Those of Sarpogrelate
Published in Journal of Pharmacological Sciences (2009)“…Naftidrofuryl is a peripheral vasodilator that has been clinically used in the treatment of intermittent claudication and dementia. It has 5-hydroxytryptamine…”
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17
Three Cases of Organized Hematoma of the Maxillary Sinus: Clinical Features and Immunohistological Studies for Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor 2 Expressions
Published in Case reports in otolaryngology (01-01-2015)“…Objectives. Organized hematoma (OH) is a rare, nonneoplastic, hemorrhagic lesion causing mucosal swelling and bone thinning, mainly in the maxillary sinus. We…”
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18
Engineered Mutation of Some Important Amino Acids in Angiotensin II Type 1 (AT1) Receptor Increases the Binding Affinity of AT1-Receptor Antagonists
Published in Journal of Pharmacological Sciences (2010)“…The present study was designed to examine the binding affinity and functional potency of selective angiotensin II type 1 (AT1)-receptor antagonists towards…”
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Internalization of Constitutively Active N111G Mutant of AT1 Receptor Induced by Angiotensin II–Receptor Antagonists Candesartan, Losartan, and Telmisartan: Comparison With Valsartan
Published in Journal of Pharmacological Sciences (2010)“…Based on radioligand binding and signal transduction assays in our previous study, we have determined the binding pattern and functional efficacy of the…”
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20
Effect of the contact pressure on the fretting of railway axle journal bearings
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (01-01-2016)“…The fretting wear is caused by the very slight relative slip between the contacting surfaces of the inner ring side face and the backing ring of an axle…”
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