Search Results - "Nagato, Takuya"
-
1
A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide
Published in International journal of pharmaceutics (25-03-2019)“…[Display omitted] This paper compares batch and continuous technologies in terms of product quality and process performance in pharmaceutical tablet…”
Get full text
Journal Article -
2
Determining key parameters of continuous wet granulation for tablet quality and productivity: A case in ethenzamide
Published in International journal of pharmaceutics (15-04-2020)“…[Display omitted] This paper aims to determine key parameters that affect tablet quality and productivity in continuous tablet manufacturing. Experiments were…”
Get full text
Journal Article -
3
Feed factor profile prediction model for two-component mixed powder in the twin-screw feeder
Published in International journal of pharmaceutics: X (01-06-2024)“…In continuous pharmaceutical manufacturing processes, it is crucial to control the powder flow rate. The feeding process is characterized by the amount of…”
Get full text
Journal Article -
4
Real-time monitoring of the tablet-coating process by near-infrared spectroscopy - Effects of coating polymer concentrations on pharmaceutical properties of tablets
Published in Journal of drug delivery science and technology (01-08-2018)“…In order to establish a pharmaceutical manufacturing process control system based on a Quality-by-Design concept, the pharmaceutical properties of tablets…”
Get full text
Journal Article -
5
Importance of free water in controlling granule and tablet properties in a novel granulation method, green fluidized bed granulation (GFBG)
Published in International journal of pharmaceutics (30-10-2019)“…[Display omitted] In the pharmaceutical field, green fluidized bed granulation (GFBG) is a novel and eco-friendly manufacturing technology used to produce…”
Get full text
Journal Article -
6
In vivo screening of oral formulations using rats: Effects of ingested water volume on oral absorption of BCS class I and III drugs from immediate-release formulations
Published in Journal of drug delivery science and technology (01-12-2020)“…This study investigated the effects of ingested water volume on drug absorption to confirm the applicability of rats for oral formulation screening and to…”
Get full text
Journal Article -
7
Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator
Published in Pharmaceutics (03-04-2019)“…A continuous-spray granulator (CTS-SGR) is a one-step granulation technology capable of using solutions or suspensions. The present research objectives were,…”
Get full text
Journal Article -
8
Industrial Scale Experiments towards the Development of Process Evaluation Models for Continuous Pharmaceutical Tablet Manufacturing
Published in Computer Aided Chemical Engineering (2018)“…Large-scale experimental results are presented, which compared batch and continuous pharmaceutical tablet manufacturing towards the development of process…”
Get full text
Book Chapter -
9
Control of residence time of pharmaceutical powder in a continuous mixer with impeller and scraper
Published in International journal of pharmaceutics (30-08-2020)“…[Display omitted] The control of residence time in a powder mixing process was investigated toward the development of a continuous pharmaceutical manufacturing…”
Get full text
Journal Article -
10
Development of concentration prediction models for personalized tablet manufacturing using near-infrared spectroscopy
Published in Chemical engineering research & design (01-11-2023)Get full text
Journal Article -
11
Tablet Quality-Prediction Model Using Quality Material Attributes: Toward Flexible Switching Between Batch and Continuous Granulation
Published in Journal of pharmaceutical innovation (01-12-2021)“…Purpose The purpose of the study was to develop a model to predict the critical quality attribute (CQA) of tablets during continuous and batch manufacturing…”
Get full text
Journal Article -
12
Detection of component segregation in granules manufactured by high shear granulation with over-granulation conditions using near-infrared chemical imaging
Published in International journal of pharmaceutics (30-01-2013)“…The objective of this study was to evaluate the high shear granulation process using near-infrared (NIR) chemical imaging technique and to make the findings…”
Get full text
Journal Article -
13
A novel approach to monitor coating amount by short-wavelength near-infrared spectroscopy using a tracer with a long-chain hydrocarbyl group
Published in International journal of pharmaceutics (15-12-2013)“…Investigation into the use of near-infrared (NIR) as a Process Analytical Technology has been conducted for in-process monitoring of coating amounts for oral…”
Get full text
Journal Article -
14
Developing the final product attribute prediction model in a continuous direct compression process
Published in Computer Aided Chemical Engineering (2024)“…To analyze and design pharmaceutical manufacturing processes, models that can predict critical quality attributes (CQAs) of final products from process…”
Get full text
Book Chapter