Search Results - "Nagati, Jason S."

The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment by Chen, Rui, Xu, Min, Nagati, Jason S, Hogg, Richard T, Das, Alok, Gerard, Robert D, Garcia, Joseph A

“…Optimal stress signaling by Hypoxia Inducible Factor 2 (HIF-2) during low oxygen states or hypoxia requires coupled actions of a specific coactivator/lysine…”
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Olfactory receptor 78 regulates erythropoietin and cardiorespiratory responses to hypobaric hypoxia by Wang, Benjamin, Peng, Ying-Jie, Su, Xiaoyu, Zhang, Chongxu, Nagati, Jason S, Garcia, Joseph A, Prabhakar, Nanduri R

“…Olfactory receptor (Olfr) 78 is expressed in the carotid bodies (CB) and participates in CB responses to acute hypoxia. Olfr78 is also expressed in the kidney,…”
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A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling by Nagati, Jason S, Xu, Min, Garcia, Trent, Comerford, Sarah A, Hammer, Robert E, Garcia, Joseph A

“…The response to environmental stresses by eukaryotic organisms includes activation of protective biological mechanisms, orchestrated in part by transcriptional…”
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An acetate switch regulates stress erythropoiesis by Xu, Min, Nagati, Jason S, Xie, Jian, Li, Jiwen, Walters, Holly, Moon, Young-Ah, Gerard, Robert D, Huang, Chou-Long, Comerford, Sarah A, Hammer, Robert E, Horton, Jay D, Chen, Rui, Garcia, Joseph A

“…Manipulation of acetate levels in mice can affect the activity of the hypoxia-responsive transcription factor HIF-2α and facilitate recovery from anemia. The…”
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Comparison of a mycobacterial phage assay to detect viable Mycobacterium avium subspecies paratuberculosis with standard diagnostic modalities in cattle with naturally infected Johne disease by Greenstein, Robert J, Su, Liya, Grant, Irene R, Foddai, Antonio C G, Turner, Amy, Nagati, Jason S, Brown, Sheldon T, Stabel, Judith R

“…Mycobacterium avium subspecies paratuberculosis (MAP), the cause of Johne disease, is a slow growing mycobacterium. Viable MAP detection is difficult,…”
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Mammalian acetate-dependent acetyl CoA synthetase 2 contains multiple protein destabilization and masking elements by Nagati, Jason S., Kobeissy, Philippe H., Nguyen, Minh Q., Xu, Min, Garcia, Trent, Comerford, Sarah A., Hammer, Robert E., Garcia, Joseph A.

“…Besides contributing to anabolism, cellular metabolites serve as substrates or cofactors for enzymes and may also have signaling functions. Given these roles,…”
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A mammalian acetate switch regulates stress erythropoiesis by Xu, Min, Nagati, Jason S., Xie, Jian, Li, Jiwen, Walters, Holly, Moon, Young-Ah, Gerard, Robert D., Huang, Chou-Long, Comerford, Sarah A., Hammer, Robert E., Horton, Jay D., Chen, Rui, Garcia, Joseph A.

“…Endocrine erythropoietin (Epo), which is synthesized in the kidney or liver of adult mammals, controls erythrocyte production and is regulated by the…”
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